检索结果-南通市图书馆

Value of Preoperative Hematological Parameters in the Prognosis of Gastric Cancer Patients Undergoing a Total Gastrectomy

引用

Current Medical Science 2022年第2期42卷 348-356页

作者： Xi-shan ZHU Ye ZHAO Fei-yan MA Shi-kai WU Oncology Department Peking University First HospitalBeijing100034China Pathology Department Peking University First HospitalBeijing100034China

Objective This study aimed to evaluate the relationships between the albumin/globulin ratio(AGR),neutrophil/lymphocyte ratio(NLR),and Platelet/lymphocyte ratio(PLR)and clinicopathological information for gastric cancer patients.In addition,the prognostic values of these hematological parameters for resectable gastric cancer patients undergoing a total gastrectomy were determined.Methods A total of 245 patients with gastric cancer who underwent a total gastrectomy at our hospital between January 1,2005,and December 30,2015,were enrolled into this study.The preoperative AGR,NLR,and PLR in the serum samples of the patients were measured.The relationships between the hematological parameters and the disease-free survival(DFS)as well as overall survival(OS)were analyzed by statistical analysis.Results The cutoff values of AGR,NLR,and PLR were 1.57,3.5,and 193,respectively.Univariate analyses demonstrated that a low AGR,a high NLR,and a high PLR were significant risk factors for a poor prognosis.According to multivariate analysis,a high PLR was found to be independently associated with a poor survival.Additionally,when age was considered as a stratified factor,univariate analyses demonstrated that a low AGR had the tendency to be correlated with a shorter DFS in nonelderly patients(<65 years old).A low AGR was significantly correlated with a shorter DFS and OS in elderly patients(≥65 years old).Conclusion AGR,NLR,and PLR are independent risk factors associated with a poor gastric cancer survival by univariate analysis,and AGR is an independent risk factor for predicting DFS and OS in elderly patients(≥65 years old)with gastric cancer after total gastrectomy.

关键词： albumin/globulin ratio neutrophil/lymphocyte ratio Platelet/lymphocyte ratio gastric cancer prognosis disease-free survival overall survival cancer microenvironment gastrectomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Association between routine hematological parameters and sudden sensorineural hearing loss:A meta-analysis

引用

Journal of Otology 2021年第1期16卷 47-54页

作者： Wei Ni Shao-Peng Song Yi-Dao Jiang Department of Otolaryngology-Head and Neck Surgery Jingzhou Central HospitalThe Second Clinical Medical CollegeYangtze UniversityJing Zhou434020PR China

Objective:Recent studies have shown that chronic inflammation contributes to the development of sudden sensorineural hearing loss(SSNHL).Some hematologic parameters have also been linked to the prognosis of SSNHL.However,the prognostic value of such hematological factors is not conclusive.This study explored the association of routine hematological parameters with SSNHL.Methods:A systematic literature search was conducted in PubMed,Cochrane Library,Web of Science and Embase to identify eligible studies.Standardized mean deviation(SMD)and the 95%confidence interval(CI)were retried from relevant studies for analysis.Heterogeneity,subgroup,and publication bias analyses were performed.Results:A total of 18 studies involving 1505 SSNHL patients and 1466 healthy persons were enrolled in the final analysis.The study population included 699 responders and 458 non-responders to treatment.Pooled results revealed that the neutrophil/lymphocyte ratio(NLR)and Platelet/lymphocyte ratio(PLR)value in the SSNHL patient group were higher than in the healthy group(SMD=1.05,95%CI:0.86,1.24,pplatelet volumes(MPV)between the groups(SMD=0.03,95%CI:0.44,0.49,p=0.91).Notably,NLR and PLR values were evidently higher in the unrecovered group than in the recovered group(SMD=0.63,95%CI:1.02,0.23,p=0.002,SMD=0.4,95%CI:0.76,0.03,p=0.03,respectively).However,the MPV value was similar in both groups(SMD=0.35,95%CI:1.14,0.44,p=0.38).Conclusions:Our results show that NLR and PLR values can predict the onset and prognosis of SSNHL.

关键词： Sudden sensorineural hearing loss Prognosis Neutrophil/lymphocyte ratio Platelet/lymphocyte ratio Meta-analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：