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Safety and efficacy of a novel abluminal groove-filled biodegradablepolymer sirolimus-eluting stent for the treatment of de novo coronarylesions： 12-month results from the TARGET II trial

引用

Chinese Medical Journal 2014年第6期127卷 1027-1032页

作者： Xu Bo Zhao Yelin Yang Yuejin Zhang Ruiyan Li Hui Ma Changsheng Chen Shaoliang Department of Cardiology Fu Wai Hospital National Center for Cardiovascular Diseases Beijing 100037 China Department of Cardiology Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Department of Cardiology Daqing Oil Field General HospitalDaqing Heilongjiang 163114 China Department of Cardiology Affiliated Anzhen Hospital of Capital Medical University Beijing 100029 China Department of Cardiology Nanjing First Hospital Nanjing Medical University Nanjing Jiangsu 210006 China

Background In the TARGET I randomized controlled trial, the novel abluminal groove-filled biodegradable polymersirolimus-eluting stent FIREHAWK proved non-inferior to the everolimus-eluting stent in nine-month in-stent late loss insingle de novo coronary lesions. This study was aimed at evaluating clinical safety and effectiveness of FIREHAWK in amoderately complex population （including patients with small vessels, long lesions and multi-vessels）, and at validatingthe ability of the SYNTAX score （SS） to predict clinical outcomes in patients treated with this latest generation drug-elutingstent.

关键词： 5-YEAR FOLLOW-UP ARTERY-DISEASE CLINICAL-EVALUATION randomized-trials VESSEL SIZE INTERVENTION EVEROLIMUS OUTCOMES COHORT REVASCULARIZATION

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Should primary percutaneous coronary intervention be always the first option for patients with an ST elevation myocardial infarction？

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Chinese Medical Journal 2010年第11期123卷 1363-1364页

作者： LI Jian-ping HUO Yong Department of Cardiology Peking University First HospitalBeijing 100034 China

Acute ST elevation myocardial infarction, caused by the acute occlusion of a coronary artery, is a lifethreating emergency. Reperfusion therapy, namely, using the mechanical or chemical method to open the infarction related artery （IRA）, has become the key treatment for such patients. As the duration of a coronary occlusion is the main determinant of final infarct size, and the latter determines the outcome of acute myocardial infarction （AMI） patients, the time issue has long been the most important topic in reperfusion therapy. Besides the time issue, several other factors must be considered： the efficiency of the reperfusion therapy, and the availability of the reperfusion therapy.

关键词： randomized-trials THROMBOLYTIC THERAPY ANGIOPLASTY

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Current status of coronary artery bypass surgery

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Chinese Medical Journal 2009年第2期122卷 126-128页

作者： CHEN Xin Department of Thoracic and Cardiovascular Surgery Nanjing First Hospital Affiliated to Nanjing Medical University Nanjing Jiangsu 210006 China

Surgical revascularization for atherosclerotic heart disease, also called coronary artery bypass grafting （CABG）, was first performed in 1962, and is one of the great achievements in medicine. Relief of angina, improvement of exercise tolerance, and the realization of survival benefit have been documented. CABG has been used in multi-vessel disease and left main stenosis for over 40 years. In the last two decades the mortality of CABG has decreased to less than 2% despite an aging population with increased risk factors. However, percutaneous coronary intervention （PCI）, especially with drug-eluting stents, has been challenging CABG. While PCI has improved, CABG has also progressed with better peri-operative management,

关键词： INTERNAL THORACIC ARTERY OFF-PUMP randomized-trials CLINICAL-OUTCOMES VESSEL DISEASE REVASCULARIZATION CONDUIT PATENCY

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