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Research on the pragmatic clinical trial Design Based on Real-World Study

Asian Journal of Social Pharmacy 2021年第3期16卷 242-249页

作者： Li Gan Zhang Yu Yuan Xiaoliang Chen Yuwen School of Business Administration Shenyang Pharmaceutical UniversityShenyang 110016China Research Institute of Drug Regulatory Science Shenyang Pharmaceutical UniversityShenyang 110016China

Objective To introduce the concept and plan design of pragmatic clinical trials based on real-world study(RWS)so as to provide both guidance for clinical trials and reference for relevant personnel studying *** A retrospective study was made on the design of real-world clinical trials at home and abroad in recent years to summarize their design process and *** and Conclusion The advantages of combining randomization and real-world data in clinical trials are important methods for evaluating medical interventions in the real clinical *** clinical trials can evaluate the therapeutic effects of interventions in real or close to real medical environments to obtain the best real-world evidence.

关键词： RWS pragmatic clinical trial design

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Application of evidence-based medicine methods in integrative oncology research

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Journal of Traditional Chinese Medical Sciences 2023年第2期10卷 129-132页

作者： Jianping Liu Sijia Zhu Nicola Robinson Centre for Evidence-Based Chinese Medicine Beijing University of Chinese MedicineBeijing100029China School of Health and Social Care London South Bank UniversityLondonSE10AAUnited Kingdom

To present the advances of evidence-based medicine and clinical research methodology in integrative oncology,we conducted a literature review of real-world studies of traditional Chinese medicine(TCM)in cancer care and summarized the available *** randomized controlled trials(pRCTs)and clinical registry studies are becoming more popular as they could compensate for the limitations of *** RCTs of TCM for cancer treatment as well as systematic reviews have been *** most investigated therapies are based on acupuncture,Chinese herbal compounds,and Chinese patent *** has a significant advantage in relieving cancer-related *** studies focus more on improving clinical symptoms and laboratory ***,the patient's quality of life deserves more attention.

关键词： Evidence-based medicine Integrative oncology Traditional Chinese medicine Research design pragmatic clinical trial Registries

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