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Association between Self-reported Snoring and Prediabetes among Adults Aged 40 Years and Older without Diabetes

Chinese Medical Journal 2017年第7期130卷 791-797页

作者： Hai-Bin Wang Wen-Hua Yan Jing-Tao Dou Zhao-Hui Lu Bao-An Wang Yi-Ming Mu Department of Endocrinology Chinese People's Liberation Army General Hospital Beijing 100853 China

Background：Several previous studies have shown that snoring is associated with glucose metabolism and the development of diabetes,but rare study has shown the association between snoring frequency and prediabetes,particularly in *** hypothesized that individuals who snore might have a higher risk of *** study aimed to investigate the association between self-reported snoring and prediabetes in a Chinese ***：A cross-sectional study was performed in three large communities of Beijing from December 2011 to August 2012 by recruiting individuals aged ≥40 years *** participants were requested to complete a detailed questionnaire and undergo anthropometric measurements.A 75 g oral glucose tolerance test was performed in individuals without *** samples of all participants were collected;blood glucose and blood fat levels were *** logistic regression models were built to assess the association between snoring frequency and ***：A total of 13,592 participants （female：66.56%;mean age：56.8 ＆#177; 7.9 years;mean body mass index：25.5 ± 3.4 kg/m2） were included in the final *** these,30.9% were diagnosed with prediabetes,while 41.3% and 25.4% had occasional and habitual snoring,*** snoring was associated with an increased risk of prediabetes （odds ratio [OR]：1.3,95% confidence interval [CI]：1.1-1.4,P 〈 0.001）,after adjusting for diabetes and sleep-related confounders in the multivariable *** snoring was also associated with isolated impaired fasting glucose （IFG;OR：1.3,95% CI：1.0-1.6;P 〈 0.001） and isolated impaired glucose tolerance （IGT;OR：1.3,95% CI：1.2-1.5;P 〈 0.001）,but not IFG ＋ IGT （OR：1.1,95% CI：0.9-1.4;P =0.281）.When stratified by total cholesterol （TC） levels,this association between habitual snoring and prediabetes was observed only in individuals with TC 〈5.6 mmol/L （OR：1.4,95% CI：1.2-1.6;P〈 0.001）.Conclusions：Habitual snoring is associated with predia

关键词： Cholesterol Community Cross-sectional Studies prediabetic state Snoring

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Observation of the efficacy and safety of the Song-Relaxing and Zhen-Vibrating abdomen manipulation for patients with prediabetes

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Journal of Acupuncture and Tuina Science 2022年第1期20卷 58-64页

作者： LI Min PENG Na ZENG Jiaofei ZHOU Ying DENG Yihui HE Qinghu KONG Xiehe Hunan University of Chinese Medicine Changsha 410208China Hunan Traditional Chinese Medical College Zhuzhou 412012China Hunan Want Want Hospital Changsha 410016China 不详

Objective:To observe the safety of the Song-Relaxing and Zhen-Vibrating abdomen manipulation in treating patients with prediabetes and its effects on blood glucose and lipid ***:One hundred and two patients with prediabetes were divided into a manipulation group and a control group according to the random number table method,with 51 cases in each *** patients received the general behavioral intervention for prediabetes,with additional Song-Relaxing and Zhen-Vibrating abdomen manipulation in the manipulation group and oral metformin hydrochloride tablets in the control *** groups received the intervention for six ***:Fourteen patients dropped out during the treatment,and a total of 88 patients completed the trial,including 45 cases in the manipulation group and 43 cases in the control *** the treatment,the prediabetes control rate was 93.3%in the manipulation group and 74.4%in the control group,and the difference between the two groups was statistically significant(P<0.05);no patient in the manipulation group progressed to diabetes,while the rate of conversion to diabetes in the control group was 6.9%,with a significant difference between the two groups(P<0.05).After the treatment,the body mass index(BMI),glycosylated hemoglobin A1c(HbA1c),fasting plasma glucose(FPG),2-hour postload plasma glucose(2hPG)level during an oral glucose tolerance test(OGTT),fasting insulin(FINS),homeostasis model assessment-2 of insulin resistance(HOMA2-IR),total cholesterol(TC),and triglycerides(TG)decreased in both groups versus baseline,with significant differences within the groups;the levels of all indicators were lower in the manipulation group than in the control group(P<0.05),and the differences between the two groups were more prominent at the sixth month(P<0.01).At the sixth month,the high-density lipoprotein cholesterol(HDL-C)in the manipulation group was increased,while there was no significant change in the control *** the co

关键词： Tuina Massage Manual Therapies Zhen-Vibrating Manipulation prediabetic state Blood Glucose Lipid Metabolism Insulin Resistance

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Evaluation of glucose metabolic disorder: insulin resistance and insulin receptors in critically ill children

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中华医学杂志(英文版) 1996年第10期109卷 809-809页

作者： F Xu X Yang Z Lu F Kuang Pediatric Intensive Care Unit Children's Hospital Chongqing University of Medical Sciences.

OBJECTIVE To explore the pathogenesis of glucose metabolic disorder and insulin resistance in critically ill children under severe *** To test glucose, lactate, glucagon, insulin, c-peptide, cortisol levels in 50 critically ill children. While we measured125I-insulin binding to erythrocytes of 13 critically ill children who had hyperglycemia and hyperinsulinemia. Glucose and lactate were measured biochemically. Insulin, c-peptide, cortisol and glucagon were determined by RIA. Erythrocytes insulin receptor was detected by insulin radioreceptor *** Glucose, lactate, insulin, c-peptide, glucagon, cortisol, insulin/glucose, insulin/glucagon ratio in patients were higher than those in normal controls (P0.05).CONCLUSIONS Hyperglycemia is common in critically ill children during stress, which may be attributed to hormones disturbance and tissure insulin resistance. Insulin receptor defect due to comprehensive factors was one of the important causes for insulin resistance. The blood glucose level can be used as an predicting index in ICU.

关键词： Insulin Resistance Insulins Critical Illness prediabetic state Glucose Metabolism Disorders Child blood glucose levels Intensive Care Units Hyperglycemia C-Peptide insulin binding Insulin Glucose Lactates

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