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Demand for longer quarantine period among common and uncommon COVID-19 infections: a scoping review

Infectious Diseases of Poverty 2021年第2期10卷 5-13页

作者： Zhi-Yao Li Yu Zhang Liu-Qing Peng Rong-Rong Gao Jia-Rui Jing Jia-Le Wang Bin-Zhi Ren Jian-Guo Xu Tong Wang Department of Health Statistics and Epidemiology School of Public HealthCollaborative Innovation Center of Reverse Microbial EtiologyShanxi Medical University56 Xinjiannanlu StreetYingze DistrictTaiyuan 030001ShanxiPeople's Republic of China Shanxi Provincial Center for Disease Control and Prevention Taiyuan 030001People's Republic of China Shanxi Provincial Key Laboratory o f Major Infectious Disease Pandemic Response Taiyuan 030001People's Republic of China State Key Laboratory of Infectious Disease Prevention and Control National Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206People’s Republic of China In stitu te of Public Health Nankai UniversityTianjing 300350People’s Republic of China.

Background:As one of the non-pharmacological interventions to control the transmission of COVID-19,determining the quarantine duration is mainly based on the accurate estimates of the incubation ***,patients with coarse information of the exposure date,as well as infections other than the symptomatic,were not taken into account in previously published ***,by using the statistical method dealing with the interval-censored data,we assessed the quarantine duration for both common and uncommon *** latter type includes the presymptomatic,the asymptomatic and the recurrent test positive ***:As of 10 December 2020,information on cases have been collected from the English and Chinese databases,including Pubmed,Google scholar,CNKI(China National Knowledge Infrastructure)and *** websites and medias were also searched as data *** data were transformed into doubly interval-censored and the accelerated failure time model was *** estimating the incubation period and the time-to-event distribution of worldwide COVID-19 patients,we obtain the large percentiles for determining and suggesting the quarantine *** symptomatic and presymptomatic COVID-19 patients,the incubation time is the duration from exposure to symptom *** the asymptomatic,we substitute the date of first positive result of nucleic acid testing for that of symptom ***,the time from hospital discharge or getting negative test result to the positive recurrence has been calculated for recurrent positive ***:A total of 1920 laboratory confirmed COVID-19 cases were *** all uncommon infections,34.1%(n=55)of them developed symptoms or were identified beyond fourteen *** on all collected cases,the 95th and 99th percentiles were estimated to be 16.2 days(95%Cl 15.5-17.0)and 22.9 days(21.7-24.3)***,we got similar estimates based on merely symptomatic and presymptomatic infections a

关键词： COVID-19 quarantine duration Incubation period Asymptomatic infections Presymptomatic infection Recurrent positive

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COVID-19 patient with an incubation period of 27 d:A case report

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World Journal of Clinical Cases 2021年第21期9卷 5955-5962页

作者： Xue Du Yang Gao Kai Kang Yang Chong Mei-Ling Zhang Wei Yang Chang-Song Wang Xiang-Lin Meng Dong-Sheng Fei Qing-Qing Dai Ming-Yan Zhao Department of Critical Care Medicine The First Affiliated Hospital of Harbin Medical UniversityHarbin 150001Heilongjiang ProvinceChina Department of Critical Care Medicine The Sixth Affiliated Hospital of Harbin Medical UniversityHarbin 150028Heilongjiang ProvinceChina Institute of Critical Care Medicine The Sino Russian Medical Research Center of Harbin Medical UniversityHarbin 150081Heilongjiang ProvinceChina Department of Critical Care Medicine The Harbin Medical University Cancer HospitalHarbin 150081Heilongjiang ProvinceChina Department of Critical Care Medicine The Second Affiliated Hospital of Harbin Medical UniversityHarbin 150086Heilongjiang ProvinceChina

BACKGROUND As a highly contagious disease,coronavirus disease 2019(COVID-19)is wreaking havoc around the world due to continuous spread among close contacts mainly via droplets,aerosols,contaminated hands or ***,centralized isolation of close contacts and suspected patients is an important measure to prevent the transmission of *** present,the quarantine duration in most countries is 14 d due to the fact that the incubation period of severe acute respiratory syndrome coronavirus type 2(SARS-CoV-2)is usually identified as 1-14 d with median estimate of 4-7.5 *** COVID-19 patients in the incubation period are also contagious,cases with an incubation period of more than 14 d need to be *** SUMMARY A 70-year-old male patient was admitted to the Department of Respiratory Medicine of The First Affiliated Hospital of Harbin Medical University on April 5 due to a cough with sputum and shortness of *** April 10,the patient was transferred to the Fever Clinic for further treatment due to close contact to one confirmed COVID-19 patient in the same *** the period from April 10 to May 6,nucleic acid and antibodies to SARS-CoV-2 were tested 7 and 4 times,respectively,all of which were *** May 7,the patient developed fever with a maximum temperature of 39℃,and his respiratory difficulties had *** results of nucleic acid and antibody detection of SARS-CoV-2 were *** May 8,the nucleic acid and antibody detection of SARS-CoV-2 by Heilongjiang Provincial Center for Disease Control were also positive,and the patient was diagnosed with COVID-19 and reported to the Chinese Center for Disease Control and *** This case highlights the importance of the SARS-CoV-2 incubation *** epidemiological investigations and clinical observations are urgently needed to identify the optimal incubation period of SARS-CoV-2 and formulate rational and evidence-based quarantine policies for COVID-19

关键词： COVID-19 Incubation period quarantine duration SARS-CoV-2 Case report

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