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Breast-conserving surgery and sentinel lymph node biopsy for breast cancer and their correlation with the expression of polyligand proteoglycan-1

引用

World Journal of Clinical Cases 2022年第10期10卷 3113-3120页

作者： Fu-Ming Li Dan-Ying Xu Qi Xu Yan Yuan Department of Breast Surgery The Second Hospital of JiaxingJiaxing 314000Zhejiang ProvinceChina

BACKGROUND Breast cancer is a malignant tumor with an unclear etiology and is the most common malignant tumor in *** is the main clinical treatment for breast *** traditional total mastectomy combined with axillary lymph node dissection is effective,it can result in shoulder dysfunction,especially in middle-aged and elderly patients with breast cancer with weak constitution and other underlying ***,the postoperative quality of life is *** To assess breast-conserving surgery and sentinel lymph node biopsy for breast cancer treatment and their correlation with polyligand *** Overall,80 patients with breast cancer treated in our hospital from January 2021 to July 2021 were retrospectively selected and divided into an observation group(n=44)and control group(n=36)according to the treatment *** observation group was treated with breast-conserving surgery and sentinel lymph node biopsy,and the control group was treated with total breast ***,immunohistochemical staining was used to detect the expression of syndecan-1(SDC-1)in the lesions,and its relationship with clinicopathological findings was *** Intraoperative blood loss,operation time,and hospital stay in the observation group were 65.51±9.94 m L,65.59±9.40 min,and 14.80±3.03 d,respectively,which were significantly lower than those in the control group(P11.36%,which was significantly lower than that in the control group(P1 in the observation group was 25.00%,and there was no significant difference between the groups(P>0.05).The positive expression rate of SDC-1 in patients with American Joint Committee on Cancer(AJCC)stageⅡwas 14.29%,which was significantly lower than that in patients with AJCC stageⅠ(P1 had no significant relationship with age,course of dise

关键词： Breast preservation Sentinel lymph node biopsy Breast cancer Clinical effectiveness polyligand proteoglycan-1

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