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Indocyanine green plasma clearance rate and 99mTc-galactosyl human serum albumin single-photon emission computed tomography evaluated preoperative remnant liver

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World Journal of Clinical Cases 2022年第25期10卷 8844-8853页

作者： Kentaro Iwaki Satoshi Kaihara Ryosuke Kita Koji Kitamura Hiroki Hashida Kenji Uryuhara Department of Surgery Kobe City Medical Center General HospitalKobe 650-0046HyogoJapan

BACKGROUND Preoperative evaluation of future remnant liver reserves is important for safe *** the remnant is small,preoperative portal vein embolization(PVE)is *** volume analysis has been the primary method of preoperative evaluation,although functional examination may be more *** have used the functional evaluation liver using the indocyanine green plasma clearance rate(KICG)and 99mTc-galactosyl human serum albumin single-photon emission computed tomography(99mTc-GSA SPECT)for safe *** To analyze the safety of our institution’s system for evaluating the remnant liver *** We retrospectively reviewed the records of 23 patients who underwent preoperative *** types of remnant liver KICG were defined as follows:Anatomical volume remnant KICG(a-rem-KICG),determined as the remnant liver anatomical volume rate×KICG;and functional volume remnant KICG(frem-KICG),determined as the remnant liver functional volume rate based on 99mTc-GSA SPECT×*** either of the remnant liver KICGs were>0.05,a hepatectomy was *** factors were *** defined the marginal group as patients with a-rem-KICG of0.05 and compared the postoperative outcomes between the marginal and not marginal(both a-rem-KICG and f-rem-KICG>0.05)*** All 23 patients underwent planned *** hepatectomy,right trisectionectomy and left trisectionectomy were in 16,6 and 1 cases,*** mean of blood loss and operative time were 576 mL and 474 min,*** increased amount of frem-KICG was significantly larger than that of a-rem-KICG after PVE(0.034 vs 0.012,P=0.0273).The not marginal and marginal groups had 17(73.9%)and 6(26.1%)patients,*** complications of Clavian-Dindo classification grade II or higher and post-hepatectomy liver failure were observed in six(26.1%)and one(grade A,4.3%)patient,*** 90-d mortality was *** marginal group had no

关键词： 99mTc-galactosyl human serum albumin single-photon emission computed tomography Hepatectomy Indocyanine green Indocyanine green plasma clearance rate liver function evaluation remnant liver reserve

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