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Efficacy evaluation of summer acupoint application treatment on asthma patients: a two-year follow-up clinical study

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Journal of Traditional Chinese Medicine 2015年第1期35卷 21-27页

作者： Wu Xiaqiu Peng Jin Li Guoqin Zhang Wei Liu Guangxia Liu Baoyan Department of Preventive Medicine Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical Science Department of Respiratory Guanganmen Hospital China Academy of Chinese Medical Science Department of Acupuncture and Massage The First Hospital of Hunan University of Chinese Medicine Department of Acupuncture The Second Hospital of Anhui University of Chinese Medicine China Academy of Chinese Medical Science

OBJECTIVE: To evaluate the self-efficacy and satisfaction of asthma patients subjected to summer acupoint application treatment(SAAT).METHODS: A two-year follow-up clinical study was conducted. Patients with asthma were treated by applying a herbal paste onto the Feishu(BL 13) and Fengmen(BL 12) acupoints on the three hottest days of summer, according to the traditional Chinese calendar, from 2008 to 2010. During a two-year follow-up, these patients were asked tofill out a questionnaire evaluating asthma degree,exacerbation frequency, concomitant medications and self-satisfaction. The self-rate and doctor-report outcomes obtained in parallel were evaluated to assess the efficacy of ***: A total of 527 asthma patients were initially enrolled in this study, of which 97 elderly patients and those with more severe cases of asthma were lost to follow-up. Thus, a total of 430 patients were valid for analysis using self-rate data. Nevertheless, occasional negative returns were obtained;almost all of the outcomes were rated as "No change", "Moderate effective", or "Very effective". In addition, 80% of the patients were satisfied with this treatment. Moreover, 391(91.4%) patients were somewhat improved after SAAT in 2009, and further improvement was observed in 2010. After SAAT, the average asthma-degree score decreased from 5.3 in 2008 to 4 in 2009 and, subsequently to3.5 in ***: With pronounced patient satisfaction, SAAT can reduce the exacerbation severity and frequency, concomitant medications and asthma degree. Prolonging the treatment course might enhance the efficacy of SAAT.

关键词： Acupoint sticking therapy quality oflife Self efficacy Asthma Chinese medicine, traditional

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Different faces of gastroparesis

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World Journal of Gastroenterology 2009年第48期15卷 6052-6060页

作者： Klaus Bielefeldt Naeem Raza Susan L Zickmund Division of Gastroenterology University of Pittsburgh Medical Center Center of Health Equity Research and Practice at the Veteran Administration Health System Pittsburgh

AIM： To test the hypothesis that pain and affect rather than impaired emptying determine symptom severity in patients with gastroparesis. METHODS： Adult patients with documented gastroparesis were enrolled prospectively in a single center and asked to complete the Gastroparesis Cardinal Symptom Index （GCSt）, Hospital Anxiety and Depression Scale （HADS）, the Short Form 12 （SF-12） as quality of life index, rate pain severity and answer 10 open-ended questions. RESULTS： A total of 55 patients （44 women） participated. Idiopathic （n = 29） or diabetic （n = 11） gastroparesis and connective tissue disease （n = 8） were the most common underlying causes. Antiemetics （n = 30） and prokinetics （n = 32） were most often prescribed. Seventeen patients used opioids on a daily basis. Nausea and/or vomiting （n = 28）, pain （n = 24） and bloating （n = 14） were most commonly listed as dominant symptoms. Patients subjectively attributed symptom improvement to nutritional and dietary therapy （n= 11）, prokinetics （n = 11）, antiemetics （n = 10） or analgesic agents （n = 3）. In univariate analyses, the physical subscore of the SF-12 and HADS, but not gastric emptying delay or symptom duration significantly correlated with disease severity as measured by the GCSI. In multivariate analyses, the combination of vomiting, bloating and depression best predicted the overall impact on quality of life. CONCLUSION： The study confirms the importance of pain and affect in gastroparesis, which requires novel approaches to improve more effectively the quality of life in patients with this disorder.

关键词： Pain Depression Gastroparesis quality oflife

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The quality of Life of Chinese Middle-Aged Male Patients with Gastric Carcinoma After Total Gastrectomy and Nursing Intervention

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Clinical oncology and cancer researeh 2010年第2期7卷 151-156页

作者： Yan WANG Hui-ying WANG Guo-hong YIN Hui-zi TIAN Dan WANG Department of Gastroenterological Cancer Tianjin Medical University Cancer Institute and Hospital Tianjin 300060 China.

OBJECTIVE The purpose of this study was to evaluate the quality of life （QOL） in Chinese middle-aged male patients with gastric carcinoma after total gastrectomy, to investigate the factors affecting their QOL, and to Study the effectiveness of nursing *** Structured questionnaire （EORTC QLQ-C30） was used among 162 middle-aged male patients after total gastrectomy （the patients finished the whole process of chemotherapy, and returned home, and society） for data collection and reevaluate the patients＇ aualitv of life with 2 months nursing *** The patient＇s quality of life was related to their education level, economic condition, family support, and pathological staging. This study showed that patients got higher scores in Functional scales （except for CF）, and lower scores in Symptom scales and single items （except for FI） after receiving intervention than before it was received *** The study revealed that the QOL in middleaged male patients after total gastrectomy was worse when there was inadequate attention. After implementing pertinent nursing intervention implementing, patients＇ mental attitude and negative behavior were improved, and their QOL was enhanced after returning home and into society.

关键词： middle-aged patients gastrectomy quality oflife nursing.

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Neurosurgery in Parkinson's disease:Social adjustment, quality of life and coping strategies

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Neural Regeneration Research 2013年第30期8卷 2856-2867页

作者： Meyer Mylène Montel Sébastien Colnat-Coulbois Sophie Lerond Jérme Potheegadoo Jevita Vidailhet Pierre Gospodaru Nicolaie Vespignani Hervé Barroche Gérard Spitz Elisabeth Schwan Raymund Lorraine University Department of Neurology University Hospital INSERM Clinical Investigation Center 9501 Department of Health Psychology EPSAM Department of Neurosurgery University Hospital Psychotherapic Center of Nancy INSERM 666 Unit University Hospital Care Support and Prevention Center in Addiction University Hospital

Subthalamic nucleus deep brain stimulation has become a standard neurosurgical therapy for ad- vanced Parkinson＇s disease. Subthalamic nucleus deep brain stimulation can dramatically improve the motor symptoms of carefully selected patients with this disease. Surprisingly, some specific dimensions of quality of life, ＂psychological＂ aspects and social adjustment do not always improve, and they could sometimes be even worse. Patients and their families should fully understand that subthalamic nucleus deep brain stimulation can alter the motor status and time is needed to readapt to their new postoperative state and lifestyles. This paper reviews the literatures regarding effects of bilateral subthalamic nucleus deep brain stimulation on social adjustment, quality of life and coping strategies in patients with Parkinson＇s disease. The findings may help to understand the psychoso-cial maladjustment and poor improvement in quality of life in some Parkinson＇s disease patients.

关键词： neural regeneration Parkinson's disease subthalamic nucleus deep brain stimulation quality oflife coping social adjustment reviews neurodegenerative diseases

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Comparison of presentation and impact on quality of life of gastroesophageal reflux disease between young and old adults in a Chinese population

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World Journal of Gastroenterology 2011年第41期17卷 4614-4618页

作者： Shou-Wu Lee Chia-Ming Chang Chi-Sen Chang Ai-Wen Kao Ming-Chih Chou Institute of Medicine Chung Shan Medical University Division of Gastroenterology Department of Internal MedicineTaichung Veterans General Hospital Department of Medicine Chung Shan Medical University Institute of Gerontology National Cheng Kang University Division of Geriatrics Department of Internal MedicineNational Cheng Kang University Hospital Division of Gastroenterology Department of Internal MedicineNational Cheng Kang University Hospital

AIM:To compare the presentation and impact on qual-ity of life of gastroesophageal reflux disease(GERD)in old and young age ***:Data from adult patients with GERD di-agnosed by endoscopic and symptomic characteristics were collected between January and November *** criteria included combined peptic ulcers,ma-lignancy,prior surgery,antacid medication for more than 2 mo,and *** patients were assigned to the elderly group if they were 65 years or older,or the younger group if they were under 65 *** had completed the GERD impact scale,the Chinese GERD questionnaire,and the SF-36 *** from other cases without endoscopic f ind-ings or symptoms were collected and these subjects comprised the control group in our ***:There were 111 patients with GERD and 44 normal cases:78(70.3%)and 33 patients(29.7%)were in the younger and elderly groups,*** were more female patients(60.3%)in the younger group,and more males(72.7%)in the elderly *** younger cases had more severe and fre-quent typical symptoms than the elderly ***-nif icantly more impairment of daily activities was noted in the younger patients compared with the elderly group,except for physical ***:Elderly patients with GERD were pre-dominantly male with rare presentation of typical symp-toms,and had less impaired quality of life compared with younger patients in a Chinese population.

关键词： Gastroesophageal reflux disease quality oflife Age factors

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Effect of Feitai Capsule(肺泰胶囊) on quality of Life and Progression-Free Survival of Patients with Unresectable Non-Small Cell Lung Cancer

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Chinese Journal of Integrative Medicine 2012年第2期18卷 106-111页

作者：余宗阳刘志臻欧阳学农杜建戴西湖陈曦赵忠全王文武李捷 Department of Oncology Fuzhou General HospitalNanjing Military Command Fujian Academy of Integrative Medicine Fujian University of Traditional Chinese Medicine

Objective： To examine the effect of a Chinese medicinal herbal formula （Feitai Capsule, 肺泰胶囊） on the quality of life （QOL） and progression-free survival （PFS） of patients with unresectable non-small cell lung cancer （NSCLC）. Methods： Sixty-two patients were randomly divided into the treatment group （31 cases） and the control group （31 cases）. For the treatment group, 4 capsules （1.2 g/capsule） of Feitai Capsule were administered 3 times a day after meals for 3 weeks; then no drug was administered for 1 week. This schedule was continued for at least 3 more cycles （12 weeks totally）. If there were no obvious toxic reactions, the treatment was extended. The patients were evaluated at least once every 8 weeks until progressive dJsease （PD）. For the control group, the regular follow-up and evaluation were performed at least once every 8 weeks until PD. Clinical symptoms, objective response, physical constitution and energy, QOL, and PFS were evaluated regularly. Analysis of variance （ANOVA）, a non-parametric test, and analysis of covariance were used to compare clinical features, amelioration of clinical symptoms, physical constitution and energy, and QOL. Kaplan- Meier analysis was used to compare the two-group PFS. Results： Sixty patients finished the final evaluation, with 30 patients in each group. Baseline characters between groups were not significantly different （P〉0.05）. The control group had a 36.7% improvement in clinical symptoms, while the treatment group had a 73.3% improvement. This difference was statistically significant （Z=-2.632, P=0.008）. The control group had a 26.7% improvement in the Karnofsky performance status （KPS）, while the treatment group had a 53.4% improvement. This was also significantly different （Z=-2.182, P=0.029）. A comparative analysis indicated a positive correlation （r=0.917, P〈0.001）. Compared with the control group, QOL in the treatment group was significantly improved, except in the social/family condition and doctor-patient relat

关键词： non-small cell Lung cancer Chinese medicine Feitai Capsule maintenance treatment quality oflife progression-free survival

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