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黄牛杂志 2002年第2期28卷 27-29页

作者：樊斌刘榜李奎华中农业大学畜牧兽医学院动物分子生物学与育种实验室湖北武汉430070

随机扩增微卫星 DNA多态标记是在微卫星 DNA基础上衍生出的一种新型分子标记。它综合了微卫星 DNA和随机扩增多态 DNA( RAPD)两种标记的优点 ,可用来快速检测动植物群体的遗传变异及分离新的微卫星 DNA。本文介绍了随机扩增微卫星 DNA... 详细信息

随机扩增微卫星 DNA多态标记是在微卫星 DNA基础上衍生出的一种新型分子标记。它综合了微卫星 DNA和随机扩增多态 DNA( RAPD)两种标记的优点 ,可用来快速检测动植物群体的遗传变异及分离新的微卫星 DNA。本文介绍了随机扩增微卫星 DNA多态标记的种类及其应用。

关键词：应用随机扩增微卫星DNA多态标记 ramps 种类分子标记

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Regulation of neuroimmune processes by damage-and resolution-associated molecular patterns

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Neural Regeneration Research 2021年第3期16卷 423-429页

作者： Andis Klegeris Department of Biology University of British Columbia Okanagan CampusKelownaBCCanada

Sterile inflammatory processes are essential for the maintenance of central nervous system homeostasis,but they also contribute to various neurological disorders,including neurotrauma,stroke,and demyelinating or neurodegenerative *** mechanisms in the central nervous system and periphery are regulated by a diverse group of endogenous proteins,which can be broadly divided into the pro-inflammatory damageassociated molecular patterns(DAMPs)and anti-inflammatory resolution-associated molecular patterns(ramps),even though there is notable overlap between the DAMPand RAMP-like activities for some of these *** groups of molecular patterns were initially described in peripheral immune processes and pathologies;however,it is now evident that at least some,if not all,of these immunomodulators also regulate neuroimmune processes and contribute to neuroinflammation in diverse central nervous system *** review of recent literature demonstrates that studies on DAMPs and ramps of the central nervous system still lag behind the much broader research effort focused on their peripheral ***,this review also reveals that over the last five years,significant advances have been made in our understanding of the neuroimmune functions of several well-established DAMPs,including high-mobility group box 1 protein and interleukin *** neuroimmune functions have been demonstrated for other DAMPs that previously were considered almost exclusively as peripheral immune regulators;they include mitochondrial transcription factor A and cytochrome *** of the central nervous system are an emerging area of neuroimmunology with very high translational potential since some of these molecules have already been used in preclinical and clinical studies as candidate therapeutic agents for inflammatory conditions,such as multiple sclerosis and rheumatoid *** therapeutic potential of DAMP antagonists and neutralizing antibodies in central

关键词： Alzheimer's disease astrocytes DAMPs HMGB1 microglia neurodegeneration neuroimmune responses neuroinflammation neurotrauma oligodendrocytes pattern-recognition receptors ramps

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Effect of ramp-cavity on hydrogen fueled scramjet combustor

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Propulsion and Power Research 2014年第1期3卷 22-28页

作者： J.V.S.Moorthy B.Rajinikanth B.V.N.Charyulu G.Amba Prasad Rao Scientist Defence Research and Development LaboratoryHyderabadAndhra Pradesh 500058India Professor in Mechanical Engineering National Institute of TechnologyWarangalAndhra Pradesh 506004India

Sustained combustion and optimization of combustor are the two challenges being faced by combustion scientists working in the area of supersonic *** mixing,lower stagnation pressure losses,positive thrust and sustained combustion are the key issues in the field of supersonic *** fluid mechanism is required to achieve good *** induce such mechanisms in supersonic inflows,the fuel injectors should be critically shaped incurring less flow *** investigations are focused on the effect of fuel injection scheme on a model scramjet combustor *** at supersonic flow generate axial vortices that help in macro-mixing of fuel with *** of shocks generated by ramps with the fuel stream generates boro-clinic torque at the air&liquid fuel interface,enhancing *** zones present in cavities increase the residence time of the combustible *** use of the advantageous features of both,a ramp-cavity combustor is *** combustor has two ***,constant height section consists of a backward facing step followed by ramps and cavities on both the top and bottom *** ramps are located alternately on top and bottom *** complete combustor width is utilized for the *** second section of the combustor is diverging area *** is provided to avoid thermal *** the present work gaseous hydrogen is considered as *** study was mainly focused on the mixing different fuel injection *** was found that injecting fuel upstream of the ramp was beneficial from fuel spread point of view.

关键词： Supersonic combustion Combustion instabilities ramps Cavities Mixing

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腹腔镜结肠下肠系膜上动脉先行根治性顺行模块化胰脾切除的初步探索

腹腔镜结肠下肠系膜上动脉先行根治性顺行模块化胰脾切除的初步探...

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2018年浙江省外科学学术年会

作者：张宇华金丽明吴嘉张成武胡智明浙江省人民医院肝胆胰、微创外科

目的 :探讨腹腔镜结肠下动脉先行入路根治性顺行模块化胰脾切除(ramps)治疗胰腺癌的可行性和远近期疗效。方法 :收集浙江省人民医院肝胆胰、微创外科自2017年9月至2018年6月行腹腔镜结肠下动脉先行入路ramps的3例患者的病历资料。回顾... 详细信息

目的 :探讨腹腔镜结肠下动脉先行入路根治性顺行模块化胰脾切除(ramps)治疗胰腺癌的可行性和远近期疗效。方法 :收集浙江省人民医院肝胆胰、微创外科自2017年9月至2018年6月行腹腔镜结肠下动脉先行入路ramps的3例患者的病历资料。回顾性分析其远近期疗效。结果 :3例患者术前诊断:胰体尾肿瘤,行腹腔镜下ramps,均采用结肠下动脉先行入路,无中转开放手术。手术时间260,280,320min。术中出血100,100,300ml。术后住院10,10,18d。术后无再次手术,无腹腔内出血、消化道出血、乳糜漏,胃瘫等并发症,无围手术期死亡。术后一例患者出现生化漏。术后病理均为胰腺导管腺癌,肿瘤直径:(2.5,2.5,3cm),胰颈切缘阴性,淋巴结(0/8,1/10,0/10)。随访至2018年8月,无复发。结论 :胰体尾部癌,行腹腔镜结肠下动脉先行入路ramps是安全可靠的,可以预先判断可切除性,增加肿瘤切除的彻底性,值得推广。

关键词：腹腔镜 ramps 动脉优先肠系膜上动脉胰腺癌

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