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Monitoring of Respiratory Infections in the Intensive Area of Respiratory System Disease

Advances in Microbiology 2014年第9期4卷 560-566页

作者： Filippo Ricciardiello Maria Cardone Giuseppe Fiorentino Massimo Mesolella Flavia Oliva Annalisa Pianese Carlo Antonio Leone UOC of Otorhinolaryngology “Federico II” University Naples Italy UOC of Otorhinolaryngology “Monaldi” Hospital Naples Italy UOC Respiratory Diseases Physiopathology and Rehabilitation Second University of Naples “Monaldi” Hospital Naples Italy UOC Subintensive Respiratory Therapy Unit “Monaldi” Hospital Naples Italy

Respiratory infections are the most frequent nosocomial infections after those urinaries and surgicals. We analysed respiratory infection incidences in patients treated with different kinds of respiratory assistance (non-invasive ventilation and invasive mechanical ventilation trough tracheostomy), studying 640 patients recovering in the intensive area of respiratory disease from 2010 to 2013. We had 113 cases of respiratory infections: 42.5% in patients of non-invasive ventilation group and 57.5% of patients treated with invasive ventilation with a statistically significant difference between the two groups. The patients treated with non-invasive ventilation showed a lower incidence of nosocomial respiratory infections. Prevention guidelines are important to reduce nosocomial infections frequency.

关键词： Intensive Respiratory Area Multi-Resistant Pathogens Nosocomial Infections pneumonias Tracheostomy

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Evaluation of Association between <i>Chlamydophila pneumoniae</i>and Atherosclerotic Plaques in Coronary Artery Disease Patients with Abnormal Angiography

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Health 2014年第18期6卷 2505-2509页

作者： Darioush Iranpour Frahad Abbasi Kamran Mirzayee Nahid Mohammadzadeh Alireza Raeisi Akram Najafi Bushehr University of Medical Science Bushehr Iran The Persian Gulf Tropical Medicine Research Center Bushehr University of Medical Sciences Bushehr Iran The Persian Gulf Marine Biotechnology Research Center Bushehr University of Medical Sciences Bushehr Iran

The role of Chlamydophila pneumoniae in pathogenesis of atherosclerosis is one of the most important discussions in coronary artery diseases. In this study, the relationship between C. pneumoniae seropositivity and atherosclerotic plaque was evaluated among two groups: one group with significant coronary stenosis and one group with normal coronary angiography. Serum C. pneumonia IgM and IgG were evaluated and compared in case and control groups. The seropositivity rates of IgM and IgG antibodies were not statistically differ between case and control groups, although the incidences of positivity were more in case group. The results of our study did not show a correlation between C. pneumonia infection and atherosclerotic plaque or coronary artery stenosis neither in acute nor in chronic infection. More precise studies are needed to clarify the probable inflammatory cascade that starts with C. pneumonia infection and lead to development of atherosclerotic plaque.

关键词： Chlamydophila pneumonias Atherosclerosis Angiography Infection

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