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urine microscopy and neutrophilelymphocyte ratio are early predictors of acute kidney injury in patients with urinary tract infection

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Asian Journal of Urology 2021年第2期8卷 220-226页

作者： Sreerag Kana Rajesh Nachiappa Ganesh Deepanjali Surendran Rajendra G.Kulkarni Ravi Kishore Bobbili Jose Olickal Jeby Department of Pathology Jawaharlal Institute of Postgraduate Medical Education and ResearchPuducherryIndia Department of Medicine Jawaharlal Institute of Postgraduate Medical Education and ResearchPuducherryIndia Department of Immunohaematology and Transfusion Medicine Jawaharlal Institute of Postgraduate Medical Education and ResearchPuducherryIndia Department of Preventive and Social Medicine Jawaharlal Institute of Postgraduate Medical Education and ResearchPuducherryIndia

Objective:Urinary tract infection(UTI)is a common cause of morbidity and hospitalisation in the population *** UTI is indolent and causes subclinical acute kidney injury(AKI)resulting in preventable cause of scarring of renal *** explored urinary and serum levels of kidney injury molecule-1(KIM-1),haematological parameters and quantitative urine microscopy parameters to predict kidney ***:Neutrophilelymphocyte ratio(NLR)is obtained by dividing absolute neutrophil count with absolute lymphocyte *** urine sediment microscopy was performed and correlated with clinical,biochemical and haematological findings to predict AKI in patients with *** ELISA was performed for serum and urine levels of *** two adult patients with UTI were enrolled,45 of whom had AKI while 27 were in the non-AKI ***:NLR(p=0.005)and renal tubular epithelial cell-granular cast score in quantitative urine microscopy(p=0.008)are strong predictors of AKI in patients with UTI while rest of quantitative urine microscopy parameters and serum and urinary levels of KIM-1 molecule were not found to be useful in prediction of ***:NLR in haemogram is a novel and useful biomarker for predicting AKI in patients with UTI.

关键词： Acute kidney injury kidney injury molecule-1 Neutrophil elymphocyte ratio quantitative urine microscopy score Urinary tract infection

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