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A simple and successful treatment for rupture and defect of the posterior third superior sagittal sinus caused by open depressed skull fracture:A case report

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Chinese Journal of Traumatology 2022年第2期25卷 115-117页

作者： Geng-Huan Wang He-Ping Shen Zheng-Min Chu Jian-Guo Shen Jian Shen Department of Neurosurgery The Second Affiliated Hospital of Jiaxing UniversityJiaxing314000Zhejiang ProvinceChina

It is extremely dangerous to treat the posterior third of the superior sagittal sinus (PTSSS) surgically, since it is usually not completely ligated. In this report, the authors described the case of a 27-year-old man with a ruptured and defective PTSSS caused by an open depressed skull fracture, which was treated by ligation of the PTSSS and the patient achieved a positive recovery. The patient's occiput was hit by a height-limiting rod and was in a mild coma. A CT scan showed an open depressed skull fracture overlying the PTSSS and a diffuse brain swelling. He underwent emergency surgery. When the skull fragments were removed, a 4 cm segment of the superior sagittal sinus (SSS) and the adjacent dura mater were removed together with bone fragments. Haemorrhage occurred and blood pressure dropped. We completed the operation by ligating the severed ends of the fractured sagittal sinus. One month after the operation, apart from visual field defects, he recovered well. In our opinion, in primary hospitals, when patients with severely injured PTSSS cannot sustain a long-time and complicated operation, e.g., the bypass using venous graft, and face life-threatening conditions, ligation of the PTSSS is another option, which may unexpectedly achieve good results.

关键词： Depressed skull fracture Superior sagittal sinus Ligation prognoses

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A Centralized Report on Pediatric Japanese Encephalitis Cases from Beijing Children's Hospital,2013

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Biomedical and Environmental Sciences 2016年第12期29卷 902-908页

作者： LI Jiu Wei GAO Xiao Yan WU Yun FU Shi Hong TAN Xiao Juan CAO Yu Xi ZHANG Wei Hua YIN Zun Dongs HE Ying LI Yi Xing LIANG Guo Dong XU Wen Bo FANG Fang WANG Huan Yu Neurology Department Beijing Children's Hospital Affiliated to Capital Medical UniversityBeijing 100045China Department of Viral Encephalitis National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China State Key Laboratory for Infectious Disease Prevention and Control(SKLID) Chinese Center for Disease Control and PreventionBeijing 202206China Department of Polio National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China National Immunization Programme Chinese Center for Disease Control and PreventionBeijing 100050China

Fifteen pediatric cases of suspected Japanese encephalitis （JE） were reported in Beijing Children＇s Hospital during the late summer of 2013. The clinical manifestations in most cases included high fever, seizures, and abnormal magnetic resonance imaging findings. Twelve of 15 cases were laboratory-confirmed as JE cases by pathogen identification. Epidemiological investigations showed that five of the 12 laboratory-confirmed patients had an incomplete JE vaccination history. Follow-up investigations after discharge indicated that seven laboratory-confirmed JE patients without JE vaccinations had relatively poor prognoses, with an average Modified Rankin Scale （MRS） score of 2.6 when compared with the other five laboratory-confirmed, JE-vaccinated patients with an average MRS score of 0.5. The observation of pediatric JE cases among those with a history of JE vaccination warrants further attention.

关键词： Japanese encephalitis Pediatric prognoses

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Metastatic Prostate Cancer under Androgen Deprivation Therapy: Factors Influencing Castration Resistance

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Open Journal of Urology 2020年第7期10卷 225-232页

作者： Modou Ndiaye Ousmane Sow Babacar Sine Omar Gaye Alioune Sarr Abdoulaye Ndiath Cyrille Ze Ondo Amath Thiam Ndeye Aissatou Bagayogo Samba Thiapato Faye Ndiaga Seck Ndour Aboubacar Traore Ngor Mack Thiam El Hadj Malick Diaw Yaya Sow Boubacar Fall Babacar Diao Alain Khassim Ndoye Urology-Andrology Department Aristide Le Dantec Hospital Dakar Senegal Urology-Andrology Department De la Paix Hospital Ziguinchor Senegal

Objective: To evaluate the factors predicting the time to progression to castration-resistant in metastatic prostate cancer under Androgen Deprivation Therapy (ADT) in our center. Patients and Methods: This is a retrospective, descriptive, analytical study in a single center over a period of 2 years. It has interest patients followed for metastasized prostate cancer under ADT. The parameters studied were: epidemiological, clinical, paraclinical, prostate specific antigen (PSA) nadir, time to nadir (TTN) and their link with the castration resistance. Results: The frequency of castration resistant prostate cancer was 28 patients per year. The mean age was 70.4 ± 7.9 years. An ECOG score ≥ 3 was more common as was the cT2c stage. The median of the initial total PSA was 489.6 ng/ml (203.3;1653.2). All patients had adenocarcinoma. The International Society of Urological Pathology (ISUP) 1 was more frequent. Bone metastases were more frequent. The medians of nadir, TTN and the castration resistance were 19.3 ng/ml (3.7;102.1), 5.5 months (3;9) and 11 months (6;15.3), respectively. The Eastern Cooperative Oncology Group (ECOG) score, clinical stage, metastatic site, the nadir and its TTN influenced the DSR. Age, lymph node involvement, initial total PSA and Gleason score did not influence the castration resistance. Conclusion: ADT should be initiated as soon as possible before an attack of general and/or clinical stage advanced to delay resistance. A drilling should be associated with this hormone therapy as much as possible because of its gain on resistance.

关键词： Cancer Prostate Androgen Deprivation Therapy Resistance prognoses

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