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Study on effect of Traditional Chinese Medicine Jianpi Chushi decoction and ointment on chronic eczema

Asian Pacific Journal of Tropical Medicine 2016年第9期9卷 897-900页

作者： Hui-Lei Wan Hui-Zhi Chen Xiu-Qin Shi Department of Medical Affairs People's Hospital of Zhengzhou Department of Clinical Laboratory the First Affiliated Hospital of Zhengzhou University Department of Pharmacy the First Affiliated Hospital of Zhengzhou University

Objective:To study the effects of Traditional Chinese Medicine Jianpi Chushi decoction and ointment on chronic ***:DNCB acetone solution was used to sensitize the skin of back and ears of 36 rats in order to establish chronic eczema model.A total of 36 rats were divided into four groups of 9 randomly including oral medicine group,external inunctum group,combination therapy group,and model control group ***,the blank group of 4 healthy rats were *** oral medicine group was given Traditional Chinese Medicine Jianpi Chushi decoction [(Poria cocos,Chinese yam,Cortex dictamni,Zaocys dhumnade,Rhizoma atractylodis,Pericarpium citri reticulatae,Scutellaria baicalensis,Radix Sophorae Flavescentis,Raw Radix Paeoniae Alba,Licorice roots(Northwest Origin)] by gastric infusion(1.6 g/m L·5 m L/d); the external inunctum group was given qingpeng ointment on the skin,the combination therapy group was given Jianpi Chushi decoction by gastric infusion and qingpeng ointment combination *** model control group was given normal saline(NS) of the same volume by gastric infusion and vaseline on *** administration 15 d and stopped for 3 *** thickness difference and weight difference of left and right ear of every group were measured and the degree of ear swelling were *** CD4^+ and CD8^+ content and the IL-2,IL-4 level of serum were detected,and the inflammatory cells counts of back skin were ***:After treatment,the degree of ear swelling of oral medicine group,external inunctum group and combination therapy group significant decreased compared with model control group(P<0.05).The CD4^+,CD8^+ cell content and IL-2 level of oral medicine group,external inunctum group,combination therapy group and model control group significant decreased compared with blank group,and IL-2 level and the inflammatory cells count *** 15 d of treatment,the CD4^+,CD8^+ cell content and IL-2 level of serum of oral medicine gro

关键词： Chronic eczema Rat Jianpi Chushi decoction qingpeng ointment Combination therapy

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