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Rapid Green Synthesis of Silver Nanoparticles by reishi and Their Antibacterial Activity and Mechanisms

Journal of Biomaterials and Nanobiotechnology 2024年第3期15卷 51-63页

作者： Akamu J. Ewunkem T’nasia Priester Desia Williams Bailey Ariyon Ilunga Tshimanga Brittany Justice Dinesh K. Singh Department of Biological Sciences Winston-Salem State University Winston-Salem North Carolina USA

Nanotechnology is a rapidly growing field in biomedical engineering with references to efficiency, safety, and cost-effective approaches. Herein, the objective of this study was to examine an innovative approach to rapidly synthesis silver nanoparticles from an aqueous extract of medicinal mushroom Ganoderma lucidum (also known as reishi). The structural and dimensional dispersion of the biosynthesized silver nanoparticles from reishi was confirmed by UV-Vis spectrophotometer (UV-Vis) and Scanning Electron Microscopy (SEM) analysis. Additionally, the biosynthesized silver nanoparticles from resihi were used to explore their potential antimicrobial activity against Staphylococcus aureus and Micrococcus luteus and Escherichia coli and Klebsiella pneumoniae. The results from this study revealed that the silver nanoparticles mediated by reishi adopted a spherical shape morphology with sizes, less than 100 nm and revealed strong absorption plasmon band at 440 nm. Furthermore, the biosynthesized silver nanoparticles from reishi exhibited antibacterial activity against the tested S. aureus and M. luteus and E. coli and K. pneumoniae by altering their morphology which signifies their biomedical potential.

关键词： Nanotechnology reishi Nanoparticles Antimicrobial Green Synthesis

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reishi Mushroom Attenuates Hepatic Inflammation and Fibrosis Induced by Irradiation Enhanced Carbon Tetrachloride in Rat Model

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Journal of Biosciences and Medicines 2015年第10期3卷 24-38页

作者： Omama E. El Shawi Sahar S. Abd El-Rahman Marwa Abd El Hameed Health Radiation Research Department National Centre for Radiation Research and Technology Atomic Energy Authority Cairo Egypt Department of Pathology College of Veterinary Medicine Cairo University Drug Radiation Research Department National Centre for Radiation Research and Technology Atomic Energy Authority Cairo Egypt

This work was undertaken to establish a new experimental model of hepatic fibrosis by gamma irradiation and CCl4 and to study the hepatoprotective effect of reishi Mushroom (RM) against hepatic fibrosis induced in that model. Our results revealed that oral co-administration of 110 mg/kg RM by gavage to fibrotic rats offered an obvious hepatic protection as assured by the significant decrement in ALT and AST, HP content, MDA and NO levels with elevation of the antioxidant enzymes activities. The levels of TGF-β, TNF-α, HO-1 and type-1 collagen and their m-RNA expression were markedly declined as compared with those of fibrotic rats. Microscopical examination revealed that the exposure of rats to radiation aggravated the effect of CCl4 causing extensive collagen deposition and marked pseudolobulation of the hepatic parenchyma indicative of bridging fibrosis. While, oral co-administration of RM obviously improved the state of steatosis and apparently suppressed hepatic fibrogenesis.

关键词： Carbon Tetrachloride Gamma Irradiation Hepatic Fibrosis reishi Mushroom Rats

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“Ganoderma lucidum sensu lato”-a sacred mushroom for immortality

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Studies in Fungi 2020年第1期5卷 508-516页

作者： Ayesha P Maham A Ariza A Husnain H Faculty of Pharmacy University of LahoreLahorePakistan Faculty of Pharmacy University of Central PunjabLahorePakistan

Ganoderma lucidum sensu lato,is an ancient Chinese mushroom commonly known as“reishi”or“Linghzi”which has been used for nutritional and therapeutic *** is a basidiomycete widely distributed in temperate and tropical *** 2000 classes of reishi,only 6 types are commonly presented to be effective for therapeutic *** 6 types were known as black,red,blue,yellow,white and purple,*** constituents of reishi are Polysaccharides,Triterpenoids,Sterols and *** has been clinically used as immune system modulator,antiviral,cytotoxic agent,antibacterial,hepatoprotective,anti-inflammatory and also in the treatment of neurological *** wide clinical scope of reishi has influenced to name it in English with the nickname of“the mushroom of immortality”.

关键词： Linghzi Medicinal Mushroom reishi Therapeutic value

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Intraoperative Bleeding Associated with Preoperative Use of <i>Ganoderma lucidum</i>Supplements

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Open Journal of Anesthesiology 2014年第6期4卷 119-122页

作者： Steven Shulman Shelly Sharma Bernadette Cracchiolo Kesavan Shubhangi Anthony Sifonios Department of Anesthesiology Rutgers—New Jersey Medical School Newark USA Department of Obstetrics and Gynecology Rutgers—New Jersey Medical School Newark USA

reishi mushroom, also known as Ganoderma lucidum, is a type of edible medicinal fungi that is found throughout Asia. Recent research has shown that it may also have antiplatelet activity that is similar to aspirin. Likewise simvastatin has been shown to inhibit platelet aggregation. In addition, montelukast has anecdotally related to one case of acquired thrombopathia and may interfere with platelet aggregation. We report a case of intraoperative hemorrhage with laparoscopic trocar placement and dissection in a patient concomitantly taking Ganoderma lucidum supplements, simvastatin and montelukast. The hemorrhage only responded to a transfusion of platelets. We believe this is the first report associating Ganoderma lucidum products with an intraoperative hemorrhage. We recommend that patients who are on simvastatin, montelukast or an anticoagulant should refrain from taking Ganoderma lucidum products for seven days prior to surgery.

关键词： reishi Mushroom Ganoderma lucidium Simvastation Montelukast

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