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急性有机磷农药中毒胆碱酯酶水平变化与临床意义

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中华医学写作杂志 2005年第13期12卷 1098-1100页

作者：许桂军浙江省义乌市中心医院急诊科，浙江义乌322000

目的：检测急性有机磷农药中毒(AOPP)患者血清胆碱酯酶(CHE)水平变化井讨论其临床意义。万法：测定138例AOPP患者予中毒入院即刻、第2、3、4、5、6、7天以及120例正常健康人血清CHE水平变化。结果：138例AOPP患者的血清CHE与正常对照比... 详细信息

目的：检测急性有机磷农药中毒(AOPP)患者血清胆碱酯酶(CHE)水平变化井讨论其临床意义。万法：测定138例AOPP患者予中毒入院即刻、第2、3、4、5、6、7天以及120例正常健康人血清CHE水平变化。结果：138例AOPP患者的血清CHE与正常对照比较，轻者中毒第4、5天后差异无统计学意义(P>0．05)，中、重度中毒第7天差异仍有统计学意义(P0．05)，其余各组各时均有统计学意义(P<0．01)。结论：AOPP患者血清CHE下降，但临床中毒程度与血清CHE下降程度不相平行，故血清CHE降低对AOPP的诊断有重要意义，而对判断中毒程度意义不大。

关键词：有机磷农药中毒胆碱酯酶(phosphate pesticide poisoning acetylcholine esterase)

中间期肌无力综合征logistic回归模型的建立

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岭南急诊医学杂志 2009年第5期14卷 356-358页

作者：罗小波梁平华雷明广西医科大学第三附属医院急诊科 530031

目的:尝试建立中间型综合征的logistic回归模型,以便较为客观地预测中间型综合征(IMS)的早期发生。方法:连续观察2000年4月～2009年2月广西医科大学附属三院收治的急性有机磷农药中毒患者136例,按成组设计分为IMS组27例与非IMS组109例... 详细信息

目的:尝试建立中间型综合征的logistic回归模型,以便较为客观地预测中间型综合征(IMS)的早期发生。方法:连续观察2000年4月～2009年2月广西医科大学附属三院收治的急性有机磷农药中毒患者136例,按成组设计分为IMS组27例与非IMS组109例。观察指标为入院24 h内的农药种类,服用剂量,复能剂量,洗胃次数,血糖,血钾,胆碱脂酶(AchE),红细胞,肝功白蛋白,年龄,是否出现烟碱样症状,呼吸骤停,阿托品化及导泻。采用logistic逐步回归方法筛选变量建立回归模型。结果:建立预测模型为:[LnR/(1-R)]=-1.844±2.196烟碱样症状-0.053胆碱酯酶。ROC曲线下面积为0.884;Hosmer-Lemeshow拟合优度检验P值为0.469,表明模型拟合较好。结论:烟碱样症状和AchE作为IMS的两个主要因素建立回归模型后可应用于IMS的早期预测。

关键词：中间期肌无力型综合 logistic回归模型 pesticide Poisoning Logistic Regression Model logistic逐步回归 IMS 急性有机磷农药症状建立预测模型烟碱拟合优度检验曲线下面积主要因素中毒患者早期预测早期发生医科大学模型拟合服用剂量

THE OPERATION METHOD OF ULTRA-LOW-VOLUME SPRAYING WITH AIRPLANE

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Journal of Northeast Forestry University 1996年第1期7卷 48-50页

作者：杜守宪

Techniques and measurements of ultra-low-volume spraving with airplane are studied. From practice it shows tha we can achieve good results of prevention and control of diseases and pests, if we take the following measures: The speed of flying is 160 km/h. The height of flying is 5 to 7m for plain and 15 to 20m for mountain area. The flashing point is over 70℃. The sparying width is 60m. The size of fog drop is 80 to 120μ. The density of fog drop is over 10 drops per cm2.

关键词： Ultra-low-volume Spraying pesticide

Graph attention convolutional neural network model for chemical poisoning of honey bees’ prediction

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Science Bulletin 2020年第14期65卷 1184-1191,M0004页

作者： Fan Wang Jing-Fang Yang Meng-Yao Wang Chen-Yang Jia Xing-Xing Shi Ge-Fei Hao Guang-Fu Yang Key Laboratory of pesticide&Chemical Biology Ministry of EducationCollege of ChemistryCentral China Normal UniversityWuhan 430079China International Joint Research Center for Intelligent Biosensor Technology and Health Central China Normal UniversityWuhan 430079China Collaborative Innovation Center of Chemical Science and Engineering Tianjin 300072China

The impact of pesticides on insect pollinators has caused worldwide concern. Both global bee decline and stopping the use of pesticides may have serious consequences for food security. Automated and accurate prediction of chemical poisoning of honey bees is a challenging task owing to a lack of understanding of chemical toxicity and introspection. Deep learning(DL) shows potential utility for general and highly variable tasks across fields. Here, we developed a new DL model of deep graph attention convolutional neural networks(GACNN) with the combination of undirected graph(UG) and attention convolutional neural networks(ACNN) to accurately classify chemical poisoning of honey bees. We used a training dataset of 720 pesticides and an external validation dataset of 90 pesticides, which is one order of magnitude larger than the previous datasets. We tested its performance in two ways: poisonous versus nonpoisonous and GACNN versus other frequently-used machine learning models. The first case represents the accuracy in identifying bee poisonous chemicals. The second represents performance advantages. The GACNN achieved ~6% higher performance for predicting toxic samples and more stable with ~7%Matthews Correlation Coefficient(MCC) higher compared to all tested models, demonstrating GACNN is capable of accurately classifying chemicals and has considerable potential in practical *** addition, we also summarized and evaluated the mechanisms underlying the response of honey bees to chemical exposure based on the mapping of molecular similarity. Moreover, our cloud platform(http://***) of this model provides low-cost universal access to information, which could vitally enhance environmental risk assessment.

关键词： Deep learning Graph attention convolutional neural networks Honey bees toxicity pesticide Molecular design

Crystal　Structure　of　2－Thio－2－（3＇－methyl－4＇－chloro－oxyphenyl）－1，3，2－benzodioxaphosphole

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Chinese Journal of Structural Chemistry 1995年第6期 75-77页

作者： Sun Ming Liu Xiao-Lan Miao Fang-Ming(Instiitute of Chemical crystallography,Tianjin Mormal University,Tianjin 300074) Li Yu-Gui Wang Jian(Institute of Elemento-Organic Chemistry,Nankai University,300071)

ＣｒｙｓｔａｌＳｔｒｕｃｔｕｒｅｏｆ２－Ｔｈｉｏ－２－（３＇－ｍｅｔｈｙｌ－４＇－ｃｈｌｏｒｏ－ｏｘｙｐｈｅｎｙｌ）－１，３，２－ｂｅｎｚｏｄｉｏｘａｐｈｏｓｐｈｏｌｅＳｕｎＭｉｎｇ；ＬｉｕＸｉａｏ－Ｌａｎ；Ｍｉａｏ... 详细信息

ＣｒｙｓｔａｌＳｔｒｕｃｔｕｒｅｏｆ２－Ｔｈｉｏ－２－（３＇－ｍｅｔｈｙｌ－４＇－ｃｈｌｏｒｏ－ｏｘｙｐｈｅｎｙｌ）－１，３，２－ｂｅｎｚｏｄｉｏｘａｐｈｏｓｐｈｏｌｅＳｕｎＭｉｎｇ；ＬｉｕＸｉａｏ－Ｌａｎ；ＭｉａｏＦａｎｇ－Ｍｉｎｇ（Ｉｎｓｔｉｉｔ...

关键词： molecular structure benzodioxaphosphole X-ray diffraction pesticide

Understanding the Unique Characteristics of Suicide in China: National Psychological Autopsy Study

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Biomedical and Environmental Sciences 2005年第6期18卷 379-389页

作者： GONG-HUAN YANG MICHAEL R. PHILLIPS MAI-GENG ZHOU LI-JUN WANG YAN-PING ZHANG DONG XU （Position at time of study） Chinese Academy of Preventive Medicine Beijing China （Current position） Institute of Basic Medical Sciences Chinese Academy of Medical Science Peking Union Medical College China Beijing Suicide Research and Prevention Center Beijing Hui Long Guan Hospital China Beijing China Chinese Center for Disease Control and Prevention Beijing China

Objective To compare the characteristics of suicides in the four main demographic groups： urban males, urban females, rural males and rural females in order to help clarify the demographic pattern of suicides in China. Methods A detailed psychological autopsy survey instrument was independently administered to 895 suicide victims in family members and close associates from 23 geographically representative locations from around the country. Results pesticide ingestion accounted for 58% （519） of all suicides and 61% （3181519） of deaths were due to unsuccessful medical resuscitation. A substantial proportion （37%） of suicide victims did not have a mental illness. Among the 563 victims with mental illness, only 13% （76/563） received psychiatric treatment. Compared to other demographic groups, young rural females who died from suicide had the highest rate of pesticide ingestion （79%）, the lowest prevalence of mental illness （39%）, and the highest acute stress from precipitating life events just prior to the suicide. Contusion Many suicides in China are impulsive acts of deliberate self-harm following acute interpersonal crises. Prevention of suicides in China must focus on improving awareness of psychological problems, improving mental health services, providing alternative social support networks for managing acute interpersonal conflicts, limiting access to pesticides, and improving the resuscitation skills of primary care providers.

关键词： Suicide China's Mainland Psychological autopsy Case-control studies Community surveys Risk factors Mentaldisorders Depression Suicide tool pesticide Negative life event

Trends in Suicide by Poisoning in China 2000-2006: Age, Gender, Method, and Geography

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Biomedical and Environmental Sciences 2008年第3期21卷 253-256页

作者： XING ZHANG HAI-SHAN LI QIU-HONG ZHU JING ZHOU SHUANG ZHANG LIN ZHANG CHENG-YE SUN National Institute for Occupational Health and Poison Control Chinese Center for Disease Control and Prevention Beijing 100050 China

Objective This study analyzed patterns of suicide and suicide attempts by poisoning as reported through a national poison control system for the purpose of improving intervention and prevention. Methods During the period of 2000 to 2006, 6440 cases of poisoning suicide were reported to the telephone consultation service system of The National Center for Poisoning Control （Chinese Center for Disease Control and Prevention）. Among these records, 4728 cases had completed data for this analysis in terms of age, sex, trend of time and location, and type of poisons. Results There were 60.6% female cases with the age from 10 to 90 years old. The age of cases from 20 to 39 years accounted for 54.5% of all age groups. Both the numbers and percentage in record related to poisoning consultation of oral poisoning suicide showed an increasing tendency during the 7 years. In particular, there was a drastic increase from 2004 to 2006. In addition, the high frequency of cases occurred from May to October. Hebei, Shandong, Henan, and Anhui Provinces had the highest number of cases. pesticide poisonings were the most common method in these cases of consultation for suicide and suicide attempts. Conclusion This study describes epidemiological characteristics in the oral poisoning suicide cases and provides scientific basis for suicide prevention interventions.

关键词： Suicide by poisoning Tendency pesticide Intervene

Comparison of Three Single-Nozzle Operator-Carried Spray Applicators for Whitefly (<i>Bemisia tabaci</i>) Management on Squash

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Agricultural Sciences 2015年第11期6卷 1381-1386页

作者： Alvin M. Simmons Shaaban Abd-Rabou Mohammed Hindy U.S. Vegetable Laboratory United States Department of Agriculture (USDA) Agricultural Research Service Charleston SC USA Whiteflies Unit Scale Insects and Mealybugs Department Egyptian Ministry of Agriculture and Land Reclamation Agricultural Research Center Plant Protection Research Institute Giza Egypt Spray Technology Research Department Egyptian Ministry of Agriculture and Land Reclamation Agricultural Research Center Plant Protection Research Institute Giza Egypt

Whiteflies cause problems in vegetable production on a global scale. The primary worldwide whitefly pest is Bemisia tabaci (Gennadius). Insecticides are commonly used to mitigate the whitefly problem in vegetable crops. In limited-resource crop production, operator-carried spray applicators are commonly used for pesticide treatments. Three single-nozzle operator-carried spray applicators were assessed for their efficacies for whitefly (B. tabaci) control on summer squash (Cucurbita pepo L.) in Egypt. Each knapsack spray equipment was evaluated with five biorational and conventional insecticides. Counts of whitefly nymphs (first, second, third and fourth instars) on leaf samples were taken on 3, 9, 15 and 21 days after treatments with the insecticides. Nymphal mortality varied about 10% among the three spray equipment treatments. The Economy Micro Ulva sprayer resulted in significantly more nymphal mortality as compared with the Arimitsu sprayer and the CZP-3 sprayer, respectively. All insecticides greatly suppressed the whitefly populations;mean mortality ranged from 73% to 95% for all nymphs combined by day for a given treatment. These results provide pest management practitioners with performance assessment of the three operator-carried pesticide applicators for whitefly management with selected foliar insecticides.

关键词： Bemisia tabaci Vegetable Portable pesticide Applicator Pest Management Limited-Resource Producer

Policy, Economy & Finance

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China Chemical Reporter 2009年第8期20卷 18-18页

pesticide Innovations Bank on Biotech The Chinese Academy of Sciences(CAS)on March 2rd released its annual high-techdevelopment report for 2009,which dis-cusses *** trend for modern pesticide innova-tion is towards"green",the report said,re-ferring to products with high efficiency andlow toxic,low dosage and low residue andeasy *** pesticide renovation has been increas-ingly relying on advanced ***-pesticides are regarded as additionalname of advanced pesticides in the post-genomics *** on the biotech,increasing high-ef-ficient and environmental-friendly pesti-cides have been developed and applied inagricultural and forest ***,biotech is not only used in the research

关键词： pesticide friendly biotechnology dosage genomics T