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Retrograde embolization technique of the right gastric artery during the implantation of port-catheter system for hepatic arterial infusion chemotherapy

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Journal of Interventional Medicine 2021年第1期4卷 27-31页

作者： Jungang Hu Guang Cao b Liang Xu Kanglian Zheng Xu Zhu Renjie Yang Xiao Wang Xiaodong Wang Department of Radiology Civil Aviation General HospitalBeijing100123China Department of Interventional Radiology Peking University Cancer Hospital&InstituteKey Laboratory of Carcinogenesis and Translational Research(Ministry of Education)Beijing100142China Department of Epidemiology and Biostatistics Peking University Sixth HospitalBeijing100191China

Objective:This study aimed to introduce and evaluate a new embolization technique for the right gastric artery(RGA) during percutaneous implantation of a port-catheter system for hepatic arterial infusion chemotherapy(HAIC).Methods:From January 2013 to January 2017,159 patients with unresectable advanced liver cancer underwent percutaneous implantation of a port-catheter *** 86 of these patients(56 men;aged 28-88 years;mean:60.6±12.0 years),in whom the RGA was obvious on arteriography,embolization of RGA was attempted using microcoils to protect the gastric mucosa during *** the first phase(first three years),antegrade embolization of the RGA using a 2.7 Fr microcatheter was performed in 55 *** the second phase(next two years),embolization of the RGA was attempted by combining antegrade embolization and retrograde embolization through the left gastric artery(LGA) in 31 *** success rates and the incidence of acute gastroduodenal mucosal toxicity(AGMT) in these two groups were ***:The total success rate of the RGA embolization was 70.9%.The success rate was 83.9% in 31 patients who underwent combined antegrade and retrograde embolization,which was significantly higher than that of antegrade embolization alone(63.6%) performed in 55 patients(p=0.047).No complications related to embolization of RGA were *** incidence of AGMT was 29.1%(16/55) in patients in the first phase,which was significantly higher than that in the patients in the second phase(9.7%,3/31)(p=0.037).Conclusion: A combination of retrograde embolization via LGA could increase the success rates of RGA embolization and reduce the incidence of AGMT after HAIC.

关键词： Hepatic arterial infusion chemotherapy Right gastric artery embolization Left gastric artery port-catheter system Acute gastroduodenal mucosal toxicity

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