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Comparison of resistive index and shear-wave elastography in the evaluation of chronic kidney allograft dysfunction

World Journal of Transplantation 2024年第1期14卷 154-163页

作者： Ameet Kumar Jesrani Syed M Faiq Rahma Rashid Tariq Ali Kalwar Rehan Mohsin Tahir Aziz Nida Amin Khan Muhammed Mubarak Department of Radiology Sindh Institute of Urology and TransplantationKarachi 74200SindhPakistan Department of Pathology Sindh Institute of Urology and TransplantationKarachi 74200SindhPakistan Department of Transplantation Sindh Institute of Urology and TransplantationKarachi 74200SindhPakistan Department of Urology Sindh Institute of Urology and TransplantationKarachi 74200SindhPakistan

BACKGROUND Detection of early chronic changes in the kidney allograft is important for timely intervention and long-term *** and novel ultrasound-based investigations are being increasingly used for this purpose with variable *** To compare the diagnostic performance of resistive index(RI)and shear wave elastography(SWE)in the diagnosis of chronic fibrosing changes of kidney allograft with histopathological *** This is a cross-sectional and comparative study.A total of 154 kidney transplant recipients were included in this study,which was conducted at the Departments of Transplantation and Radiology,Sindh Institute of Urology and Transplantation,Karachi,Pakistan,from August 2022 to February *** consecutive patients with increased serum creatinine levels and reduced glomerular filtration rate(GFR)after three months of transplantation were enrolled in this *** and RI were performed and the findings of these were evaluated against the kidney allograft biopsy results to determine their diagnostic *** The mean age of all patients was 35.32±11.08 *** these,126(81.8%)were males and 28(18.2%)were *** mean serum creatinine in all patients was 2.86±1.68 mg/dL and the mean estimated GFR was 35.38±17.27 mL/min/1.73 *** allograft biopsy results showed chronic changes in 55(37.66%)*** sensitivity,specificity,positive predictive value(PPV),and negative predictive value(NPV)of SWE for the detection of chronic allograft damage were 93.10%,96.87%%,94.73%,and 95.87%,respectively,and the diagnostic accuracy was 95.45%.For RI,the sensitivity,specificity,PPV,and NPV were 76.92%,83.33%,70.17%,and 87.62%,respectively,and the diagnostic accuracy was 81.16%.CONCLUSION The results from this study show that SWE is more sensitive and specific as compared to RI in the evaluation of chronic allograft *** can be of great help during the routine follow-up of kidney transplant recipients for screening a

关键词： Shear wave Sonoelastography resistive index Chronic allograft changes Biopsy Histopathology

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Central retinal artery resistive index and optical coherence tomography in assessment of glaucoma progression

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International Journal of Ophthalmology(English edition) 2015年第2期8卷 305-309页

作者： Ahmed F.Abdel Ghany Samer M.Botros Tamer M.El-Raggal Department of Radiodiagnosis Faculty of Medicine Ain Shams University Department of Ophthalmology Faculty of Medicine Ain Shams University

AIM: To assess the relation between central retinal artery(CRA) resistive index(RI) and retinal nerve fiber thickness measured by optical coherence tomography(OCT) in assessment of disease progress in cases of open angle ***: Twenty-three patients with diagnosed open angle glaucoma were included in this study. They were examined by colored duplex ultrasonography of CRA with estimation of RI of CRA and ophthalmic artery(OA)with estimation of CRA/OA RI ratio as well as OCT measurement of the average retinal nerve fiber layer(RNFL) thickness in order to assess the disease ***: There was strong inverse relation between the increased RI in CRA as well as the increased CRA/OA RI ratio and the decrease in average RNFL thickness in cases of open angle ***: Assessment of CRA RI can indirectly assess the vascular changes associated with glaucoma and can assess the degree of retinal atrophy helping in evaluating prognosis thus guiding the choice of treatment.

关键词： glaucoma optical coherence tomography central retinal artery duplex ophthalmic artery resistive index

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Comparison of Ultrasound Blood Flow Characteristics of the Lower Limb in Diabetics with Early-Stage Peripheral Artery Disease and Non-Diabetic Controls

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Journal of Diabetes Mellitus 2023年第2期13卷 178-195页

作者： Josephine Sekai Tityiwe Newton-Hughes Anne Azangwe Godfrey Comfort Paul Radiography Department National University of Science and Technology Bulawayo Zimbabwe School of Health and Society University of Salford Greater Manchester UK

The aim of this study was to compare lower limb blood flow in asymptomatic diabetic patients with early-stage peripheral artery disease (PAD) and non-diabetic controls using duplex ultrasound parameters. This was a comparative cohort study of lower limb blood flow in 35 Black-African diabetic patients (25 females and 10 males with early-stage PAD median age 54 [IQR, 47 - 61] years;median HbA1c 6.3 [IQR, 5.7 - 8.0]%;BMI 29.2 ± 6.7;ABI 1.1 ± 0.1) and 36 non-diabetic controls (28 females and 8 males;median age 54 [IQR, 47 - 61] years;median HbA1c 6.3 [IQR, 5.7 - 8.0] %, BMI 29.2 ± 6.7;ABI 1.1 ± 0.1). Peak systolic velocity (PSV), pulsatility index (PI) and resistive index (RI), were utilised to compare blood flow in the popliteal arteries (PA), anterior tibial arteries (ATA) and posterior tibial arteries (PTA) in addition to ankle brachial index. All the ultrasound parameters showed good (ICC ≥ 0.7;0.50 - 0.85, 95% CI) to excellent (ICC = 1.0;1.0 - 1.0, 95% CI) reliability within groups as well as acceptable variability () other than pulsatility index of the anterior tibial artery within diabetic patients (11.1% CV). PSV, RI and PI were significantly and meaningfully higher (P;d ≥ 0.33), in diabetic patients compared to non-diabetic controls except for PI - PTA (P = 0.72;d = 0.11). Differences in PSV and RI highlighted the effects of early-stage PAD on lower limb blood flow of diabetic patients. In contrast, the effects of early-stage PAD on blood flow were not demonstrated in the PTA and ATA of diabetic patients by PI.

关键词： Atherosclerosis Peak Systolic Velocity Pulsatility index resistive index

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