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Electroencephalogram findings in 10 patients with post-stroke epilepsy:A retrospective study

World Journal of Clinical Cases 2024年第2期12卷 249-255页

作者： Li-Min Wen Ran Li Yan-Ling Wang Qing-Xia Kong Min Xia Clinical Medicine College Jining Medical UniversityJining 272067Shandong ProvinceChina School of Basic Medical Sciences Shandong UniversityJinan 250012Shandong ProvinceChina Department of Neurology The Affiliated Hospital of Jining Medical UniversityJining 272007Shandong ProvinceChina

BACKGROUND post-stroke epilepsy is a common and easily overlooked complication of acute cerebrovascular ***-term seizures can seriously affect the prognosis and quality of life of ***(EEG)is the simplest way to diagnose epilepsy,and plays an important role in predicting seizures and guiding *** To explore the EEG characteristics of patients with post-stroke epilepsy and improve the detection rate of inter-seizure epileptiform *** From January 2017 to June 2020,10 patients with post-stroke epilepsy in our hospital were *** clinical,imaging,and EEG characteristics were *** stroke location,seizure type,and ictal and interictal EEG manifestations of the patients with post-stroke epilepsy were then retrospectively *** In all 10 patients,epileptiform waves occurred in the side opposite to the stroke lesion during the interictal stage;these manifested as sharp wave,sharp-wave complex,or spike discharges in the anterior head lead of the side opposite to the *** In EEG,epileptiform waves can occur in the side opposite to the stroke lesion in patients with post-stroke epilepsy.

关键词： post-stroke epilepsy Electroencephalogram Seizure stroke Slow wave

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Blood and CSF biomarkers for post-stroke epilepsy:a systematic review

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Acta Epileptologica 2022年第3期5卷 127-135页

作者： Priya Dev Mareena Cyriac Kamalesh Chakravarty Abhishek Pathak Department of Neurology Institute of Medical ScienceBanaras Hindu UniversityVaranasi 221005India Department of Neurology PGIMERChandigarh 160012India

post-stroke epilepsy is a common complication of ischemic stroke which adversely affects the prognosis of *** and radiological parameters cannot adequately predict the ***,the discovery of biomarkers is imperatively needed for predicting post-stroke *** conducted a systematic review of diagnostic and prognostic biomarkers for post-stroke epilepsy through a comprehensive literature search in different *** articles that met our inclusion criteria were assessed for quality using the modified Quality Assessment of Diagnostic Accuracy Studies *** eligible studies were included in this systematic *** of 22 assessed biomarkers,nine biomarkers showed significant association with post-stroke *** T allele of CD40(cluster of differentiation 40)−1C/T polymorphism,the CC genotype of TRPM6(transient receptor potential cation channel subfamily M member 6)rs2274924,the allele polymorphism of MAD2(mitochondrial aldehyde dehydrogenase 2),the mRNA level of interleukin-6(IL-6),the plasma level of endostatin,and the mRNA expression of IL-1βshow a positive correlation with post-stroke epilepsy;while S100 calcium-binding protein B,heat shock 70 kDa protein-8 and neuropeptide Y are inversely associated with post-stroke *** a small number of patients were recruited,further studies are needed to confirm their potential use for predicting post-stroke epilepsy.

关键词： post-stroke epilepsy Biomarker stroke Blood and CSF biomarker Systematic review

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