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The Neurocognitive Assessment of HIV-Infected School-Aged Nigerian Children

World Journal of AIDS 2013年第2期3卷 124-130页

作者： Gbemisola O. Boyede Foluso E. A. Lesi Chinyere V. Ezeaka Charles S. Umeh Clinical Psychology Unit Department of Psychiatry Lagos University Teaching Hospital Lagos Nigeria Department of Paediatrics Lagos University Teaching Hospital Lagos Nigeria Division of Developmental Paediatrics School and Child and Adolescent Health Red Cross War Memorial Children’s Hospital University of Cape Town Cape Town South Africa

Objective: Studies available on cognitive function among school-aged HIV-infected African and in particular Nigerian children are few. The purpose of the study was to assess the neurocognitive function of a group of HIV-infected schoolaged (6 - 15 years) children using the Raven’s Standard Progressive Matrices (RPM). Method: Cognitive assessments of 69 HIV positive children and 69 age- and sex-matched apparently healthy HIV negative control children were performed using the Raven’s Standard Progressive Matrices (RPM). The children were subdivided (Piaget’s developmental staging) into two sub-groups: the concrete operation stage (6 - 11 years) and the formal operation stage (12 - 15 years) for analysis. Result: The mean RPM score for the HIV positive children was 18.2 (8.0 - 47.0, SD 9.8) which was significantly lower than the score of 27.2 (8.0 - 52.0, SD 13.8) for the HIV negative children (p < 0.001). On the RPM grading and using the HIV negative children as the standard, 56.5% of the HIV positive children had cognitive performance at below average to intellectually defective range. Conclusion: School-aged HIV positive children had significantly lower cognitive scores compared with age and gender-matched HIV negative children. Routine neuropsychological evaluation of all school-aged HIV-infected children is recommended. Early detection of cognitive impairment will help in planning appropriate interventions.

关键词： Pediatric HIV Cognitive Assessment School-Age Children ravens Progressive Matrices Nigeria

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