检索结果-南通市图书馆

Formulation and evaluation of herbal gel of pothos scandens Linn

Asian Pacific Journal of Tropical Medicine 2010年第12期3卷 988-992页

作者： Mohammed Haneefa KP Shahima Hanan K Saraswathi R Guru Prasad Mohanta Chandini Nayar Alshifa College of Pharmacy Poonthavanam PostKeralaIndia Department of Pharmacy Annamalai UniversityTamil NaduIndia School of Chemical & Biotechnology SASTRA UniversityTamil NaduIndia

Objective:To formulate pothos scandens Linn(***) leaf extract in to a gel and investigate their burn wound healing ***:Ethanolic extract of dried leaves of P. scandens were subjected to priliminery phytochemical evaluation and wound healing activities *** gel formulations of ethanolic extract of ***(4%w/v) were prepared using polymers carbopol 934 and carbopol 940 bv varying their *** formulations were evaluated for physical parameters,drug ***,viscosity,***. primary skin irritation,pharmacological activity and ***:Wound healing studies of ethanolic extract revealed that *** treated animals were found to epithelise in 22 days while the solvent control and the untreated rats epithelise within 35 and 40 days respectively. The formulation with 1.5%w/w carbopol 934 was found to be more promising as it shows better physicochemical characteristics,higher pharmacological activity and stability compared to other ***:*** alcoholic extract shows significant improvement in burn wound contraction and hence this is a promising candidate in burn wound healing.

关键词： pothos scandens Burn wound healing Herbal gel Carbopol 934 Carbopol 940

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Antioxidant and antipyretic studies on pothos scandens L

引用

Asian Pacific Journal of Tropical Medicine 2011年第11期4卷 889-899页

作者： Thankarajan Sajeesh Karuppusamy Arunachalam Tangaraj Parimelazhagan Department of Botany Bharuthiar UniversityCoimbatore-641 046Tamil NaduIndia

Objective:To investigate pothos scandens for the in vitro antioxidant and antipyretic activity. Methods:Preliminary phylochemicals,total phenolics and flavonoid contents were analyzed in leaf,stem and root *** vitro antioxidant activity was evaluated by different assays such as 2,2-diphenyl-1-picrylhydrazyl（DPPH） radical scavenging,2,2’-azinobis -3-ethylbenzolhiazoline-6-sulphonic acid（ABTS+） radical scavenging,ferric-reducing antioxidant power（FRAP） assay,phosphomolybdenum reduction assay,metal chelating activity, superoxide anion radical scavenging activity,hydrogen peroxide and nitric oxide scavenging *** antipyretic activity of root methanol extract was studied by pyrexia induced by brewer’s yeast on Wistar albino rats at concentration of 200 and 400 mg/kg using paracetamol as standard ***:The total phenolics and tannin content were found to be higher in elhanol extract of stem,whereas total flavonoid content was higher in acetone extract of *** methanol extract of root showed highest free radical scavenging activity in assays namely ABTS assay（8 221.5μM TE/g extract）,FRAP assay[514.4 mM Fe（Ⅱ）/g extract],hydrogen peroxide （60.3%） and nitric oxide scavenging assays（58.7%）.The DPPH assay and superoxide radical assay results revealed that the ethanol extract of root has remarkable free radical scavenging capacity(IC50 0.284 mg/mL and 70.84%).The antipyretic studies on methanol extract of root showed significant reduction of temperature in pyrexia induced rats at 200 and 400 mg/kg doses. Conclusions:These findings justify that pothos scan/km can be a valuable natural antioxidant and antipyretic source which seemed to provide potential nutraccuticals for human health.

关键词： Free radicals Antioxidants Phenolics Flavonoids Pyrexia pothos scandens

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：