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A tool for estimating antiretroviral medication coverage for HIV-infected women during pregnancy(PMTCT-ACT)

Global Health Research and Policy 2019年第1期4卷 87-94页

作者： Bruce A.Larson Nafisa Halim Isaac Tsikhutsu Margaret Bii Peter Coakley Peter C.Rockers Department of Global Health Boston University School of Public Health801 Massachusetts AvenueBostonMA 02118USA Kenya Medical Research Institute U.S.Army Medical Research DirectorateAfricaKenya U.S.Military HIV Research Program Walter Reed Army Institute of ResearchSilver SpringMDUSA Henry Jackson Foundation MRI KerichoKenya

Background:In the typical prevention of mother to child transmission(PMTCT)of HIV cascade of care discussion or analysis,the period of analysis begins at the first visit for antenatal care(ANC)for that *** starting point is problematic for two reasons:(1)a large number of HIV-infected women are already on life-long antiretroviral therapy(ART)when presenting for ANC;and(2)women present to ANC at different gestational *** PMTCT ART Coverage Tool(PMTCT-ACT),which estimates the proportion of days covered(PDC)with ART,was developed to address each of these ***:PDC is a preferred method to measure adherence to chronic medications,such as *** evaluating the PMTCT cascade of care,as indicated by PDC with ART over various time periods,a“starting point”based on a specific day before delivery must be defined that applies to all women(treatment experienced or naïve at the first ANC visit at any gestational age).Using the example of 168 days prior to delivery(24 weeks),PMTCT-ACT measures PDC with ART during that ***-ACT is provided as a STATA *** an example dataset for two women(ID1 is treatment experienced;ID2 is treatment naïve),the details of each major portion of the tool(Parts 1-5)are ***-ACT along with the intermediate datasets created during the analysis are provided as supplemental ***:Evaluating the PMTCT cascade of care requires a standard definition of the follow-up period during pregnancy that applies to all HIV-infected pregnant women and a standard measure of ***-ACT is a new tool that fits this ***-ACT can also be easily adjusted to evaluate other ante-and post-natal periods(e.g.,final 4 weeks,final 8 weeks,complete pregnancy period,initial 24 weeks postpartum,time periods consistent with infant HIV testing guidelines).

关键词： HIV Pregnancy Prevention of mother-to-child transmission Cascade of care pill count Coverage Proportion of days covered

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