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Association between operative position and postoperative nausea and vomiting in patients undergoing laparoscopic sleeve gastrectomy

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2088-2095页

作者： Zhao-Peng Li Yan-Cheng Song Ya-Li Li Dong Guo Dong Chen Yu Li Department of Gastrointestinal Surgery The Affiliated Hospital of Qingdao UniversityQingdao 266033Shandong ProvinceChina Department of Operation Room The Affiliated Hospital of Qingdao UniversityQingdao 266033Shandong ProvinceChina

BACKGROUND Bariatric surgery is one of the most effective ways to treat morbid obesity,and postoperative nausea and vomiting(PONV)is one of the common complications after bariatric *** present,the mechanism of the high incidence of PONV after weight-loss surgery has not been clearly explained,and this study aims to investigate the effect of surgical position on PONV in patients undergoing bariatric *** To explore the effect of the operative position during bariatric surgery on *** Data from obese patients,who underwent laparoscopic sleeve gastrectomy(LSG)in the authors’hospital between June 2020 and February 2022 were divided into 2 groups and retrospectively *** logistic regression analysis and the t-test were used to study the influence of operative position on *** There were 15 cases of PONV in the supine split-leg group(incidence rate,50%)and 11 in the supine group(incidence rate,36.7%)(P=0.297).The mean operative duration in the supine split-leg group was 168.23±46.24 minutes and 140.60±32.256 minutes in the supine group(P<0.05).Multivariate analysis revealed that operative position was not an independent risk factor for PONV(odds ratio=1.192,95%confidence interval:0.376-3.778,P=0.766).CONCLUSION Operative position during LSG may affect PONV;however,the difference in the incidence of PONV was not statistically *** position should be carefully considered for obese patients before surgery.

关键词： postoperative nausea and vomiting Bariatric surgery Laparoscopic sleeve gastrectomy Operative positions Obesity

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Intraoperative systemic vascular resistance is associated with postoperative nausea and vomiting after laparoscopic hysterectomy

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World Journal of Clinical Cases 2020年第20期8卷 4816-4825页

作者： Meng-Di Qu Meng-Yuan Zhang Gong-Ming Wang Zhun Wang Xu Wang Department of Anesthesiology Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021Shandong ProvinceChina

BACKGROUND The incidence of postoperative nausea and vomiting(PONV)in patients undergoing laparoscopic hysterectomy is very high compared with other surgeries,even when many prophylactic measures have been ***,the pathogenesis of PONV is *** sex,a history of motion sickness or PONV,nonsmokers,and perioperative opioid use are the most closely related *** the multiple risk factors,suboptimal gastrointestinal(GI)perfusion may be attributed to some cases of PONV,and increased systemic vascular resistance(SVR)may lead to GI *** hypothesis of this research was that SVR is related to *** To investigate the relationship between SVR and PONV in patients undergoing laparoscopic *** A total of 228 patients who underwent elective laparoscopic hysterectomy were included in this prospective observational *** was monitored using a noninvasive hemodynamic monitoring *** indices of SVR,the baseline,mean,area under the curve(AUC),and weighted AUC,were used for *** incidence and severity of nausea and vomiting were evaluated while patients were awake and throughout the intervals from 0 to 2 h,2 to 6 h,and 6 to 24 h starting upon arrival at the post-anesthesia care *** associations between various SVR indices and PONV were investigated by logistic regression.P<0.05 was considered statistically *** The incidence of PONV in the study was 56.14%(128/228),and PONV tended to appear within 6 h after *** variables were significant in univariate analyses,however,only SVR mean[odds ratio(OR)=1.015,95%CI:1.005-1.109,P=0.047]and duration of surgery(OR=1.316,95%CI:1.003-2.030,P=0.012)were associated with PONV after logistic regression ***,patients with high SVR mean were more likely to suffer from PONV after laparoscopic *** average,patients who developed PONV needed more time to tolerate diet and demonstrated poorer sleep quality on the first night

关键词： postoperative nausea and vomiting Systemic vascular resistance Gastrointestinal perfusion Laparoscopic hysterectomy Prospective observational study Pneumoperitoneum

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Effect of anesthesia induction with butorphanol on postoperative nausea and vomiting:A randomized controlled trial

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World Journal of Clinical Cases 2023年第32期11卷 7806-7813页

作者： Fang Xie De-Feng Sun Lin Yang Zhong-Liang Sun Department of Anesthesiology The First Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina Department of Neuroelectrophysiology The First Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina

BACKGROUND postoperative nausea and vomiting(PONV)are common complications that affect the recovery and well-being of elderly patients undergoing gastrointestinal laparoscopic *** To investigate the effect of butorphanol on PONV in this patient *** A total of 110 elderly patients(≥65 years old)who underwent gastrointestinal laparoscopic surgery were randomly assigned to receive butorphanol(40μg/kg)or sufentanil(0.3μg/kg)during anesthesia induction in a 1:1 *** measured outcomes included the incidence of PONV at 48 h after surgery,intraoperative dose of propofol and remifentanil,Bruggrmann Comfort Scale score in the postanesthesia care unit(PACU),number of compressions for postoperative patientcontrolled intravenous analgesia(PCIA),and time to first flatulence after *** The results revealed a noteworthy reduction in the occurrence of PONV at 24 h after surgery in the butorphanol group,when compared to the sufentanil group(T1:23.64%vs 5.45%,T2:43.64%vs 20.00%,Ppostoperative 48-h total infusion volume and hemodynamic parameters,intraoperative dose of propofol and remifentanil,number of postoperative PCIA compressions,time until the first occurrence of postoperative flatulence,and incidence of PONV at 48 h post-surgery(all,P>0.05).Furthermore,patients in the butorphanol group were more comfortable,when compared to patients in the sufentanil group in the *** The present study revealed that butorphanol can be an efficacious substitute for sufentanil during anesthesia induction to diminish PONV within 24 h following gastrointestinal laparoscopic surgery in the elderly,simultaneously improving patient comfort in the PACU.

关键词： Butorphanol Sufentanil Enhanced recovery after surgery Anesthesiology Gastrointestinal surgery postoperative nausea and vomiting

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The selection rules of acupoints and meridians of traditional acupuncture for postoperative nausea and vomiting:a data mining-based literature study

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Traditional Medicine Research 2020年第4期5卷 272-281,I0001,I0002页

作者： Li-Sha Liu Jian Huo Xiu-Li Yuan Yi Lan Jing-Yuan Zhang Hong-Mei Zhong Yu Wang Yun-Sheng He Mianyang Affiliated Hospital Chengdu University of Traditional Chinese MedicineMianyang621000China Chengdu Women's and Children's Central Hospital School of MedicineUniversity of Electronic Science and Technology of ChinaChengdu611731China Sichuan Second Traditional Chinese Medicine Hospital Chengdu610031China

Background:postoperative nausea and vomiting(PONV)refers to a problem commonly occurring after *** is considered a critical complementary alternative therapy for *** acupoints selection critically determines the efficacy of acupuncture,whereas the selection rules remain *** objective of the present study was to delve into the principles of acupoints selection for PONV using data mining ***:The clinical trials assessing the acupuncture effect for PONV were searched with the use of computer in PubMed,China National Knowledge Infrastructure,and Chinese Biomedical Database;the time span was confined as 2009–*** database of acupuncture prescriptions for PONV was built using Excel 2016;the description and association were analyzed by IBM SPSS modeler ***:Eighty-three relevant literatures were screened *** number of specific acupoints took up 72.5%of all acupoints;specific acupoints exhibited the frequency taking up 91.30%of the total *** revealed from the result,Neiguan(PC 6),Zusanli(ST 36),Hegu(LI 4),and Zhongwan(CV 12)were most frequently applied,suggesting the tightest *** acupoints were taken from the stomach meridian and pericardium *** common acupoints were concentrated in the lower limbs,chest,as well as ***:Data mining acts as a feasible method to identify acupoints selection and compatibility *** suggested from our study,the acupoints selection for PONV prioritizes specific acupoints and related *** selection and combination of acupoints comply with the theory of traditional Chinese medicine.

关键词： postoperative nausea and vomiting Acupuncture Data mining Regularity Clinical research

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Comparative study on effects of dexmedetomidine and dexamethasone on the incidence of postoperative nausea and vomiting in patients undergoing laparoscopic surgery

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Journal of Acute Disease 2022年第2期11卷 59-64页

作者： Manpreet Singh Awadh Bihari Tiwari Priya Taank Shalendra Singh Amrinder Kaur Munish Sood Rahul Yadav Department of Anaesthesiology&Critical Care Air Force HospitalKanpur 208004India Department of Ophthalmology Command Hospital(SC)Pune 411040India Department of Anaesthesiology&Critical Care Armed forces Medical CollegePune 411040India Department of Periodontics 304 Field HospitalKanpur 208004India Department of Orthopaedics Indian Naval Hospital Ship AsviniMumbai 400005India Department of Anaesthesiology&Critical Care Indian Naval Hospital Ship AsviniMumbai 400005India

Objective:To compare the safety and efficacy of dexmedetomidine and dexamethasone for the prevention of postoperative nausea and vomiting(PONV)in patients scheduled for laparoscopic ***:A total of 86 female patients were prospectively administered dexmedetomidine 1μg/kg i.v.(the group A,n=43),and dexamethasone 8 mg i.v.(the group B,n=43).The two groups were compared in treatment response,hemodynamic changes,and Numerical Analog Scale(NAS).Besides,the relation of PONV with patient baseline characteristics in the perioperative period was determined as ***:Patients in group A had lower PONV scores(t=3.1,Ppostoperative analgesia.

关键词： Dexmedetomidine postoperative nausea and vomiting Dexamethasone Laparoscopic surgery Anti-emetic

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Palonosetron versus Ondansetron as Prophylaxis against postoperative nausea and vomiting (PONV) after Laparoscopic Sleeve Gastrectomy: A Randomized Controlled Trial

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Open Journal of Anesthesiology 2020年第10期10卷 349-360页

作者： Ayman A. Elrashidy Mohamed Elsherif Wahiba Elhag Omar Abdelaziem Sherif Abdelaziem Reda Sobhi Abdel-Rahman Anesthesia Department Faculty of Medicine Tanta University Tanta Egypt Bariatric and Metabolic Surgery Department Hamad Medical Corporation Doha Qatar Faculty of Medicine Qatar University Doha Qatar Surgery Department Faculty of Medicine Tanta University Tanta Egypt Surgery Department Hamad Medical Corporation Doha Qatar

Introduction: postoperative nausea and vomiting (PONV) are prevalent symptoms after laparoscopic surgeries with an incidence rate of (54% - 79%) in bariatric procedures. Despite its popularity, limited studies assesse... 详细信息

Introduction: Postoperative nausea and vomiting (PONV) are prevalent symptoms after laparoscopic surgeries with an incidence rate of (54% - 79%) in bariatric procedures. Despite its popularity, limited studies assessed the effect of antiemetics for PONV prophylaxis after laparoscopic sleeve gastrectomy (LSG). The aim of this trail is to compare the effectiveness of a single pre-induction intravenous dose of Palonosetron versus Ondansetron for prophylaxis of PONV, 24 hours after LSG. Subjects and Methods: This prospective randomized controlled double-blind parallel-group study was conducted from May till December 2019. Recruited patients were consented and randomized using a closed envelop method into two groups with fifty patients each. The total number of nausea and vomiting attacks in the 24 hours postoperatively was considered as a primary end point. The secondary end points were the frequency of nausea, retching and vomiting attacks in the 24 hours post-surgery. The severity of nausea was evaluated using a 10 cm visual analogue scale (VAS). Results: This RCT incl

关键词： Palonosetron Ondansetron postoperative nausea and vomiting PONV Retching Laparoscopic Sleeve Gastrectomy LSG Bariatric Surgery

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Electroacupuncture on PC6 Prevents Opioid-Induced nausea and vomiting after Laparoscopic Surgery

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Chinese Journal of Integrative Medicine 2013年第4期19卷 277-281页

作者： Siwoo Lee Myeong Soo Lee Deok Hwa Choi Su Kyung Lee Korea Institute of Oriental Medicine University of Science and Technology DaejeonSouth Korea Department of Anesthesiology Wonkwang University School of MedicineIksanSouth Korea Department of Oriental Rehabilitation Medicine Wonkwang University School of Oriental MedicineIksanSouth Korea

Objective： To investigate the treatment time dependence of electroacupuncture （EA） on Neiguan （PC6） for preventing postoperative nausea and vomiting （PONV）. Methods： One hundred and seventy-eight patients, who had received intravenous patient-controlled analgesia （PCA） with Fentanyl, were assigned randomly to three groups using random numbers： a pre-operative EA group （PrEA）, a post-operative EA group （PoEA）, and a non-acupuncture control group （NC）. An anesthetist evaluated the incidence and severity of nausea and vomiting for 48 h after surgery blindly. The main outcomes were severity and freguency of PONV, which were measured with a self-reported questionnaire and a confirmation from the anesthetist. The data were analyzed with ANOVA and Z-test. Results： The incidence of nausea and vomiting was significantly lower in the PrEA group than the NC group during 48 h after surgery （P〈0.01, P〈0.05）. The incidence of vomiting was also significantly lower in the PrEA group than the PoEA group （P〈0.05）. The PoEA subjects evidenced no significant differences compared with the NC subjects in terms of the incidence of nausea and vomiting （P〈0.05）. The severity of nausea was significantly lower in the PrEA group than in the NC and PoEA groups （P〈0.05）. Conclusions： EA on PC6 is effective in the prevention of PONV, and pre-operative acupuncture is more effective than post-operative acupuncture.

关键词： electroacupuncture Neiguan (PC6) postoperative nausea and vomiting

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Evaluation of Transcutaneous Electroacupoint Stimulation with the Train-of-four Mode for Preventing nausea and vomiting after Laparoscopic Cholecystectomy

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Chinese Journal of Integrative Medicine 2008年第2期14卷 94-97页

作者：刘育勇段善娥蔡明雪邹鹏来勇李雅兰 Department of Anesthesia the First Affiliated Hospital Jinan University

Objective： To evaluate the efficacy of transcutaneous electroacupoint stimulation with a train-of-four （TOF） mode for the prevention of postoperative nausea and vomiting （PONV） in the patients undergoing laparoscopic cholecystectomy. Methods： Ninety-six ASA Grade Ⅰ-Ⅱ patients scheduled for laparoscopic cholecystectomy were randomized into Neiguan （P6） electroacupoint stimulation group （treated group） and a placebo control group （placement of electrodes without electroacupoint stimulation）. The anesthetic regimen was standardized by needling at Neiguan on the left side and connecting the TOF peripheral nerve stimulator. The incidence of nausea, vomiting, severity, antiemetic dosage and the degree of pain were assessed at 0, 60, 120 min, and 24 h after surgery. Results： The incidence of nausea and vomiting, the dose of antiemetics and the occurrence of severe nausea were all significantly lower in the treated group compared with the control group and the score for pain was obviously reduced in patients of the treated group at 24 h post-operation （P〈0.05 or P〈0.01）. Conclusion： Transcutaneous electroacupoint stimulation at P6 with the TOF mode could reduce the incidence and severity of nausea and vomiting with analgesic effects.

关键词： transcutaneous acupoint electrical stimulation train-of-four stimulation postoperative nausea and vomiting laparoscopic cholecystectomy

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Optimizing surgical outcomes for elderly gallstone patients with a high body mass index using enhanced recovery after surgery protocol

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World Journal of Gastrointestinal Surgery 2023年第10期15卷 2191-2200页

作者： Yue-Xia Gu Xin-Yu Wang Yang Chen Jun-Xiu Shao Shen-Xian Ni Xiu-Mei Zhang Si-Yu Shao Yu Zhang Wen-Jing Hu Ying-Ying Ma Meng-Yao Liu Hua Yu Department of Nursing Shanghai Fourth People’s Hospital Affiliated to Tongji University School of MedicineShanghai 200434China Department of General Surgery Shanghai Fourth People’s Hospital School of Medicine Tongji UniversityShanghai 200434China Department of Nursing Shanghai Xuhui Central HospitalShanghai 200031China

BACKGROUND Rehabilitation of elderly patients with a high body mass index(BMI)after cholecystectomy carries risks and requires the adoption of effective perioperative management *** enhanced recovery after surgery(ERAS)protocol is a comprehensive treatment approach that facilitates early patient recovery and reduces postoperative *** To compare the effectiveness of traditional perioperative management methods with the ERAS protocol in elderly patients with gallbladder stones and a high *** This retrospective cohort study examined data from 198 elderly patients with a high BMI who underwent cholecystectomy at the Shanghai Fourth People's Hospital from August 2019 to August *** them,99 patients were managed using the traditional perioperative care approach(non-ERAS protocol),while the remaining 99 patients were managed using the ERAS *** indicator data were collected for patients preoperatively,intraoperatively,and postoperatively,and surgical outcomes were compared between the two *** The comparison results between the two groups of patients in terms of age,sex,BMI,underlying diseases,surgical type,and preoperative hospital stay showed no statistically significant ***,the ERAS group had a significantly shorter preoperative fasting time than the non-ERAS group(4.0±0.9 h vs 7.6±0.9 h).Regarding intraoperative indicators,there were no significant differences between the two groups of ***,in terms of postoperative recovery,the ERAS protocol group exhibited significant advantages over the non-ERAS group,including a shorter hospital stay,lower postoperative pain scores and postoperative hunger scores,and higher satisfaction *** readmission rate was lower in the ERAS protocol group than in the non-ERAS group(3.0%vs 8.1%),although the difference was not ***,there were significant differences between the two groups in terms of postoperative nausea and vomit

关键词： Enhanced recovery after surgery protocol Cholecystectomy Rehospitalization rate postoperative nausea and vomiting Degree of abdominal distension Daily living ability

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Effect of acupoint sticking at Shenque （CV 8） for preventing spleen-stomach disharmony caused by venous analgesia pump

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Journal of Acupuncture and Tuina Science 2018年第3期16卷 167-170页

作者： Ye Fu-ying Yu Ya-ping Huang Wen-hong The First Affiliated Hospital of Zhejiang Chinese Medical University Hangzhou 310005China

Objective： To observe the clinical effect of acupoint sticking of Chinese medicine at Shenque （CV 8） for preventing spleenstomach disharmony caused by venous analgesia pump. Methods： A total of 120 post-surgery patients using venous analgesia pump and also conforming to the inclusion criteria were randomized into 2 groups by the random number table. There were 58 patients in the control group who received conventional post-surgery nursing care, and there were 62 patients in the treatment group who received acupoint sticking at Shenque （CV 8） on the basis of conventional nursing care. After treatment, the incidences of postoperative nausea and vomiting, and abdominal bloating were measured. Results： The total incidence of nausea, vomiting and abdominal bloating in the treatment group was 11.3%, versus 39.7% in the control group, and the difference of the incidence between the two groups showed a statistical significance （P〈0.05）. In comparison of the severity of spleen-stomach dishormony which happened during 72 h after surgery, cases in the treatment group showed lower severity than those in the control group （P〈0.05）. Conclusion： Acupoint sticking at Shenque （CV 8） can effectively prevent spleen-stomach disharmony caused by venous analgesia pump, which will alleviate sufferings of the patients.

关键词： Point Shenque (CV 8) Acupoint Sticking Therapy Analgesics Pain postoperative Spleen-stomach Disharmony postoperative nausea and vomiting Drug-related Side Effects and Adverse Reactions

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