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Biochemical recurrence of pathological T2+localized prostate cancer after robotic-assisted radical prostatectomy:A 10-year surveillance

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World Journal of Clinical Cases 2021年第5期9卷 1026-1036页

作者： Che Hseuh Yang Yi Sheng Lin Yen Chuan Ou Wei Chun Weng Li Hua Huang Chin Heng Lu Chao Yu Hsu Min Che Tung Division of Urology Department of SurgeryTungs'Taichung MetroHarbor HospitalTaichung 435403Taiwan

BACKGROUND pT2+prostate cancer(PCa),a term first used in 2004,refers to organ-confined PCa characterized by a positive surgical margin(PSM)without extracapsular *** with a PSM are vulnerable to biochemical recurrence(BCR)following radical prostatectomy(RP);however,whether adjuvant radiotherapy(aRT)is imperative to PSM after RP remains *** study had the longest follow-up on pT2+PCa after robotic-assisted RP since ***,we discussed our viewpoints on pT2+PCa based on real-world *** To conclude a 10-year surveillance on pT2+PCa and compare our results with those of the published *** Forty-eight patients who underwent robotic-assisted RP between 2008 and 2011 were *** serial tests of prostate specific antigen(PSA)≥0.2 ng/mL were defined as *** designed factors were analyzed using statistical tools for BCR *** 9.4 was applied and significance was defined as Pspecificity:0.739).The linear regression analysis showed no correlation between time to BCR and preoperative PSA(Pearson’s correlation,0.13;adjusted R2=0.026).CONCLUSION Robotic-assisted RP in pT2+PCa of worse conditions can provide better BCR-free survival.A surgical technique limiting the PSM in favorable situations is warranted to lower the pT2+PCa BCR *** PSA cut-off value of 19.09 ng/mL is a predictive factor for *** on our experiences and review of the literat

关键词： prostatectomy/methods Robotic surgical procedures Prostatic neoplasms/pathology prostate-specific antigen/metabolism Margins of excision Retrospective study

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