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Acta Geochimica 2006年第S1期 101-102页

作者： Hiroki Hagiwara Kouichi Terasaki Fumio Kanai Takahisa Yoshimura Junji Akai Takeo Ta kano Tadashi Hasegawa Yoh'ichi Sakai Dept. of Geological Science Niigata University Niigata Japan

The study on the release mechanism of sinomenine hydrochloride enteric osmotic pump capsule

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The study on the release mechanism of sinomenine hydrochlori...

Studies on the PEO-PPO-PEO Block Copolymer release from Alginate Hydrogel

2018年第十二届中国药物制剂大会

作者：陈轶凡 Rongfeng Hu Song Gao Anhui University of Chinese Medicine Key Laboratory of Xin'an Medicine Jointly Developed by Ministry of Education Anhui “115” Xin'an Pharmaceutical R&D Innovation Team Key Laboratory of Anhui Provincial Traditional Chinese Medicine Research and Development

Objective: The aim of this study was to establish a method for measuring the release rate of sinomenine hydrochloride enteric osmotic pump capsule and to investigate its drug release mechanism. Methods: The drug release behavior of enteric osmotic pump capsules were evaluated by similar factor method, and the effect of diffusion mechanism on drug release were studied by investigating the drug release of perforated and non-perforated capsules. The dyeing method was used to observe whether the capsule release was regulated by osmotic mechanism. And the release rate was conducted to investigate whether drug release was affected by osmotic mechanism and swelling mechanism. Results: The release of enteric osmotic pump capsule accords with the zero order release equation. The results of the release rate showed that the method had high sensitivity and good stability. The drug release in elementary enteric osmotic pump capsule was mainly affected by the osmotic pressure difference between two sides of the capsule. However, the drug release in the push-pull enteric osmotic pump capsule was inversely proportional to the osmotic difference across capsule and the content of PEO in the booster layer. Conclusion: The established method met the requirements of the determination of sinomenine hydrochloride in vitro. The release of the elementary enteric osmotic pump capsule was mainly regulated by the osmotic mechanism, while the release of the push-pull enteric osmotic pump capsule was controlled by the mechanism of osmotic and swelling.

关键词： sinomenine hydrochloride enteric osmotic pump capsule release mechanism

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Chemical Research in Chinese Universities 2001年第3期17卷 341-346页

作者： SU Yan-lei GUO Chen LIU Hui-zhou Young Scientist Laboratory of Separation Science and Engineering State Key Laboratory of Biochemical EngineeringInstitute of Chemical MatellurgyChinese Academy of SciencesBeijing 100080P.R.China

Alginate hydrogel is one of the most widely used carriers for the immobilization of microbial cells. If surfactants are encapsulated with alginate hydrogel, increasing temperature or concentration can make the encapsu... 详细信息

关键词： Sodium alginate hydrogel PEO-PPO-PEO block copolymer release mechanism

An experimental system for release simulation of internal stores in a supersonic wind tunnel

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Chinese Journal of Aeronautics 2017年第1期30卷 186-195页

作者： Liu Wei Ma Xin Jia Zhenyuan Lu Wenbo Wang Zhengqu Chen Ling Liu Weixiao Lu Jiwen Key Laboratory for Precision and Non-traditional Machining Technology of the Ministry of Education Dalian University of Technology Dalian 116024 China AVIC Aerodynamics Research Institute Shenyang 110034 China

Aerodynamic parameters obtained from separation experiments of internal stores in a wind tunnel are significant in aircraft designs. Accurate wind tunnel tests can help to improve the release stability of the stores and in-flight safety of the aircrafts in supersonic environments.A simulative system for free drop experiments of internal stores based on a practical project is provided in this paper. The system contains a store release mechanism, a control system and an attitude measurement system. The release mechanism adopts a six-bar linkage driven by a cylinder, which ensures the release stability. The structure and initial aerodynamic parameters of the stores are also designed and adjusted. A high speed vision measurement system for high speed rolling targets is utilized to measure the pose parameters of the internal store models and an optimizing method for the coordinates of markers is presented based on a priori model. The experimental results show excellent repeatability of the system, and indicate that the position measurement precision is less than0.13 mm, and the attitude measurement precision for pitch and yaw angles is less than 0.126°, satisfying the requirements of practical wind tunnel tests. A separation experiment for the internal stores is also conducted in the FL-3 wind tunnel of China Aerodynamics Research Institute.

关键词： Binocular vision system Pose measurement release mechanism Wind tunnel

TOTAL PHOSPHORUS release FROM BOTTOM SEDIMENTS IN FLOWING WATER

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Journal of Hydrodynamics 2012年第4期24卷 589-594页

作者： ZHANG Kun CHENG Peng-da ZHONG Bao-chang WANG Dao-zeng Shanghai Institute of Applied Mathematics and Mechanics and Shanghai Key Laboratory of Mechanics in Energy Engineering Shanghai UniversityShanghai 200072China

In this paper, the bottom of the Dianshan Lake was selected as a test sample. The dynamic release of contaminated sediments into the overlying water column was experimentally investigated in an open water channel under different hydrodynamic conditions. The experimental results indicate that the Total Phosphorus （TP） release process can be divided into three stages： rapid release, slow release and equilibration release. In the initial release stage the measured TP concentration changes along the depth. The TP concentration near the sediment-water interface is higher than that near the water surface, but the TP concentration becomes uniform along the depth after 3 h. The dynamic release of re-suspension sediment pollutants is about 6 times higher than the static release of sediment-water interface. There are three main types of release mechanism： diffusion release, re-suspended pore water mixing release and re-suspended particles desorbing release.

关键词： Total Phosphorus (TP) concentration sediment re-suspension overlying-water release mechanism

Simulative technology for auxiliary fuel tank separation in a wind tunnel

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Chinese Journal of Aeronautics 2016年第3期29卷 608-616页

作者： Ma Xin Liu Wei Chen Ling Li Xiao Jia Zhenyuan Shang Zhiliang Key Laboratory for Precision and Non-traditional Machining Technology of the Ministry of Education Dalian University of Technology

In this paper, we propose a simulative experimental system in wind tunnel conditions lbr the separation of auxiliary fuel tanks from an aircraft. The experimental system consists of a simulative release mechanism, a scaled model and a pose measuring system. A new release mechanism was designed to ensure stability of the separation. Scaled models of the auxiliary fuel tank were designed and their moment of inertia was adjusted by installing counterweights inside the model. Pose param- eters of the scaled model were measured and calculated by a binocular vision system. Additionally, in order to achieve high brightness and high signal-to-noise ratio of the images in the dark enclosed wind tunnel, a new high-speed image acquisition method based on miniature self-emitting units was pre- sented. Accuracy of the pose measurement system and repeatability of the separation mechanism were verified in the laboratory. Results show that the position precision of the pose measurement system can reach 0.1 mm, the precision of the pitch and yaw angles is less than 0.1° and that of the roll angle can be up to 0.3°. Besides, repeatability errors of models＂ velocity and angular velocity controlled by the release mechanism remain small, satisfying the measurement requirements. Finally, experiments for the separation of auxiliary fuel tanks were conducted in the laboratory.

关键词： Aircraft auxiliary equipmentBinocular vision Position and attitude mea-surement release mechanism Simulation experiment

The development of sandwiched osmotic pump capsule for controlled release of Metformin Hydrochloride and Gliclazide

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The development of sandwiched osmotic pump capsule for contr...