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Absence of enhancement in a lesion does not preclude primary central nervous system t-cell lymphoma:A case report

World Journal of Clinical Cases 2024年第2期12卷 374-382页

作者： Chan-Seop Kim Chi-Hoon Choi Kyung Sik Yi Yook Kim Jisun Lee Chang Gok Woo Young Hun Jeon Department of Radiology Chungbuk National University HospitalChungbuk National University College of MedicineCheongju-si 28644Chungcheongbuk-doSouth Korea Department of Pathology Chungbuk National University HospitalChungbuk National University College of MedicineCheongju-si 28644Chungcheongbuk-doSouth Korea Department of Radiology Seoul National University HosptialSeoul 03080South Korea

BACKGROUND primary central nervous system lymphoma(PCNSL)is a non-Hodgkin lymphoma that originates in the central nervous system(CNS)and is exclusively limited to the *** most PCNSLs are diffuse large B-cell lymphomas,primary CNS t-cell lymphomas(PCNStLs)are *** typically demonstrate some degree of enhancement on contrast-enhanced magnetic resonance imaging(MRI).to the best of our knowledge,non-enhancing PCNStL has not been reported *** SUMMARY A 69-year-old male presented to the neurology department with complaints of mild cognitive impairment and gradual onset of left lower leg weakness over a span of two *** MRI showed asymmetric t2-hyperintense lesions within the *** enhancement was observed on the contrast-enhanced t1 *** initial diagnosis was neuro-Behçet’s *** high-dose steroid therapy,no alterations in the lesions were identified on initial *** patient’s symptoms deteriorated *** MRI performed one month after the initial scan revealed an increased lesion ***,brain biopsy confirmed the diagnosis of *** patient underwent definitive combined ***,the patient developed bacteremia and died of septic shock approximately three months after *** the absence of enhancement in the lesion did not rule out PCNStL.A biopsy approach is advisable for pathological confirmation.

关键词： central nervous system neoplasms Non-Hodgkin lymphoma t-cell lymphoma primary central nervous system lymphoma primary central nervous system t-cell lymphoma Case report

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