检索结果-南通市图书馆

在主要疟疾向量的 pyrethroid 抵抗的指示，从伊朗的疟蚊属 stephensi

Asian Pacific Journal of Tropical Medicine 2012年第9期5卷 722-726页

作者： Hassan Vatandoost Ahmad Ali Hanafi-Bojd Department of Medical Entomology and Vector Control School of Public Health & National Institue of Health ResearchTehran University of Medical SciencesP.O.Box:6446-14155TehranIran

Objective:To investiagte insecticide resistance in target species for better insecticide resistance managemnet in malaria control ***:The status of insecticide resistance to different imagicides in Anopheles stephensi(***) including DDT 4%,lambdacyhalothrin 0.50%.deltamethrin 0.05%,permethrin 0.75%,cyfluthrin 0.15%and etofenprox 0.50%was performed according to WHO standard ***:The mortality rate to lambdacyhalothrin, pennethrin,***,etofenprox and DDT was(88.0±3.2),(92.0±2.7),(52.0±5.0),(96.0±2.2),(90.0±3.0) and(41.0±5.7) percent,respectively at diagnostic dose for one hour exposure time followed by 24 h recovery ***:These results showed first indication of pyrethroid resistance in *** in a malarious area,from southern *** is widespread,multiple resistances in the country in *** to organochlorine and some report of tolerance to organophosphate insecticides and recently to ***,results of this paper will provide a clue for monitoring and mapping of insecticide resistance in the main malaria vector for implementation of any vector control.

关键词： Anophels stephensi Malaria Pesticides resisatnce

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Discrimination between upper versus lower airway components to the rise of total airway resistance measured by Pennock’s method after nasal irritant challenge

引用

Open Journal of Molecular and Integrative Physiology 2013年第3期3卷 104-110页

作者： Zuzana Biringerova Silvia Gavliakova Eva Hanuskova Tomas Buday Jana Plevkova Clinic of Anaesthesiology and Emergency Medicine Jessenius Faculty of Medicine Comenius University Martin Slovakia Department of Pathophysiology Jessenius Faculty of Medicine Comenius University Martin Slovakia

Terminals of the trigeminal afferents innervating nasal mucosa are called gate keepers, since these fibres detect substances entering the airways. Trigeminal excitation by irritants initiates airway defensive mechanisms, and it is also attributed to the influence of lower airways resistance in a term of nasobronchial reflex. This phenomenon is frequently under debate, because some investigators were unable to confirm its existence. The aim of our study was to determine, whether pharmacological approach could be useful to reach high accuracy and better interpretation of the data obtained by Pennock’s method. Pennock’s method, which is frequently used to measure airway resistance in vivo (Raw) in fact measures total airway resistance, however, the data are usually interpreted in a terms of bronchomotor response. The upper airway component, which represents approximately 40% of Raw, is commonly not considered as being important in this method. 30 Dunkin Hartley guinea pigs were exposed to nasal stimuli (TRPA1 agonist—irritant allylisothiocyanate (10 mM, AITC), TRPM8 agonist with cooling potential menthol (10-3 M) and saline as a control). Raw was measured pre challenge as baseline, after nasal provocation and further, after nasal inhalation of histamine and methacholine (10-6 M) each. The data showed rise of Raw only after nasal AITC challenge, with further increased responsiveness to histamine and methacholine (5.3 vs 10.18 vs 11.26 vs 17.32 cmH2O.s-1, p 0.05). No significant changes were detected after saline, or menthol respectively. Data obtained in further experiment and its analysis showed that pre-treatment with nasal administration of 1% oxymetazoline but without salbutamol inhalation prevented the rise of Raw after nasal irritant challenges. Raw after nasal irritant challenges rises rather due to nasal response than due to narrowing of the lower airways.

关键词： Airways resisatnce In Vivo Pennock’s Method

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：