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Correlation of neutrophil-to-lymphocyte ratio with prolonged icu stayin infants undergoing cardiac surgery

South China Journal of Cardiology 2024年第2期25卷 67-75页

作者：李思敏廖秋凤刘琦 Department of Cardiothoracic Intensive Care Unit Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou 510080GuangdongChina Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences) Southern Medical UniversityGuangzhou 510080GuangdongChina

Background The neutrophil-to-lymphocyte ratio(NLR)stands as a valuable marker for assessing inflammation and predicting adverse outcomes post-cardiac *** study aimed to ascertain the prognostic relevance of preoperative NLR concerning prolonged icu stay among infants undergoing congenital heart surgery employing cardiopulmonary *** A retrospective review was conducted involving 187 consecutive infants(≤1 year)who underwent congenital heart disease surgery between January and April 2019,stratified into two groups based on NLR(NLRprolonged intensive care unit(icu)length of stay,defined patients with icu stays duration higher than the third *** between preoperative NLR and clinical outcomes were *** operating characteristic curve analysis,multivariable Logistic regression,and restricted cube plots were utilized to gauge the association of preoperative NLR with prolonged icu *** The area under the receiver operating characteristic curve of NLRpredictive capability for prolonged icu length of staywas *** analyses revealed poorer prognoses among patients with high NLR(≥0.484).Multivariable Logistic regression analysis indicated that heightened preoperative NLR(OR:2.63,95%CI:1.18-5.83,P=0.018)independently was correlated with prolonged icu length of stay in infants'post-cardiac *** In summary,the NLR emerges as a significant predictive factor for prolonged icu stay in infants undergoing cardiac ***,further research is warranted to comprehensively grasp the relationship between the NLR and prolonged icu stay.

关键词： Congenital heart disease Infants Neutrophil-to-lymphocyte ratio Cardiopulmonary bypass Intensive care unit Cardiac surgery prolonged icu stay

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