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percutaneous resection of upper tract urothelial cell carcinoma:When,how,and is it safe?

Asian Journal of Urology 2016年第3期3卷 134-141页

作者： Willem E.Strijbos Bart van der Heij Department of Urology Zuyderland Medical CentreHeerlenThe Netherlands

Introduction:In the management of upper tract urothelial cell carcinoma(UTUC)endoscopic,nephron sparing procedures like ureterorenoscopy(URS)or percutaneous tumour resection(PCTR)still play a very limited *** could lead to possible unnecessary radical nephroureterectomies(RNU),still being the gold standard *** risk of chronic kidney disease(CKD)later in life is *** this study we present the results of 24-year experience with PCTR in a single ***:We identified 44 patients who underwent PCTR between 1992 and *** resection was achieved in 40 patients who were included in this *** and clinical data,including tumour recurrence,progression to RNU,tumour grade and overall survival(OS)were retrospectively *** outcome analysis was ***:Median age at diagnosis was 68 years(range 42-94 years).Low grade tumours were found in 37 patients(92.5%)and high grade tumours in three patients(7.5%).Median followup was 53 months during which 20 patients developed upper tract recurrences(50.0%).The longest time to recurrence was 97 *** follow-up 11 patients(27.5%)underwent an RNU and two patients died from *** could be avoided in 29 patients(72.5%).In this study we found that multifocality is a significant risk factor for recurrence,but not for stage progression to ***:PCTR is a surgically and oncologically safe *** preservation in patients with UTUC who are eligible for percutaneous resection can be achieved in the majority of *** criteria for PCTR should be further refined,leading to a wider application of PCTR in the ***-up needs invasive procedures and should be long term.

关键词： percutaneous tumour resection PCTR UTUC Endoscopic management Upper tract urothelial cell carcinoma tumour surface area

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