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Critical values of monitoring indexes for perioperative major adverse cardiac events in elderly patients with biliary diseases

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World Journal of Clinical Cases 2022年第20期10卷 6865-6875页

作者： Zong-Ming Zhang Xi-Yuan Xie Yue Zhao Chong Zhang Zhuo Liu Li-Min Liu Ming-Wen Zhu Bai-Jiang Wan Hai Deng Kun Tian Zhen-Tian Guo Xi-Zhe Zhao Department of General Surgery Beijing Electric Power HospitalState Grid Corporation of ChinaCapital Medical UniversityBeijing 100073China Department of Cardiology Beijing Electric Power HospitalState Grid Corporation of ChinaCapital Medical UniversityBeijing 100073China

BACKGROUND Major adverse cardiac events(MACE) in elderly patients with biliary diseases are the main cause of perioperative accidental death, but no widely recognized quantitative monitoring index of perioperative cardiac function so far.AIM To investigate the critical values of monitoring indexes for perioperative MACE in elderly patients with biliary diseases.METHODS The clinical data of 208 elderly patients with biliary diseases in our hospital from May 2016 to April 2021 were retrospectively analysed. According to whether MACE occurred during the perioperative period, they were divided into the MACE group and the non-MACE group.RESULTS In the MACE compared with the non-MACE group, postoperative complications, mortality, hospital stay, high sensitivity troponin-Ⅰ(Hs-TnI), creatine kinase isoenzyme(CK-MB), myoglobin(MYO), B-type natriuretic peptide(BNP), and Ddimer(D-D) levels were significantly increased(P perioperative MACE, and their cut-off values in the receiver operating characteristic(ROC) curve were 382.65 pg/mL and 0.965 mg/L, respectively.CONCLUSION The postoperative BNP and D-D were independent risk factors for perioperative MACE, with the critical values of 382.65 pg/mL and 0.965 mg/L respectively. Consequently, timely monitoring and effective maintenance of perioperative cardiac function stability are of great clinical significance to further improve the perioperative safety of elderly patients with biliary diseases.

关键词： Biliary diseases in elderly patients Major adverse cardiac events perioperative safety Logistic regression Receiver operating characteristic curve

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