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Surgical management of 143 patients with adult primary retroperitoneal tumor

World Journal of Gastroenterology 2007年第18期13卷 2619-2621页

作者： Yuan-Hong Xu Ke-Jian Guo R.en-Xuan Guo Chun-Lin Ge Yu-Lin Tian San-Guang He Department of General Surgery The First Affiliated Hospital of China Medical UniversityShenyang 110001 Liaoning Province China

AIM： To analyze the surgical management of adult primary retroperitoneal tumors （APRT） and the factors influencing the outcome after operation. METHODS： Data of 143 cases of APRT from 1990 to 2003 in the First Affiliated Hospital of China Hedical University were evaluated retrospectively. RESULTS： A total of 143 cases of APRT were treated surgically. Among them, 122 （85.3%） underwent complete resection, 16 （11.2%） incomplete resection, and 3 （3%） surgical biopsies. Twenty-nine （20.2%） underwent tumor resection plus multiple organ resections. Ninety-five malignant cases were followed up for 1 mo to 5 years. The 1-year, 3-year, and 5-year survival rates of the patients subject to complete resection was 94.9%, 76.6% and 34.3% and that of patients with incomplete resection was 80.4%, 6.7%, and 0%, respectively （P 〈 0.001）. The Cox multi-various regression analysis showed the completeness of tumor, sex and histological type were associated closely with local recurrence. CONCLUSION： Sufficient preoperative preparation and complete tumor resection play important roles in redudng recurrence and improving survival.

关键词： retroperitoneal neoplasms Surgical procedure OperaUve Recurrence

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Intra and extra pelvic multidisciplinary surgical approach of retroperitoneal sarcoma:Case series report

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World Journal of Clinical Cases 2022年第27期10卷 9693-9702页

作者： Heekyoung Song Jung Hwan Ahn Yuyeon Jung Jae Yeon Woo Jimin Cha Yang-Guk Chung Keun Ho Lee Department of Obstetrics and Gynecology Incheon St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Obstetrics and Gynecology Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Orthopaedic Surgery Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea

BACKGROUND retroperitoneal sarcoma(RPS) is a rare malignancy arising from mesenchymal cells that most commonly presents as an abdominal mass and is associated with poor *** several studies have assessed the survival benefits of wide excision,few have reported detailed methods for achieving wide excision in patients with *** To describe our experience with multidisciplinary surgical resection of RPS using intra-and extra-pelvic *** Multidisciplinary surgery is an anatomical approach that combines intra-and extra-peritoneal access within the same surgery to achieve complete RPS *** retrospective review of the records of patients who underwent multidisciplinary surgery for RPS analyzed surgical and survival *** Eight patients underwent 10 intra-and extra-pelvic surgical resections,and their median mass size was 12.75 cm(range,6-45.5 cm).Using an intrapelvic approach,laparoscopy-assisted surgery was performed in four cases and laparotomy surgery in *** an extrapelvic approach,ilioinguinal and posterior approaches were used in four cases each,and the prone position and midline skin incision were shared in *** patients’ RPS masses were removed completely,and four achieved R0 resection through intra-and extra-pelvic *** median estimated blood loss was 2000 m L(range,300-20000 m L) and the median hospitalization was 12.6 d(range,9-69 d).Reoperation was needed in two patients(one for wound necrosis and the other for bowel perforation and wound necrosis).The median overall survival rate and median progression-free survival were 64.6 and 13.7 mo,*** RPS is therapeutically challenging because of its location and high risk of ***,intra-and extra-pelvic surgical approaches can improve the macroscopic security of the surgical margin.

关键词： Margins of excision retroperitoneal neoplasms Sarcoma

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Prognostic Factors Predicting the Postoperative Survival Period Following Treatment for Primary retroperitoneal Liposarcoma

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Chinese Medical Journal 2015年第1期128卷 85-90页

作者： Xudong Zhao Peiyu Li Xiaohui Huang Lin Chen Na Liu Yaoguang She Department of General Surgery General Hospital of Chinese People's Liberation Army Beijing 100853 China

Background：Liposarcomas,which represent 20% of all adult sarcomas,are the most common histological type of malignant soft tissue *** aim of this study was to define the prognostic factors that predict the postoperative survival period for patients with primary retroperitoneal liposarcoma.Methods：The clinical data and prognoses of 71 patients with primary retroperitoneal liposarcoma who were treated in the General Hospital of the People＇s Liberation Army of China between January 1,2000 and December 31,2007 were retrospectively reviewed and analyzed.Results：The primary tumor from each patient was resected; 54.9% （39/71） were deemed R0 resections,31.0% （22/71） were R1 resections and 14.1% （10/7 l） were deemed R2 resections （palliative operations）.The median follow up was 68 months （range：1-160 months）.Of the patients who received an R1 or R2 resection of their primary tumor,96.7% （59/61） had tumor *** 1-year,3-year,and 5-year recurrence-free rates were 77.0%,29.8% and 19.7%,*** of April 2013,53 of the 71 patients had died from tumor *** overall l-year,3-year,5-year,and 10-year survival rates were 88.7%,76.1%,61.7%,and 30.4%,*** factors that were significantly associated with prognosis in the univariate analysis were age （as a categorical variable）（P =0.006）,modus operandi （P =0.000）,histologic subtype （P =0.000）,tumor grade （P =0.000）,ascites （P =0.000）,postoperative metastasis （P =0.000） and adjuvant therapy （P =0.030）.However,in the multivariate analysis,the modus operandi （P =0.000）,tumor grade （P =0.006）,ascites （P =0.027）,postoperative metastasis （P =0.023） and age （as a categorical variable）（P =0.002） were the only significant predictors of survival.Conclusions：Complete resection remains the most effective method for treating *** grade,old age （≥60 years old）,postoperative metastasis,and ascites predict poor prognoses.

关键词： General Surgery Liposarcoma retroperitoneal neoplasms Survival Therapeutics

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Metachronous multicentric giant cell tumor of bone with retroperitoneal metastasis

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Chinese Medical Journal 2014年第14期127卷 2713-2715页

作者： Deng Zhiping Ding Yi Yang Fajun Niu Xiaohui Department of Orthopaedic Oncology Beijing Jishuitan Hospital Peking University Beijing 100035 China

Giant cell tuenor （GCT）of bone is a benign but locally aggressive tumor that usually involves the epiphysis of long bones.1Rarely,these tumors metastasize to the lung, and these metastases generally have the same benign histological appearance as the primary tumor. Multicentric giant cell tumor （M-GCT） is rarer. We herein report a case of M-GCT involving the left distal radius, with retroperitoneal metastasis, and subsequent lesions in the left proximal and distal femur. The patient and family members were informed that data concerning the case would be submitted for publication, and they consented.

关键词： giant cell tumors retroperitoneal neoplasms neoplasm metastasis

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Clinical Experience of Primary retroperitoneal Tumor: Report of 600 Cases

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The Chinese-German Journal of Clinical Oncology 2005年第4期4卷 206-208页

作者：陈凛李涛李荣石怀银北京解放军总医院普外科 100853

Objective： To summarize the experience of management for primary retroperitoneal tumor （PRPT） and to analyze the factors influencing the outcome after operation. Methods： The data of 600 cases of PRPT in General Hospital of PLA were reviewed retrospectively. Results： Of 600 cases of PRPT, 546 were surgically treated. Among theme 369 were malignant and 177 benign. 366 cases were followed up for 1 month to 15 years. The 1-years 3-year, and 5-year survival rate in the patients subject to complete resection was 90.5%, 73.2% and 53.6%, respectively, and that in incomplete resection patients was 70.6%, 32.0%, 5.7% respectively （P〈0.01）. The Cox multi-various regression analysis revealed showed completeness of tumor resection, sex and histologic type were associated closely with local recurrence. Conclusion： Sufficient preoperative preparation and complete tumor resection play important roles for reducing recurrence and improving survival.

关键词： retroperitoneal neoplasms surgical procedures, operative recurrence

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