检索结果-南通市图书馆

检索条件"主题词=RT1B"

共 1 条记录，以下是1-10 订阅

全选清除本页清除全部题录导出标记到"检索档案"

详细简洁

排序：

The major histocompatibility complex genes were associated with the painrelated responses induced by formalin between DA and congenic DA.1U rats

The major histocompatibility complex genes were associated w...

引用

中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Yuan GUO~1,Fan-Rong YAO~1,Dong-Yuan CAO~(1,2),Rong LUO~1,Li LI~1,Shao-Jie MA~1,Hui-Sheng WANG~1,Yan ZHAO~(1*) 1 Department of Physiology and Pathophysiology,Xi''an Jiaotong University School of Medicine,Xi''an,710061,China 2 Palmer Center for Chiropractic Research,Palmer College of Chiropractic,741 brady Street,Davenport,I A 52803, USA

＜正＞Objective Some studies on humans,as well as laboratory animals suggested that there exist significant differences of pain-related response between *** in genetic influences on pain-related responses has increased dramatically in recent *** the present study,the role of major histocompability complex（MHC） genes in the pain-related responses induced by formalin was investigated in Dark-Agouti（DA） rats and a novel congenic DA.1U rats, whose genetic background is the same as DA rats except MHC *** behaviors were simultaneously analyzed for lh and the specific nociceptive scores were measured using the method described by Dubuisson and Dennis（1977） following intraplantar injection of formalin（2.5%,50μL）.The discharge rates of single afferent fiber innervating the planta of hindpaw were recorded from dorsal root to investigate the response induced by *** methods were used to observe the expression of rt1b,which represented the DQ region of MHC II genes,in L4/5 spinal cord in the two rat strains to analyze the role of MHC genes in the pain-related ***（1） biophasic pain-related responses were observed in the two strains following the intraplanta injection of *** specific nociceptive scores of DA rats in the two phases were significantly higher than those of DA.1U rats（P＜0.01）.（2） Electrophysiological results showed that the discharge rates of C and A8 fibers increased significantly in the two strains,and the mean net change of discharge rates of DA rats were significantly higher than that of DA.1U rats（P＜0.05）.（3） The expressions of rt1b were mainly observed in laminaeⅠ-Ⅱof L4/5 spinal cord in two *** expressions of rt1b in DA rats were significantly higher than those in DA.1U rats before and after injection of formahn（P＜0.05）.All these results suggested that DQ region of MHCⅡgenes may be involved in the pain-related response induced by formalin,which may provide further evidence for

关键词： major histocompability complex pain-related response individual difference rt1b

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

全选清除本页清除全部题录导出标记到“检索档案”

共1页 << < 1 > >>

回到顶部

执行限定条件

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：