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pedigree analysis of nationally approved soybean cultivars from 1984 to 2013 and implications for breeding

Oil Crop Science 2016年第4期1卷 30-39页

作者： Zhonglu Yang Xiaomin Guan Yanqin He Zhihui Shan Dezhen Qiu Xiaojuan Zhang Limiao Chen Chanjuan Zhang Songli Yuan Shuilian Chen Qingnan Hao Haifeng Chen Xin'an Zhou Key Laboratory of Biology and Genetic Improrement of Oil Crops Ministry of Agriculture Oil Crops Research Institute Chinese Academy of Agricultural Sciences Wuhan China National Extension and Service Center of Agricultural Technology Beijing China

To reveal origins of 316 state authorized varieties from 1984 to 2013, rules of their parentsJ selection including types and hybrid configurations of direct parents, geo-graphical sources and types of their ancestors were analyzed. Various important direct parents and ancestors were summarized and nuclear contribution of ancestors was also estimated by pedigree analysis. Among 316 registered cultivars, 298 （94.3%） were bred by hybridization, and most of their direct parents were cultivars or breeding lines （65.5%）. Cultivars and breeding lines were mostly used as female parents, with 53.0% and 38.7% respectively. The 316 released cultivars were traced to 373 final ancestors, mainly com-posed of landraces （55.5%） and breeding lines （36.7%）. The 373 final ancestors came from different regions, including 121 from northern area, 110 from Huang-Huai-Hai area, 53 from southern area and 76 from abroad. These ancestors were mainly from the same ecologic zone as the approved cultivars. Newly approved cultivars always have more ancestors and a broader genetic base. However, distribution of these ancestors was unbalanced, and a few ancestors provided significant genetic contributions to later generations, such as the most concentrated final ancestors from Huang-Huai-Hai region followed by northern and southern regions. These results offer more information regarding their important parents and provide valuable references to soybean breeding. We should increase soybean germplasm exchanges with different regions and make use of elite lines, foreign cultivars and wild soybean germplasm to broaden the genetic background.

关键词： soybean uniform test nationally approved cultivars pedigree analysis direct parent ancestor genetic base

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Genetic Diversity and Ancestral History of the German Angler and the Red-and-White Dual-Purpose Cattle Breeds Assessed through pedigree analysis

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Agricultural Sciences 2017年第9期8卷 1033-1047页

作者： Sowah Addo Jonas Schaler Dirk Hinrichs Georg Thaller Institute of Animal Breeding and Husbandry Christian-Albrechts-University of KielKielGermany Albrecht Daniel Thaer-Institute of Agricultural and Horticultural Sciences Humboldt UniversityBerlinGermany

Local cattle breeds continue to decline in numbers partly due to the use of high performing breeds in advanced production systems where genetic material of elite animals is widely spread. The objective of this study was to assess the within and across breed genetic diversity of the Angler and Red-and-White dual-purpose (DP) cattle breeds applying different inbreeding concepts. Classical and ancestral inbreeding coefficients were computed from pedigree data using the gene dropping method. Effective population size was calculated based on the increase of classical inbreeding, and based on ancestral inbreeding to obtain what was termed as ancestral effective population size. Furthermore, the effective number of founders and ancestors were computed to assess the disequilibrium of founder contribution in the reference populations. The analyses were performed separately for each breed and for a combined dataset. The Angler pedigree was more complete (88%) in the first parental generation but completeness declined with increasing pedigree depth. Average classical inbreeding coefficients of inbred individuals were 2.19%, 1.94% and 2.07%, while average Ballou’s ancestral inbreeding coefficients were 3.69%, 1.39% and 2.21% for the Angler, Red-and-White DP and the combined breed pedigree analyses, respectively. Ancestral history coefficient is a novel coefficient and its estimates were similar and strongly correlated to Ballou’s coefficients (r = 0.99, p < 0.001). The effective population size estimates ranged from 156 to 170 for the classical inbreeding based method, and as low as from 50 to 54 for the ancestral history coefficient based method. The effective number of founders and ancestors ranged from 310 to 532, and 90 to 189, respectively. Our results show that the Red Holstein breed is a key progenitor of the breed populations under study. This highlights cross breeding schemes introduced to improve the milk trait performance of the Angler and Red-and-White DP breeds som

关键词： Ancestral Inbreeding Effective Population Size pedigree analysis Genetic Diversity Local Cattle

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A pedigree analysis of a Family With Familial Hypercholesterolemia

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South China Journal of Cardiology 2000年第1期1卷 55-57页

作者：李建军王跃玲胡成林陈江斌王晋明许家琍 Department of Cardiology The first Affiliated Hospital Hubei Medical University Wuhan 430060 PR China

Objective The current study was designed to investigate the features of a family with familial hypercholesterolemia(FH). Methods Twenty members of three generations in a family with FH were enrolled in the study. The data collected were from clinical observation and subjected to pedigree analysis. Results The proband was a 41 years old male who suffered from angina pectoris with multi-vessel stenosis of coronary artery at the age of 40. Among 20 members, 8 individuals were demonstrated with hypercholes-terolemia in this family with the total incidence of 40% [54.5% (6/11) in male and 22. 2% (2/9) in femaleThe serum total cholesterol level was elevated in childhood from 7. 1 to 10. 8 mmol/L and tended to be raised with increasing age. In addition, the level of total cholesterol was found to be elevated both in a monozy-gote twin brothers and their offspring in the family. Conclusion FH appears to be a hereditary disease of autosomal dominance inheritance and the outcome of FH patients with coronary heart disease seems to be poor in prognosis.

关键词： Familial hypercholesterolemia Coronary heart disease pedigree analysis

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Genome assembly of KA105,a new resource for maize molecular breeding and genomic research

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The Crop Journal 2023年第6期11卷 1793-1804页

作者： Ting Li Shutu Xu Jiawen Zhao Yapeng Wang Jun Zhang Xin Wei Jianzhou Qu Ruisu Yu Xinghua Zhang Chuang Ma Jiquan Xue The Key Laboratory of Biology and Genetic Improvement of Maize in Arid Area of Northwest Region Northwest A&F UniversityYangling 712100ShaanxiChina Maize Engineering&Technology Research Centre College of AgronomyNorthwest A&F UniversityYangling 712100ShaanxiChina State Key Laboratory of Crop Stress Biology for Arid Areas Center of BioinformaticsCollege of Life SciencesNorthwest A&F UniversityYangling 712100ShaanxiChina

Superior inbred lines are central to maize breeding as sources of natural *** many elite lines have been sequenced,less sequencing attention has been paid to newly developed *** constructed a genome assembly of the elite inbred line KA105,which has recently been developed by an arti-ficial breeding population named Shaan A and has shown desirable characteristics for *** pedigree showed genetic divergence from B73 and other lines in its *** with the B73 reference genome revealed extensive structural variation,58 presence/absence variation(PAV)genes,and 1023 expanded gene families,some of which may be associated with disease resistance.A network-based integrative analysis of stress-induced transcriptomes identified 13 KA105-specific PAV genes,of which eight were induced by at least one kind of stress,participating in gene modules responding to stress such as drought and southern leaf blight *** than 200,000 gene pairs were differentially correlated between KA105 and B73 during kernel *** KA105 reference genome and transcriptome atlas are a resource for further germplasm improvement and surveys of maize genomic variation and gene function.

关键词： Genome assembly pedigree analysis Structural variation Transcriptome atlas Differential network

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Elite sd1 alleles in japonica rice and their breeding applications in northeast China

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The Crop Journal 2022年第1期10卷 224-233页

作者： Hanjing Sha Hualong Liu Guangxin Zhao Zhongmin Han Huilin Chang Jingguo Wang Hongliang Zheng Jifeng Zhang Yang Yu Yuqiang Liu Detang Zou Shoujun Nie Jun Fang Key Laboratory of Soybean Molecular Design Breeding Northeast Institute of Geography and AgroecologyChinese Academy of SciencesHarbin 150081HeilongjiangChina Key Laboratory of Germplasm Enhancement Physiology and Ecology of Food Crops in Cold RegionMinistry of EducationNortheast Agricultural UniversityHarbin 150030HeilongjiangChina Innovation Center Suihua Branch of Heilongjiang Academy of Agricultural SciencesSuihua 152052HeilongjiangChina University of Chinese Academy of Sciences Beijing 100049China College of Life Science and Engineering Shenyang UniversityShenyang 110044LiaoningChina The Innovative Academy for Seed Design Chinese Academy of SciencesBeijing 100101China

The Green Revolution gene sd1 has been used extensively in modern rice breeding,especially in indica ***,elite sd1 alleles and related germplasm resources used for japonica rice breeding have not been identified,and extensive efforts are needed for japonica rice breeding to obtain new dwarfing *** from MBKbase-Rice revealed seven sd1 haplotypes in indica and four in japonica *** new sd1 alleles were identified in indica *** 295 japonica accessions from northeast Asia,except for the weak functional allele SD1-EQ,sd1-r was the major allele,reducing plant height in comparison with *** germplasm resources carrying reported sd1 alleles were identified by genotype searching and further verified by literature search,genealogical analysis,and d Caps *** and geographic distribution showed that sd1-r is an excellent allele widely used in northern China and Tohoku in Japan,and sd1-j is commonly used in east China and Kyushu in ***-and Xiushui-series cultivars carrying sd1-r and sd1-j,respectively,are essential branches of the backbone parents of Chinese japonica rice,Akihikari and Ce21,with the largest number of descendants and derived *** semi-dwarf japonica rice breeding,sd1-d was introgressed into Daohuaxiang 2(DHX2).Dwarf and semi-dwarf lines carrying sd1-d were selected and designated as 1279 and 1280,respectively,after withstanding typhoon-induced strong winds and heavy rains in 2020,and are anticipated to become useful intermediate materials for future genetic research and *** work will facilitate the introduction,parental selection,and marker-assisted breeding,and provide a material basis for the next step in identifying favorable genes that selected together with the sd1 alleles in japonica backbone parents.

关键词： Semi-dwarf breeding Elite allele pedigree analysis Geographic distribution Regional adaptability

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The Clinical Study and HLA Genotyping of 112 Familial Myasthenia Gravis Patients

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Journal of Huazhong University of Science and Technology(Medical Sciences) 1999年第1期19卷 47-50页

作者：卜碧涛杨明山徐金枝龚非力姜晓丹聂小波

Summary: One hundred and twelve cases of familial myasthenia gravis (MG) from 44 families selected from 2100 patients with MG diagnosed since 1983 in the Department of Neurology were studied. The clinical pictures and immunological features of the patients showed a great resemblance to those of sporadic cases. The pedigree analysis disclosed that the hereditary patterns of familial patients were basically Mendellian autosomal inheritance. Many predisposing factors such as fever, infection, use of aminoglycoside or vaccines, played an important role in presenting the phenotype of subclinical cases. The HLA genotyping suggested that the complement polymorphism C4A*4, the complotype S42, and the genes 0901 and 1301 of DRB1 allele, were related to the pathogenesis of MG. It was concluded that the phenotype of MG may be the result of interaction between hereditary defects and environmental factors.

关键词： familial myasthenia gravis Mendellian autosomal inheritance HLA genotyping pedigree analysis

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