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Induced pluripotent stem cells:origins, applications, and future perspectives

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第12期14卷 1059-1069页

作者： Jing ZHAO Wen-jie JIANG Chen SUN Cong-zhe HOU Xiao-mei YANG Jian-gang GAO School of Life Sciences Shandong University

Embryonic stem(ES)cells are widely used for different purposes,including gene targeting,cell therapy,tissue repair,organ regeneration,and so ***,studies and applications of ES cells are hindered by ethical issues regarding cell *** circumvent ethical disputes,great efforts have been taken to generate ES cell-like cells,which are not derived from the inner cell mass of blastocyst-stage *** 2006,Yamanaka et *** reprogrammed mouse embryonic fibroblasts into ES cell-like cells called induced pluripotent stem(iPS)*** one year later,Yamanaka et *** Thomson et *** reprogrammed human somatic cells into iPS *** the first generation of iPS cells,they have now been derived from quite a few different kinds of cell *** particular,the use of peripheral blood facilitates research on iPS cells because of safety,easy availability,and plenty of cell *** iPS cells have been used for cell therapy,disease modeling,and drug *** this review,we describe the generations,applications,potential issues,and future perspectives of iPS cells.

关键词： Induced pluripotent stem cells Origin Peripheral blood cells Application potential issues

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Statistical Analysis of Network Based issues and Their Impact on Social Computing Practices in Pakistan

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Journal of Computer and Communications 2016年第13期4卷 23-39页

作者： Zahoor Hussain Zulﬁqar Ali Bhutto Gulab Rai Majid Hussain Kashif Zaheer Institute of Information and Communication Technology University of Sindh Jamshoro Pakistan Education & Literacy Department Government of Sindh Karachi Pakistan Bahria University Karachi Campus Pakistan Department of Computer Science Karachi University Karachi Pakistan

Social computing and online groups have accompanied in a new age of the network, where information, networking and communication technologies are enabling systematized human efforts in primarily innovative ways. The social network communities working on various social network domains face different hurdles, including various new research studies and challenges in social computing. The researcher should try to expand the scope and establish new ideas and methods even from other disciplines to address the various challenges. This idea has diverse academic association, social links and technical characteristics. Thus it offers an ultimate opportunity for researchers to find out the issues in social computing and provide innovative solutions for conveying the information between social online groups on network computing. In this research paper we investigate the different issues in social media like users’ privacy and security, network reliabilities, and desire data availability on these social media, users’ awareness about the social networks and problems faced by academic domains. A huge number of users operated the social networks for retrieving and disseminating their real time and offline information to various places. The information may be transmitted on local networks or may be on global networks. The main concerns of users on social media are secure and fast communication channels. Facebook and YouTube both claimed for efficient security mechanism and fast communication channels for multimedia data. In this research a survey has been conducted in the most populated cities where a large number of Facebook and YouTube users have been found. During the survey several regular users indicate the certain potential issues continuously occurred on these social web sites interfaces, for example unwanted advertisement, fake IDS, uncensored videos and unknown friend request which cause the poor speed of channel communication, poor uploading and downloading data speed, cha

关键词： Computer Networks Categories of Social Computing Application Facebook and YouTube potential issues Statistical Analysis

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