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Pharmacodynamic evaluation for antiplasmodial activity of Holarrhena antidysentrica(Kutaja) and Azadirachta indica(Neemb) in Plasmodium berghei infected mice model

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Asian Pacific Journal of Tropical Medicine 2013年第7期6卷 520-524页

作者： Jadhav Priyanka Lal Hingorani Kshirsagar Nilima University Department of Infectious Diseases and University Department of Interpathy Research and Technology.Maharashtra University of Health sciences.Mumbai India Pharmanza Herbals Pvt.Ltd. MumbaiIndia Office of National Chair(Clinical Pharmacology).Indian Council of Medical Research(ICMR).Government of India Dean ESI-PGIMSR MGM HospitalGovt.of India.MumbaiIndia

Objective:To investigate in-vivo anti-plasmodial activity of aqueous extracts of plants selected based on the symptomology mentioned in ***:The aqueous extracts of Holarrhena antidysentrica(***)(Kutaja) and Azadirachta indica(***)(Neemb) for their antiplasmodial potential in Plasmodium berghei(***) infected mice was assessed using peters four day suppressive *** the extracts were administered at 2 dose levels,full dose(1 000 mg/d) and minimized dose(200 mg/d).10~6 *** infected RBCs were injected on day ’0’ and treated from day ’0’ till day ’3’ post-infection,Tail blood smears were collected, giemsa stained and *** mice were observed for survival and parasitemia was assessed till 50%of mice in control ***:It was observed that the percentage of parasitemia increased gradually in all the groups,with maximum in control group(Day 3-35,Day 9-46.98) and minimum in Chloroquine arm(Day *** 9-19.92).The percentage of parasitemia was compared using Mann-Whitney U test depicting that all test groups exhibited reduction in parasitemia as compared to control(P-values).These groups showed similar percentage of survival as ***:The present investigation demonstrated the anti-plasmodial effects of *** and *** are two most commonly used medicinal plants in Ayurved for treatment of fever.

关键词： Holarrhena antidysentrica Azadirachta indica Plasmodium berghei Malaria peter’s 4 day test Ayurved Parasitemia

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Ground Magnetic survey for the Investigation of Iron Ore Deposit at Oke-Aro in Iseyin East, south-Western Nigeria

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International Journal of Geosciences 2018年第7期9卷 415-427页

作者： Mufutau Amobi Adebisi Department of Physics University of Ibadan Ibadan Oyo State Nigeria

A ground magnetic survey was carried out to investigate the presence of iron ore at a location (Lat. 7.99883°N to Lat. 7.99933°N, Long. 3.57900°E to Long. 3.57990°E) in Iseyin, Oyo state, south-western Nigeria. Ten magnetic traverses each 100 m long at a separation of 5 m were run West-East. Magnetic intensity was taken at intervals of 10 m along each traverse line using the proton precession magnetometer (G-856 AX). The measured magnetic field data were corrected for drift and were presented as profiles. The profiles were interpreted by calculating the depth to the top of anomalies. The data obtained were used to construct magnetic anomaly maps in 2D and 3D. The magnetic survey results delineated this location into some high and low magnetic field intensity regions. The regions of high magnetic field anomaly indicated the presence of materials with high susceptibility which was suspected to be iron compounds. The quantitative and qualitative analyses on interpretations of field data collected were given, while these results provided values for the total component measurements of ground magnetic anomaly that widely ranged between a maximum positive peak result of 8 nT and to a minimum negative peak result of —6 nT. Using peter’s half slope technique, depth to the basement was assessed, which actually provided a maximum depth to basement of 6.25 m. From the knowledge of the geology of the area and also, the magnetic survey employed information, therefore, we can finally conclude that, the study area is under laid by geologic structures which favour the accumulation of iron-ore minerals deposit at Oke-Aro area in Iseyin.

关键词： Magnetic survey Proton Precession Magnetometer Ground Magnetic Iron-Ore 2-Dimensional 3-Dimensional GPs peter’s Half slope Anoma-lies Iseyin

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