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Prevalence of SARS-CoV-2 among central retinal artery occlusion patients:A case series-HORA study report No.3

Journal of Acute Disease 2021年第4期10卷 147-149页

作者： Sunny,Chi Lik Au Callie,Ka Li Ko Department of Ophthalmology Pamela Youde Nethersole Eastern HospitalHong KongChina Department of Ophthalmology Tung Wah Eastern HospitalHong KongChina

Introduction:COVID-19 patients are susceptible to hypercoagulability,thromboembolic,and vasculitis state;central retinal artery occlusion(CRAO)could be caused by hyperviscosity syndrome,thromboembolic accidents,and *** case reports are correlating CRAO with COVID-19 *** case series aims to reveal the prevalence of SARS-CoV-2 among CRAO patients under the COVID-19 ***:Medical records of all CRAO patients who attended our tertiary referral hospital,during COVID-19 local outbreak(March to November 2020),were *** tract samples were tested for SARS-CoV-2 by the validated Xpert Xpress SARS-CoV-2 *** patients were able to cooperate,oropharyngeal saliva samples were ***,nasopharyngeal and deep throat swabs were taken by registered ***:A total of 15 CRAO patients(7 males,8 females)were identified during the 9-month study *** mean age was 72.1-years(range 45-88 year).None of the patients were infected by SARS-CoV-2 before their CRAO disease *** patients had a history of CRAO over the contralateral *** patient was diagnosed with COVID-19 up to their last follow-up(mean 255.4 days,range 152-341 days).Without any COVID-19 positive case,correlation statistical tests on SARS-CoV-2 infection and CRAO were not ***:Some of the presumed COVID-19 related CRAO cases may be just coincident with at-risk patients,as COVID-19 is prevalent across the *** in-depth research,with adjustment to known confounding risk factors,is needed to establish a genuine correlation.

关键词： COVID-19 Coronavirus SARS-CoV-2 retinal artery occlusion Central retinal artery occlusion Hyperbaric oxygen therapy

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Fundus artery occlusion caused by cosmetic facial injections

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Chinese Medical Journal 2014年第8期127卷 1434-1437页

作者： Chen Yanyun Wang Wenying Li Jipeng Yu Yajie Li Lin Lu Ning Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing Ophthalmology & Visual Science Key Laboratory Beijing 100730 China

Background With the increasing popularity of cosmetic facial filler injections in recent years, more and more associated complications have been reported. However, the causative surgical procedures and preventative measures have not been studied well up to now. The aim of this stady was to investigate the clinical characteristics and visual prognosis of fundus artery occlusion resulting from cosmetic facial filler injections. Methods Thirteen consecutive patients with fundus artery occlusion caused by facial filler injections were included. Main outcome measures were filler materials, injection sites, best-corrected visual acuity （BCVA）, fundus fluorescein angiography, and associated ocular and systemic manifestations. Results Eleven patients had ophthalmic artery occlusion （OAO） and one patient each had central retinal artery occlusion （CRAO） and anterior ischemic optic neuropathy （AION）. Injected materials included autologous fat （seven cases）, hyaluronic acid （five cases）, and bone collagen （one case）. Injection sites were the frontal area （five cases）, periocular area （two cases）, temple area （two cases）, and nose area and nasal area （4 cases）. Injected autologous fat was associated with worse final BCVA than hyaluronic acid. The BCVA of seven patients with autologous fat injection in frontal area and temple area was no light perception. Most of the patients with OAO had ocular pain, headache, ptosis, ophthalmoplegia, and no improvement in final BCVA. Conclusions Cosmetic facial injections can cause fundus artery occlusion. Autologous fat injection tends to be associated with painful blindness, ptosis, ophthalmoplegia, and poor visual outcomes. The prognosis is much worse with autologous fat injection than hyaluronic acid iniection.

关键词： autologous fat hyaluronic acid ophthalmic artery retinal artery occlusion blindness

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