检索结果-南通市图书馆

Effects of SARS-CoV-2 infection on neuroimaging and neurobehavior in neonates

World Journal of Pediatrics 2021年第2期17卷 171-179页

作者： Kai Yan Fei-Fan Xiao Yu-Wei Jiang Tian-Tian Xiao Da-Jiang Zhang Wen-Hao Yuan Jian-Bo Shao Guo-Qiang Cheng Ling-Kong Zeng Department of Neonatology Children’s Hospital of Fudan UniversityNational Children's Medical CenterShanghaiChina Key Laboratory of Neonatal Diseases of Ministry of Health ShanghaiChina Center for Molecular Medicine Children's Hospital of Fudan UniversityNational Children’s Medical CenterInstitutes of Biomedical SciencesFudan UniversityShanghai.China Institute of Neuroscience Key Laboratory of Primate NeurobiologyCAS Center for Excellence in Brain Science and Intelligence TechnologyChinese Academy of SciencesShanghaiChina Department of Neonatology Chengdu Women's and Children’s Central HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengduChina Department of Radiology Children’s Hospital of Fudan UniversityNational Children's Medical CenterShanghaiChina Department of Neonatology Wuhan Children's Hospital(Wuhan Maternal and Child Healthcare Hospital)Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Department of Radiology Wuhan Children's Hospital(Wuhan Maternal and Child Healthcare Hospital)Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina

Background We collected neonatal neurological,clinical,and imaging data to study the neurological manifestations and imaging characteristics of neonates with coronavirus disease 2019(COVID-19).Methods This case-control study included newborns diagnosed with COVID-19 in Wuhan,China from January 2020 to July *** included newborns had complete neurological evaluations and head magnetic resonance *** normalized the extracted T2-weighted imaging data to a standard neonate template space,and segmented them into gray matter,white matter,and cerebrospinal *** comparison of gray matter volume was conducted between the two *** A total of five neonates with COVID-19 were included in this *** median reflex scores were 2 points lower in the infected group than in the control group(P=0.0094),and the median orientation and behavior scores were 2.5 points lower in the infected group than in the control group(P=0.0008).There were also significant differences between the two groups in the total scale score(P=0.0426).The caudate nucleus,parahippocampal gyrus,and thalamus had the strongest correlations with the Hammersmith neonatal neurologic examination(HNNE)score,and the absolute correlation coefficients between the gray matter volumes and each part of the HNNE score were all almost greater than *** We first compared the neurological performance of neonates with and without COVID-19 by quantitative neuroimaging and neurological examination *** the limited numbers of patients,more studies focusing on the structural or functional aspects of the virus in the central nervous system in different age groups will be carried out in the future.

关键词： Coronavirus disease 2019 Magnetic resonance imaging Neonates quantitative neuroimaging Severe acute respiratory syndrome coronavirus 2

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：