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Efficacy and safety of percutaneous transhepatic biliary radiofrequency ablation in patients with malignant obstructive jaundice

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World Journal of Clinical Cases 2024年第17期12卷 2983-2988页

作者： Ying Xing Zheng-Rong Liu You-Guo Li Hong-Yi Zhang Department of General Surgery Tiantan HospitalBeijing 100170China

BACKGROUND percutaneous transhepatic cholangiodrainage(PTCD)and endoscopic retrograde cholangiopancreatography/endoscopic nasobiliary drainage are the most common clinical procedures for jaundice control in patients with unresectable malignant obstructive jaundice,yet the safety and effect of endobiliary radiofrequency ablation(EB-RFA)combined PTCD is rarely reported,in this article,we report our experience of EB-RFA combined PTCD in such *** To retrospectively study the efficacy and safety of EB-RFA combined PTCD in patients with unresectable malignant obstructive *** Patients with unresectable malignant obstructive jaundice treated with EB-RFA under PTCD were selected,the bile ducts of the right posterior lobe was selected as the target bile ducts in all *** general conditions of all patients,preoperative tumour markers,total bilirubin(TBIL),direct bilirubin(DBIL),albumin(ALB),alkaline phosphatase(ALP),and glutamyl transferase(GGT)before and on the 7th day after the procedure,as well as perioperative complications,stent patency time and patient survival were *** All patients successfully completed the operation,TBIL and DBIL decreased significantly in all patients at the 7th postoperative day(P=0.009 and 0.006,respectively);the values of ALB,ALP and GGT also decreased compared with the preoperative period,but the difference was not statistically *** biliary bleeding occurred in 2 patients,which was improved after transfusion of blood and other conservative treatments,pancreatitis appeared in 1 patient after the operation,no serious complication and death happened after *** for 3 patients with loss of visits,the stent patency rate of the remaining 14 patients was 100%71%and 29%at the 1^(st),3^(rd),and 6^(th)postoperative months respectively,with a median survival of 4 *** EB-RFA under PTCD in patients with unresectable malignant obstructive jaundice has a satisfactory therapeu

关键词： Biliary tract tumour Malignant obstructive jaundice percutaneous transhepatic cholangiodrainage Endoluminal radiofrequency ablation Biliary radiofrequency ablation

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percutaneous transhepatic cholangiography:An effective option for endo-biliary radiofrequency ablation before stent insertion in unresectable biliary cancer?

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World Journal of Clinical Cases 2024年第30期12卷 6413-6416页

作者： Dimitrios S Karagiannakis Academic Department of Gastroenterology Medical School of the National and Kapodistrian University of Athens"Laiko"General HospitalAthens 11527Greece

Biliary cancer is a highly aggressive disease that is typically diagnosed at advanced stages when surgical removal is no longer an *** these cases,palliative care and mechanical widening of the blocked biliary system are *** insertion of a stent is often necessary to prevent the recurrence of blockages caused by cancer *** to stent placement,endo-biliary radiofrequency ablation(EB-RFA)appears to result in longer-lasting stent effectiveness without increasing the risk of severe ***,its impact on overall survival is not yet ***,while endoscopic retrograde cholangiopancreatography is the most common method for performing EB-RFA,percutaneous transhepatic cholangiodrainage seems to be a safe and potentially more efficient alternative,particularly for long,angulated,or significantly narrowed bile ducts.

关键词： Biliary cancer Cholangiocarcinoma Pancreatic cancer percutaneous transhepatic cholangiodrainage Radiofrequency ablation

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Hepatobiliary complications of alveolar echinococcosis: A long-term follow-up study

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World Journal of Gastroenterology 2015年第16期21卷 4925-4932页

作者： Tilmann Graeter Franziska Ehing Suemeyra Oeztuerk Richard Andrew Mason Mark Martin Haenle Wolfgang Kratzer Thomas Seufferlein Beate Gruener Department of Interventional and Diagnostic Radiology University Hospital Ulm Department of Internal Medicine I University Hospital Ulm Louis Stokes Cleveland Department of Veterans Affairs Medical Center Section of Infectious Diseases and Clinical Immunology Comprehensive Infectious Diseases Center Ulm

AIM:To determine the long-term hepatobiliary complications of alveolar echinococcosis(AE) and treatment options using interventional ***:Included in the study were 35 patients with AE enrolled in the Echinococcus Multilocularis Data Bank of the University Hospital of *** underwent endoscopic intervention for treatment of hepatobiliary complications between 1979 and ***' epidemiologic data, clinical symptoms, and indications for the intervention, the type of intervention and any additional procedures, hepatic laboratory parameters(pre- and post-intervention), medication and surgical treatment(pre- and post-intervention), as well as complications associated with the intervention and patients‘ subsequent clinical courses were *** order to compare patients with AE with and without history of intervention, data from an additional 322 patients with AE who had not experienced hepatobiliary complications and had not undergone endoscopic intervention were retrieved and ***:Included in the study were 22 male and 13 female patients whose average age at first diagnosis was 48.1 years and 52.7 years at the time of *** average time elapsed between first diagnosis and onset of hepatobiliary complications was 3.7 *** most common symptoms were jaundice, abdominal pains, and weight *** of interventions per patient ranged from one to *** retrograde cholangiopancreatography(ERCP)was most frequently performed in combination with stent placement(82.9%),followed by percutaneous transhepatic cholangiodrainage(31.4%)and ERCP without stent placement(22.9%).In 14.3%of cases,magnetic resonance cholangiopancreatography was performed.A total of eight patients received a biliary stent.A comparison of biochemical hepatic function parameters at first diagnosis between patients who had or had not undergone intervention revealed that these were significantly elevated in six patients who had undergone interven

关键词： Alveolar echinococcosis Endoscopic retrograde cholangiopancreatography Hepatobiliary complication Magnetic resonance cholangiopancreatography percutaneous transhepatic cholangiodrainage Stent placement Treatment

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