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prospects of borehole NMR instruments and applications Dedicated to Professor Chaohui Ye on the occasion of his 80th birthday

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Magnetic Resonance Letters 2022年第4期2卷 224-232页

作者： Sihui Luo Jiangfeng Guo Lizhi Xiao College of Artificial Intelligence and College of Petroleum Engineering China University of PetroleumBeijing102249China State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing102249China

Borehole nuclear magnetic resonance(NMR)is a powerful technology to characterize the petrophysical properties of underground reservoirs in the petroleum industry.The rising complexity of oil and gas exploration and development objectives,as well as the novel application contexts of underground reservoirs,have led to increasingly demanding requirements on borehole NMR technology including instrument design and related processing methods.This mini review summarizes the advances and applications of borehole NMR instruments along with some future possibilities.It may be helpful for researchers and engineers in the petroleum industry to understand the development status and future trends of borehole NMR technology.

关键词： Borehole Nuclear magnetic resonance(NMR) Instrument Oil and gas exploration and development prospects

High entropy materials based electrocatalysts for water splitting:Synthesis strategies,catalytic mechanisms,and prospects

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Nano Research 2023年第4期16卷 4411-4437页

作者： Xiumin Li Yifan Zhou Changrui Feng Ran Wei Xiaogang Hao Keyong Tang Guoqing Guan School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China Graduate School of Sustainable Community Studies Hirosaki University1-BunkyochoHirosaki 036-8560Japan Graduate School of Science and Technology Hirosaki University3-BunkyochoHirosaki 036-8561Japan Department of Chemical Engineering Taiyuan University of TechnologyTaiyuan 030024China Energy Conversion Engineering Laboratory Institute of Regional InnovationHirosaki University3-BunkyochoHirosaki 036-8561Japan

Among various electrocatalysts,high entropy materials(HEMs)have attracted great attention due to the distinctive designing concept and unique properties with captivating electrocatalytic activity and stability.To date,HEMs have been a new family of advanced electrocatalysts in the research field of water electrolysis.In this work,the structural features and synthesis strategies of high entropy catalysts are reviewed,especially,their performances for catalyzing hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)in water electrolysis are presented,in which the crucial roles of structure,composition,multisites synergy,and“four core effects”for enhancing catalytic activity,stability,and resistance of electrochemical corrosion are introduced.Besides,the design tactics,main challenges,and future prospects of HEM-based electrocatalysts for HER and OER are discussed.It is expected to provide valuable information for the development of low-cost efficient HEM-based electrocatalysts in the field of water electrolysis.

关键词： water electrolysis high entropy electrocatalysts synthesis strategies catalytic mechanisms prospects

Microneedles for Enhanced Topical Treatment of Skin Disorders:Applications,Challenges,and prospects

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Engineering 2023年第11期30卷 170-189页

作者： Tingting Peng Yangyan Chen Wanshan Hu Yao Huang Minmin Zhang Chao Lu Xin Pan Chuanbin Wu International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development Ministry of Education of the People’s Republic of ChinaCollege of PharmacyJinan UniversityGuangzhou 511436China School of Pharmaceutical Sciences Sun Yat-sen UniversityGuangzhou 510006China Faculty of Pharmacy University of HelsinkiHelsinki 00014Finland

Microneedles(MNs)can be used for the topical treatment of skin disorders as they directly deliver therapeutics to the site of skin lesions,resulting in increased therapeutic efficacy while having minimum side effects.MNs are used to deliver different kinds of therapeutics(e.g.,small molecules,macromolecules,nanomedicines,living cells,bacteria,and exosomes)for treating various skin disorders,including superficial tumors,wounds,skin infections,inflammatory skin diseases,and abnormal skin appearance.The therapeutic efficacy of MNs can be improved by integrating the advantages of multiple therapeutics to perform combination therapy.Through careful designing,MNs can be further modified with biomimetic structures for the responsive drug release from internal and external stimuli and to enhance the transdermal delivery efficiency for robust therapeutic outcomes.Some studies have proposed the use of drug-free MNs as a promising mechanotherapeutic strategy to promote wound healing,scar removal,and hair regeneration via a mechanical communication pathway.Although MNs have several advantages,the practical application of MNs suffers from problems related to industrial manufacture and clinical evaluation,making it difficult for clinical translation.In this study,we summarized the various applications,emerging challenges,and developmental prospects of MNs in skin disorders to provide information on ways to advance clinical translation.

关键词： Microneedles Transdermal drug delivery system Skin disorders Treatments Challenges prospects

Phosphatidylserine:An overview on functionality,processing techniques,patents,and prospects

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Grain & Oil Science and Technology 2023年第4期6卷 206-218页

作者： Jingnan Chen Jun Li Haoyu Xu Jiaxi Li Yonghong Yuan Xuebing Xu Yanlan Bi College of Food Science and Engineering Henan University of TechnologyZhengzhou 450001China Wilmar(Shanghai)Biotechnology Research and Development Center Co. Ltd.Shanghai 200137China Enzymecode Biotechnology Co. Ltd.Binhai New DistrictTianjin 300457China

Phosphatidylserine(PS)is the part of cell structure in the body and has many beneficial functions especially in brain-related aging diseases.Although daily foods can provide PS to human body,the amount is very limited due to its poverty in most foods.To overcome the issue,numerous studies based on PS have been reported to develop PS-related supplements.In this review,PS was comprehensively and critically reviewed from the view of resources,functions,processing techniques,patents,and prospects.For resources,animal,plant,and microorganism origins were all covered with their differences in composition profiles.For functions,benefits regarding memory,cognitive enhancement,exercise performance,reducing Alzheimer’s disease,and attention-deficit hyperactivity disorder symptoms were covered as well as the functional differences among animal-,plant-,and microorganism-based PS-related supplements.For processing techniques,traditional extracting methods from animal,plant,and microorganism tissues were comparatively discussed with enzymatic synthesis based on different reaction systems.Finally,patents of PS-related supplements were evaluated as well as their applications.This review could provide scientific and valuable support for PS industry.

关键词： Phosphatidylserine Functionality Processing techniques Patents evaluation prospects

prospects of immunotherapy for cancer

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Frontiers of Medicine 2019年第1期13卷 1-2页

作者： Zhinan Chen National Translational Science Center for Molecular Medicine Xi'an 710032China Department of Cell Biology School of Basic MedicineFourth Militaiy Medical UniversityXi'an 710032China

Cancer is a significant global health problem and remains one of the most challenging threats to human health. Conventional cancer treatments may include surgery, chemotherapy, radiation therapy, targeted therapy, and immunotherapy. Immunotherapy is still considered as a highly exciting field for new discoveries and treatments for cancer [1]. Immunotherapy was cited by Science as one of the top 10 breakthroughs in the world in 2013.

关键词： prospects immunotherapy cancer

Galectin-3 prospects as a therapeutic agent for multiple sclerosis

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Neural Regeneration Research 2019年第8期14卷 1380-1382页

作者： Laura Thomas Laura Andrea Pasquini Department of Biological Chemistry School of Pharmacy and Biochemistry Institute of Chemistry Biological Physicochemistry (IQUIFIB) University of Buenos Aires and National Research Council (CONICET)

Galectin-3 (Gal-3) in oligodendrocyte (OLG) differentiation: OLGs are the cells in charge of myelination in the central nervous system (CNS), allowing rapid conduction of the neural action potential and giving trophic support to axons. OLGs undergo a series of changes throughout their life cycle: first, upon neural stem cell comm让ment to the OLG lineage, cells referred to as OLG precursor cells (OPC) present a bipolar morphology, have proliferative and migratory capacity and express molecular markers like platelet-derived growth factor receptor alpha and neural/glial antigen 2.

关键词： multiple sclerosis therapeutic agent Galectin-3 prospects

Review of and prospects for China＇s human and economic geography

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Journal of Geographical Sciences 2017年第12期27卷 1556-1576页

作者： CHEN Mingxing LONG Hualou WANG Chengjin HUANG Jinchuan NIU Fangqu Institute of Geographic Sciences and Natural Resources Research CASBeijing 100101China Key Laboratory of Regional Sustainable Development Modeling CASBeijing 100101China

The ＂High-Level Forum of the Development of China＇s Human Geography Under the Background of Change＂ was held in Beijing on January 22-23, 2016. More than 30 pro-fessors attended this forum. At this conference, they discussed the major progress made towards developing China＇s human geography, as well as the existing problems, limiting fac- tors, opportunities, international collaborations, emerging directions, and prospects in the development of this discipline. In recent years human geography has boomed, generating many important opportunities for its development. Establishing an academic community for joint research on major research issues and collaborative innovation is a promising and im- portant route to take. We should embrace both domestic and international characteristics, to promote China＇s human geography onto the world stage. Meanwhile, the cultivation of vari- ous scholarly talents is also of great value to enrich and advance the discipline.

关键词： human and economic geography research review prospects High-Level Forum

Status and prospects of nutritional cooking

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Food Quality and Safety 2019年第3期3卷 137-143页

作者： Wang Yong Li Amin Chen Dongpo Hangzhou Robam Appliances CO. LTD.HangzhouZhejiang311100China

With the rapid development of national economic level,people’s living standards have been greatly improved,leading to people’s higher attention to their daily diet.However,there are still a great number of people who have not realized the importance of healthy diet,which could result in many health problems such as under-nutrition or over-nutrition.The cooking process has a significant impact on food nutrition,thus a fast,convenient and healthy new cooking process has a great potential to be developed and applied in our daily life.

关键词： cooking nutrition status prospects

Research advances of Galliformes since 1990 and future prospects

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Avian Research 2018年第3期9卷 175-187页

作者： Shan Tian Jiliang Xu Jianqiang Li Zhengwang Zhang Yong Wang School of Nature Reserve Beijing Forestry University Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering College of Life Sciences Beijing Normal University Department of Biological and Environmental Science College of Agricultural Life and Natural Sciences Alabama A&M University College of International Education Nanjing Forestry University

Background: Galliformes are widely distributed throughout the world and economically important to humans as domesticated animals or gamebirds. They are at a unique position for advancing knowledge and techniques of wildlife conservation as the barometer of the status of applied ecology. Populations of many galliform species have declined mainly due to habitat loss and over-hunting. An assessment of knowledge of Galliformes could help to provide guidelines for future research and conservation strategies.Methods: Using the Web of Science search engine, we conducted a literature review of galliform-related articles published from 1990 to 2016. We used the "research area" option to filter articles focused on the zoology, environmental sciences ecology, biodiversity conservation, forestry, behavioral sciences, reproductive biology, biochemistry and molecular biology, cell biology, genetics and heredity, evolutionary biology, physiology and developmental biology. We then checked duplication based on the title, abstract and full text. In addition, we examined the reference lists of selected studies to include the publications that were missed by above searching.Results: We retained 1874 articles related to the Galliformes from the initial 243,128 publications that were found. About 91.4% focused on one or two species, and 85.0% were conducted within a short duration, typically 1–2 years. The majority of the articles concentrated on macroscopic ecology(55.5%), mainly focusing on habitat selection or habitat use. With recent advances of molecular biology, the studies of taxonomy and phylogenetics rose quickly in last two decades. The study of physiology and biochemistry was no longer limited to simple description but expanded to the mechanisms of phenotype and micro-evolutionary potential. An additional area receiving increasing attention is the conservation of Galliformes, with the assessment of the conservation status and conservation management effectiveness of Galliformes(e.g. species diversity and genetic diversity)

关键词： Galliformes Web of Science Research advances Future prospects