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periorbital Necrotizing Fasciitis Caused by Streptococcus Viridians

Open Journal of Ophthalmology 2015年第2期5卷 74-78页

作者： Belinda Pustina Naser Salihu Department of Ophthalmology University Clinical Center of Kosovo Prishtina Kosovo

Necrotizing fasciitis (NF) is a life threatening soft tissue infection characterized by necrosis of fascia and subcutaneous tissue. If this disease is misdiagnosed and mistreated, because of the fast spreading, it can lead to death. Prompt treatment with antibiotics and surgical debridement is necessary and lifesaving in this disease. In uncomplicated cases and early stages of the disease it can be treated only with intravenous antibiotics. This study presents a 70-year-old female, farmer who approached in our clinic with edema of periorbital region and a minor trauma in her lower eyelid. First skin anthrax of eyelids was considered in differential diagnosis, because the patient was in contact with animals. Culture taken from the wound resulted positive for Streptococcus viridians α hemolytic Streptococcus: the viridians group. Treatment with Ceftriaxone + Penicillin was initiated immediately. Patient responded to intravenous antibiotics and after 2 days the edema began to regress. After 2 weeks patient was discharged from the hospital and the clinical outcome was satisfactory. Based on this case early diagnosed necrotizing fasciitis may be treated only with antibiotics.

关键词： periorbital Necrotizing Fasciitis Streptococcus Viridians Minor Trauma

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The Efficacy and Safety of Succinylated Atelocollagen and Adenosine for the Treatment of periorbital Wrinkles

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Journal of Cosmetics, Dermatological Sciences and Applications 2013年第3期3卷 234-241页

作者： Dong Jin Ryu Jin Young Jung Kee Yang Chung Hwal Suh Sang Ho Oh Ju Hee Lee De- partment of Medical Engineering Yonsei University College of Medicine Seoul Korea Department of Dermatology and Cutaneous Biology Research Institute Yonsei University College of Medicine Seoul Korea

The degradation of structural collagen contributes to the characteristic appearance of wrinkles. The anti-wrinkle effects of a variety of substances have been studied, but the potential anti-wrinkle effects of topical applications of collagen for periorbital wrinkles have not been investigated. To evaluate the effects of topical application of succinylated atelocollagen on periorbital wrinkles and to compare the results of treatment with adenosine, a clinical study on Korean participants was carried out. Each participant’s right or left periorbital area was treated with either a solution containing succinylated atelocollagen and adenosine or a solution containing only succinylated atelocollagen for two months. A placebo solution was applied to the opposite periorbital area of each patient’s face for two months. Based on objective and subjective measurements of clinical improvement, the assessment scores for treated sites were statistically significantly higher than scores for placebo sites after two months of treatment. Analysis of silicone casts of periorbital wrinkles demonstrated partial effects of succinylated atelocollagen on periorbital wrinkles. However, we did not observe any effects of adenosine on periorbital wrinkles. Succinylated atelocollagen may be an effective treatment option for periorbital wrinkles, but further studies including a longer treatment period and larger subject group are needed to verify these results.

关键词： Adenosine Succinylated Atelocollagen periorbital Wrinkles

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Clinical features and prognosis of multiple myeloma and orbital extramedullary disease:Seven cases report and review of literature

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World Journal of Clinical Cases 2022年第33期10卷 12365-12374页

作者： Wan-Li Hu Jia-Yin Song Xin Li Xiao-Jiao Pei Jia-Jia Zhang Man Shen Ran Tang Zhen-Yu Pan Zhong-Xia Huang Department of Hematology Multiple Myeloma Medical Center of BeijingBeijing Chao-Yang HospitalCapital Medical UniversityBeijing 100043China Department of Radiology Beijing Chao-Yang HospitalCapital Medical UniversityBeijing 100043China

BACKGROUND Multiple myeloma(MM)complicated with extramedullary disease(EMD)has a poor prognosis and is a limiting factor in the treatment of MM,and no standard treatment is recommended in international *** studies have reported MM with periorbital *** SUMMARY In this paper,the clinical characteristics and survival of seven patients with multiple myeloma and orbital are described and *** common ocular symptoms were blurred vision,proptosis and/or eye movement disorders,IgG type MM may be a risk factor for orbital *** them,six patients were treated with bortezomib-based *** median overall survival(OS)and progression free survival for the entire cohort were 48 and 33 mo,respectively,which was much worse than the OS reported for MM patients without orbital *** Orbital MM may have significantly shortened survival for the entire cohort,so multidisciplinary collaboration is emphasized and recommended in the diagnosis and treatment of these difficult cases.

关键词： Multiple myeloma Extramedullary disease periorbital Treatment Survival Case report

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Peri-Orbital Non-Invasive and Painless Skin Tightening-Safe and Highly Effective Use of Multisource Radio-Frequency Treatment Platform

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Journal of Cosmetics, Dermatological Sciences and Applications 2015年第3期5卷 206-211页

作者： Isabelle Rousseaux Cabinet de Dermatologie Esthetique Lille Cote Sud Loos France

The periorbital area is the third highest-ranking area for cosmetic surgery. However, surgery in this area presents a number of difficulties and safety concerns. First generation Monopolar RF treatments in this area were usually associated with considerable pain and long downtime. In the present clinical study, we used the iFine handpiece of the EndyMed PRO, multi-source phase-controlled radiofrequency (RF) for Non-invasive, pain free, skin rejuvenation of the periorbital area. The study included eleven (11) subjects, treated for periorbital signs of aging (iFine handpiece, EndyMed PRO platform, EndyMed Medical, Caesarea, Israel). The degree of clinical improvement was assessed by the global aesthetic improvement scale (GAIS) and subjects satisfaction by post treatment questionnaires. 91% of patients showed good to excellent improvement as a result of the treatment. Subjects satisfaction showed that 55% of patients reported that they were very satisfied, 45% were satisfied while none were dissatisfied. There were no incidences of infections, scarring, hypopigmentation, or any other serious complications.

关键词： Facial Tightening Radiofrequency EndyMed 3DEEP^(■) periorbital

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