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portal Fibrotic Cord is Associated with Transjugular Intrahepatic Portosystemic Shunt Failure and Death in Cirrhotic Patients

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Journal of Clinical and Translational Hepatology 2023年第4期11卷 809-816页

作者： Yunshu Yang Chuangye He Xulong Yuan Kai Li Wenyuan Jia Jing Niu Na Han Jiao Xu Ying Zhu Li Xu Yuxuan Mao Yuanping Xu Xiaoyuan Gou Jun Tie National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases Air Force Medical UniversityXi’anShaanxiChina

Background and Aims:Occlusive portal vein thrombosis(PVT)often causes portal hypertension-related complications in cirrhotic *** intrahepatic portosystemic shunt(TIPS)is an effective treatment for this difficult ***,the factors influencing TIPS success and overall survival in patients with occlusive PVT are *** study investigated the factors influencing TIPS success and overall survival in cirrhotic patients with occlusive ***:Cirrhotic patients with occlusive PVT were selected from a prospective database of consecutive patients treated with TIPS in Xijing Hospital between January 2015 and May *** characteristics,TIPS success rate,complications,and survival were collected,and the factors associated with the TIPS success rate and transplant-free survival were ***:A total of 155 cirrhotic patients with occlusive PVT were *** succeeded in 126(81.29%)*** 1-year survival rate was 74%.Compared with those without,patients with portal fibrotic cord had a lower TIPS success rate(39.02%vs.96.49%,prelated complications(12.20%vs.1.75%,pportal fibrotic cord(odds ratio 0.024)was a risk factor for TIPS *** and multivariate analysis showed that portal fibrotic cord was an independent predictor of death(hazard ratio 2.111;95%CI:1.094-4.071,p=0.026).Conclusions:portal fibrotic cord increased the TIPS failure rate and is a risk factor for poor prognosis in cirrhotic patients.

关键词： Fibrotic cord Occlusive portal vein thrombosis portal hypertension-related complications Transjugular intrahepatic portosystemic shunt Liver cirrhosis

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