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Favipiravir:a promising investigational agent in preventing infection and progression of COVID-19

Clinical Research Communications 2022年第1期5卷 33-40页

作者： Sidharth Mehta Himanshi Tanwar Pooja Rani Department of Pharmaceutical Sciences Guru Jambheshwar University of Science and TechnologyHisar-125001HaryanaIndia

In late Dec.2019,a huge number of pneumonia cases caused by novel coronavirus were reported in China.2019-nCoV pandemic has influenced on millions of people's life across the *** novel coronavirus was identified to be similar with MERS and ***,researchers and academicians across the world still trying to find out vaccines,new drug molecules against *** principle point of this review article is to explain the activity of favipiravir in preventing *** view of constrained data available in the literature,we specify that favipiravir treatment,among all other anti-viral drugs,accompanied by oxygen inhalation therapy,maintaining fluid and electrolyte balance,and nutritional support may be helpful in fighting *** were done on already approved existing anti-viral drugs for treating ebola virus,influenza virus infection and many such anti-viral agents like favipiravir,ritonavir,remdesivir,ribavirin,oseltamivir shows promising results in preventing COVID-19 infection and their clinical trials are currently undergoing in order to discover proper treatment of *** the aforementioned drug candidates,a broad-spectrum rna polymerase inhibitor favipiravir,which demonstrated a promising tolerance profile and anti-viral efficacy in patients having COVID-19 manifestations.

关键词： antiviral drugs clinical trial coronavirus COVID-19 favipiravir rna polymerase inhibitor SARS-CoV-2

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