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Chinese herbal medicine for subacute thyroiditis:a systematic review of randomized controlled trials

Journal of Traditional Chinese Medicine 2014年第3期34卷 243-253页

作者： Hui Luo Meng Lü Xiaohua Pei Zhongyuan Xia Institute for Tibetan Medicine ChinaTibetology ResearchCenter Sino-Japanese Friendship Clinical School of Medicine Beijing University of Chinese Medicine Department of Surgery Third Affiliated Hospital Beijing University of Chinese Medicine Department of Surgery of Traditional Chinese Medicine China-Japan Friendship Hospital

OBJECTIVE:To evaluate the effectiveness and safety of Chinese herbal medicine(CHM) in the ***: Randomized controlled trials found in PubMed, Cochrane Library, and three Chinese databases were selected. RevMan 5.2 software was used to analyze the data with relative risk or mean difference, expressed with 95% of confidence interval. The quality of trials was assessed and gradedthe quality of evidence with GRADE profiler ***: Twenty one studies were included. CHM was superior to Western Medicine(include prednisone and NSAIDs) in abating fever, relieving thyroid pain, recovering blood sedimentation, improving thyroid function, and preventing hypothyroidism(P0.05) were found in recovering blood sedimentation and improving thyroid function. The incidence of adverse reactions in treatment group was lower than that in control group(relative risk was 0.12 and 95% confidence interval was 0.03-0.51). The methodological quality of trials is generally poor with a high risk of ***: CHM(particularly CHM combined withWestern Medicine) used to treat subacute thyroiditis may improve clinical symptoms and signs,reduce relapse rate, and alleviate the side effects of hormones. Due to poor methodological quality of included trials, further more high-quality studies are warranted to confirm the effectiveness and safety of CHM.

关键词： Drugs, Chinese herbal Thyroiditis, sub-acute Randomized controlled trial review, system-atic

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