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rome Ⅲ survey of irritable bowel syndrome among ethnic Malays

World Journal of Gastroenterology 2012年第44期18卷 6475-6480页

作者： Yeong Yeh Lee Anuar Waid Huck Joo Tan Andrew Seng Boon Chua William E Whitehead Department of Medicine School of Medical SciencesUniversity Sains MalaysiaKubang Kerian 16150Malaysia Department of Gastroenterology Sunway Medical CenterPetaling Jaya 46150Malaysia 31 Lebuh Raya Raman Ipoh Ipoh Garden SouthIpoh 31400Malaysia Center for Functional Gastrointestinal and Motility Disorders University of North Carolina at Chapel HillChapel HillCA 27599-7080United States

AIM:To survey irritable bowel syndrome(IBS) using rome Ⅲ criteria among Malays from the north-eastern region of Peninsular ***:A previously validated Malay language rome Ⅲ IBS diagnostic questionnaire was used in the current study.A prospective sample of 232 Malay subjects(80% power) was initially *** a stratified random sampling strategy,a total of 221 Malay subjects(112 subjects in a "full time job" and 109 subjects in "no full time job") were *** were visitors(friends and relatives) within the hospital compound and were representative of the local *** flags and psychosocial alarm symptoms were also assessed in the current study using previously translated and validated *** with IBS were sub-typed into constipation-predominant,diarrhea-predominant,mixed type and *** and multivariable analyses were used to test for association between socioeconomic factors and presence of red flags and psychosocial alarm features among the Malays with ***:IBS was present in 10.9%(24/221),red flags in 22.2%(49/221) and psychosocial alarm features in 9.0%(20/221).Red flags were more commonly reported in subjects with IBS(83.3%) than psychosocial alarm features(20.8%,P < 0.001).Subjects with IBS were older(mean age 41.4 years vs 36.9 years,P = 0.08),but no difference in gender was noted(P = 0.4).Using univariable analysis,IBS was significantly associated with a tertiary education,high individual income above RM1000,married status,exsmoker and the presence of red flags(all P < 0.05).In multiple logistic regression analysis,only the presence of red flags was significantly associated with IBS(odds ratio:0.02,95%CI:0.004-0.1,P < 0.001).The commonest IBS sub-type was mixed type(58.3%),followed by constipation-predominant(20.8%),diarrheapredominant(16.7%) and un-subtyped(4.2%).Four of 13 Malay females(30.8%) with IBS also had menstrual *** subjects with IBS had at least one red flag(70.8%)

关键词： Irritable bowel syndrome Malays Preva-lence rome ⅲcriteria Malaysia

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