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personal glucose meters coupled with signal amplification technologies for quantitative detection of non-glucose targets:Recent progress and challenges in food safety hazards analysis

引用

Journal of Pharmaceutical Analysis 2023年第3期13卷 223-238页

作者： Feng He Haijie Wang Pengfei Du Tengfei Li Weiting Wang Tianyu Tan Yaobo Liu Yanli Ma Yuanshang Wang A.M.Abd El-Aty Institute of Food&Nutrition Science and Technology Shandong Academy of Agricultural SciencesShandong Provincial Key Laboratory of Agro-Products Processing TechnologyKey Laboratory of Novel Food Resources ProcessingMinistry of AgricultureJinan250100China School of Life Sciences and Food Engineering Hebei University of EngineeringHandanHebei056038China College of Life Sciences Yantai UniversityYantaiShandong264005China College of Food Science and Technology Huazhong Agricultural UniversityWuhan430070China Department of Pharmacology Faculty of Veterinary MedicineCairo University12211GizaEgypt Department of Medical Pharmacology Medical FacultyAtaturk University25240ErzurumTurkey

Ensuring food safety is paramount *** effective detection methods to ensure food safety can be challenging owing to trace hazards,long detection time,and resource-poor sites,in addition to the matrix effects of *** glucose meter(PGM),a classic point-of-care testing device,possesses unique application advantages,demonstrating promise in food ***,many studies have used PGM-based biosensors and signal amplification technologies to achieve sensitive and specific detection of food *** amplification technologies have the potential to greatly improve the analytical performance and integration of PGMs with biosensors,which is crucial for solving the challenges associated with the use of PGMs for food safety *** review introduces the basic detection principle of a PGM-based sensing strategy,which consists of three key factors:target recognition,signal transduction,and signal *** studies of existing PGM-based sensing strategies combined with various signal amplification technologies(nanomaterial-loaded multienzyme labeling,nucleic acid reaction,DNAzyme catalysis,responsive nanomaterial encapsulation,and others)in the field of food safety detection are *** perspectives and potential opportunities and challenges associated with PGMs in the field of food safety are *** the need for complex sample preparation and the lack of standardization in the field,using PGMs in combination with signal amplification technology shows promise as a rapid and cost-effective method for food safety hazard analysis.

关键词： Food safety personal glucose meter Signal amplification Point-of-care testing Detection principle

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