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Risk and management of post-operative infectious complications in inflammatory bowel disease: A systematic review

World Journal of Gastrointestinal Surgery 2023年第11期15卷 2579-2595页

作者： Reshma Kureemun Mowlah Jonathan Soldera Acute Medicine University of South WalesCardiff CF371DLUnited Kingdom

BACKGROUND Indications for surgery in inflammatory bowel disease(IBD)include treatment-refractory disease or severe complications such as obstruction,severe colitis,dysplasia,or *** complications following colorectal surgery in IBD are significant,particularly in high-risk *** To gather evidence on risk factors associated with increased post-operative infectious complications in IBD and explore management strategies to reduce morbidity and *** A systematic review adhering to PRISMA-P guidelines was ***(PubMed)and Cochrane Library databases were searched using specific *** criteria encompassed studies involving patients with IBD under-going abdominal surgery with infectious complications within 30 d *** criteria included patients under 18 years and non-infectious *** papers were analyzed to identify factors contributing to post-operative infections.A narrative analysis was performed to provide eviden-ce-based recommendations for *** data were then extracted and assessed based on the Reference Citation Analysis(https://***/).RESULTS The initial database search yielded 1800 articles,with 330 articles undergoing full-text *** excluding duplicates and irrelevant papers,35 articles were included for *** factors for post-operative complications in patients with IBD included hypoalbuminemia,malnutrition,preoperative abscess,and *** blood transfusion was associated with increased infectious *** such as 5-aminosalicylates and immunomodulators did not increase post-operative *** were associated with an increased risk of *** and vedolizumab showed similar rates of infectious complic-ations compared to other *** impact of minimally invasive surgery on post-operative complications varied across ***

关键词： Inflammatory bowel disease Ulcerative colitis Crohn’s disease peri-operative infections Infliximab

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