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Advances in Reproductive Sciences 2017年第4期5卷 64-74页

作者： Herve Tchoffo Ferdinand Ngoula Jean Raphael Kana Augustave Kenfack Victor Herman Ngoumtsop Narcisse Bertin Vemo Department of Animfal Science Faculty of Agronomy and Agricultural Sciences University of Dschang Dschang Cameroon

To assess the effect of ginger rhizomes essential oil on some reproductive parameters of laying birds, 80 female Japanese quails (Coturnix coturnix japonica) aged 3 weeks and weighing between 120 - 130 g were randomly assigned into 4 dietary treatment groups in a completely randomized design. From 3 till 13 weeks, birds in group 1 (control) received distilled water orally (100 μl/kg body weight), while the other three test groups during the same period, received respectively by gavage 50, 100 and 150 μl of ginger roots essential oil per kg body weight. At 11 weeks old, eight birds per group in each treatment were randomly selected and slaughtered, blood samples collected for analysis. On the other hand, the remaining females were maintained 3 with one untreated male in identical boxes per treatment, for fertility assessment, eggs characteristics and hatchability traits. Throughout the experiment, biochemical parameters, eggs characteristics, fertility and hatchability traits were analyzed. No significant change (p > 0.05) was observed during the experimental period for body and relative ovary weights. Contrary, the relative uterus weight significantly increased (p rhizomes essential oil dose. It was concluded that ginger rhizomes essential oil enhances bird reproductive performances, proteins and reproductive hormone levels and hatchability traits in treated female quails.

关键词： Eggs Characteristics Females Japanese Quail Ginger rhizomes Essential Oil Hatchability Traits

Evaluation of the Nutritional Status and Phytomedicinal Properties of Dried rhizomes of Turmeric (<i>Curcuma longa</i>)

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Journal of Biosciences and Medicines 2020年第8期8卷 163-179页

作者： Victor Henry Azubuike Enemor Uchechukwu Chibuzo Ogbodo Ogechukwu Frances Nworji Obiajulu Christian Ezeigwe Chukwuemeka Obumneme Okpala Gloria Chiamaka Iheonunekwu Department of Applied Biochemistry Nnamdi Azikiwe University Awka Nigeria

Turmeric (Curcuma longa) belongs to the family Zingiberaceae and has long been used traditionally for centuries as a spice and medicinal elixir. Hence, the present study aimed to profile the nutritional and phytomedicinal properties of the plant in order to justify its relevance in traditional phytomedicine and advocate its application in novel pharmacological products. Using standard methods (High Performance Liquid Chromatography, Gas Chromatography-Mass Spectroscopy and Atomic Absorption Spectrophotometry), the dried rhizomes were washed, pulverized and ethanol extracts subjected to proximate, phytochemical, vitamins, amino acid and mineral determinations. Data obtained were analyzed using student’s t-test in Statistical Package for the Social Sciences version 21. Determined proximate indices indicated moisture content of 9.55%, carbohydrate (57.30%), ash (24.70%), crude fiber (1.12%), proteins (2.15%) and fat (5.32%). Mineral composition analyses showed that C. longa rhizomes had higher contents of calcium, magnesium, potassium and sodium in parts per million (ppm) at 38.68 ± 0.114, 19.75 ± 0.001, 9.20 ± 0.002 and 7.06 ± 0.014 respectively. Amino acid profile revealed the presence of both essential and non-essential types with aspartate and glutamate in higher contents at 9.78 g/100 g and 9.65 g/100 g, respectively. Findings showed also the presence of vitamins A, C and D at 254.5 ± 2.19 mg/kg, 19.47 ± 0.16 mg/kg and 10.92 ± 0.92 mg/kg, respectively. Phytochemical analyses showed the presence of phenolic compounds with high retention times. This study thus revealed that C. longa possesses various nutritional and pharmacological/medicinal components in considerable quantities and can provide the body with basic nutrients for its therapeutic needs as well as secondary compounds with tremendous phytomedicinal potentials.

关键词： Curcuma longa Nutritional Phytomedicine Traditional rhizomes

Component Composition of Essential Oils <i>Curcuma longa</i>L. (Zingiberaceae) Introduced in Uzbekistan

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American Journal of Plant Sciences 2020年第8期11卷 1247-1253页

作者： Dilnoza I. Sotiboldieva Trobjon X. Mahkamov National University of Uzbekistan Tashkent Uzbekistan Institute of Botany Academy Sciences Republic of Uzbekistan Tashkent Uzbekistan

This article presents the results of studying the component composition of essential oils of leaves and rhizomes of C. longa grown in Uzbekistan. The chemical composition of essential oils of vegetative organs of the Curcuma longa (Zingiberaceae) plant introduced in Uzbekistan was studied for the first time. Essential oils of the plant were isolated by hydrodistillation, their chemical composition was studied by chromatography-mass spectrometry. In the composition of essential oils of leaves and rhizomes C. longa L., introduced in the Tashkent oasis, found 27 and 16 components, respectively, among which the leaf is dominated by α-fellandren (33.79%), α-terpinolene (24.28%), n-cymene (12.27%), eucalyptol (9.77%), and in the rhizomes-6-(1,3-dimeth

Radix Polygoni Multiflori Praeparata and Dioscorea Bulbifera Rhizome Decoctions Display Combined Effects Detected by a Three-Probe Drug Cocktail with Substrates of Rat Hepatic Cytochrome P450 Enzymes

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Pharmacology & Pharmacy 2014年第7期5卷 736-746页

作者： Li Jiang Pingping Shan Hui Yu Jiayuan Tao Chunyan Gong Guoqing Shen Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College Nanjing China

Objectives: Radix Polygoni Multiflori Praeparata (RPMP) and Dioscorea Bulbifera rhizomes (DBR) are used in Chinese herbal medicine and have been frequently reported for adverse reactions on liver. In this research, we aimed to evaluate in vivo effects of RPMP and DBR on rat cytochrome P450 enzymes (CYP1A2, CYP2E1 and CYP3A2) with their respective substrates as probes. Methods: Rats were orally administered RPMP, DBR and RPMP/DBR combination at 12, 10 and (12 + 10) g/kg, respectively, or saline as a control, once daily for 7 days. Thereafter, a cocktail containing 10 mg/kg caffeine, 20 mg/kg chlorzoxazone and 10 mg/kg dapsone was tail vein injected to rats. At defined time points, plasma drug concentrations were simultaneously evaluated by HPLC. Pharmacokinetic parameters simulated by DAS software were used to assess RPMP and/or DBR effects on cytochrome P450 enzymes activity. ANOVA and Dunnett’s test were used for data analysis. Results: Caffeine metabolism was enhanced in RPMP animals and reduced after pretreatment with DBR, but no effect was observed in RPMP/DBR combination group. Chlorzoxazone and dapsone metabolism was enhanced in both RPMP and DBR groups and consequently in combination group. The data suggested that RPMP independently induces rat CYP1A2, CYP2E1 and CYP3A2 activity, while DBR independently inhibits activity of rat CYP1A2 and induces that of CYP2E1 and CYP3A2. RPMP/DBR combination showed no significant benefit compared with the two drugs alone and even showed a neutralized effect in CYP1A2 activity. Conclusions: Caution is needed when RPMP and/or DBR are co-administered with drugs metabolized by human CYP1A2, CYP2E1 and CYP3A4.

关键词： Radix Polygoni Multiflori Praeparata Dioscorea Bulbifera rhizomes Cytochrome P450 Herb-Drug Interactions Three-Probe Drug Cocktail

Antibacterial activity of Valeriana jatamansi against extended-spectrum β-lactamase producing Gram-negative bacteria causing urinary tract infections

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Journal of Coastal Life Medicine 2016年第10期4卷 791-794页

作者： Babar Habib Muhammad Asif Habeeb Department of Pharmaceutical Sciences Superior UniversityLahorePakistan Institute of Molecular Biology and Biotechnology The University of LahoreLahorePakistan

Objective:To find out the antibacterial activity of Valeriana jatamansi(***)rhizomes against the extended-spectrumβ-lactamases(ESBLs)producing isolates of Enterobacteriaceae ***:Confirmation of ESBLs producing Escherichia coli,Enterobacter aerogenes,Klebsiella pneumoniae and Hafnia alvei isolated from urinary tract infections was performed by double disc diffusion *** susceptibility of all ESBLs producing isolates was determined by disc diffusion method following guidelines of Clinical and Laboratory Standards *** extraction of rhizomes of *** was performed with hexane,chloroform and methanol using Soxhelt *** extracts were tested against the ESBLs producing isolates using well diffusion ***:Hexane extract showed significant results as compared to chloroform and methanol extracts with the maximum zone of inhibition(21 mm)while ciprofloxacin and amikacin were used as standard ***:Findings of the study suggested that hexane extract of *** can be used in combination with other antibiotics as alternative treatment for urinary tract infections caused by ESBLs producing strains of Enterobacteriaceae.

关键词： Hexane Cefotaxime Valeriana jatamansi Chloroform rhizomes βlactamases

Contribution of vegetative reproduction of Leymus chinensis and Carex duriuscula to population persistence during restoration succession after flood disturbance in the Songnen Plains,China

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Contribution of vegetative reproduction of Leymus chinensis ...