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portal ductopathy:Clinical importance and nomenclature

World Journal of Gastroenterology 2011年第11期17卷 1410-1415页

作者： Yusuf Bayraktar Department of Internal Medicine Gastroenterology ClinicHacettepe University HospitalsAnkara 06100Turkey

Non-cirrhotic portal hypertension(PHT)accounts for about 20%of all PHT cases,portal vein thrombosis(PVT) resulting in cavernous transformation being the most common *** known complications of PHT may be encountered in patients with chronic ***,the effect of this entity on the biliary tree and pancreatic duct has not yet been fully ***,a dispute remains regarding the nomenclature of common bile duct abnormalities which occur as a result of chronic *** many clinical reports have focused on biliary abnormalities,only a few have evaluated both the biliary and pancreatic ductal *** this review the relevant literature evaluating the effect of PVT on both ductal systems is discussed,and findings are considered with reference to results of a prominent center in Turkey,from which the term"portal ductopathy"has been put forth to replace"portal biliopathy".

关键词： portal hypertension portal vein thrombosis portal vein cavernous transformation Congenital hepatic fibrosis Non-cirrhotic portal hypertension portal ductopathy portal double ductopathy portal biliopathy

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How can portal vein cavernous transformation cause chronic incomplete biliary obstruction?

引用

World Journal of Gastroenterology 2012年第26期18卷 3375-3378页

作者： Ozgur Harmanci Yusuf Bayraktar Department of Medicine Division of GastroenterologyFaculty of MedicineHacettepe University06100 AnkaraTurkey

Biliary disease in the setting of non-cirrhotic portal vein thrombosis(and similarly in portal vein cavernous transformation) can become a serious problem during the evolution of *** is mostly due to portal biliary *** are several mechanisms that play a role in the development of portal biliary ductopathy,such as induction of fibrosis in the biliary tract(due to direct action of dilated peribiliary collaterals and/or recurrent cholangitis),loss of biliary motility,chronic cholestasis(due to fibrosis or choledocholithiasis) and increased formation of cholelithiasis(due to various factors).The management of cholelithiasis in cases with portal vein cavernous transformation merits special *** of a heterogeneous clinical presentation and concomitant pathophysiological changes that take place in biliary anatomy,diagnosis and therapy can become very *** to increased incidence and complications of cholelithiasis,standard treatment modalities like sphincterotomy or balloon sweeping of bile ducts can cause serious ***,biliary strictures and hemobilia are the most common complications that occur during management of these *** this review,we specifically discuss important issues about bile stones related to bile duct obstruction in non-cirrhotic portal vein thrombosis and present evidence in the current literature.

关键词： portal vein cavernous transformation Chole-lithiasis Hemobilia portal ductopathy portal biliopathy

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