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Should few retrieved oocytes be as an indication for intracytoplasmic sperm injection?

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012年第9期13卷 717-722页

作者： Qing-song XI Li-xia ZHU Juan HU Li WU Han-wang ZHANG Reproductive Medicine Center Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China

Objective:To reevaluate whether relatively few oocytes obtained in one cycle are an indication for intracytoplasmic sperm injection(ICSI).Methods:A total of 406 cycles with three or fewer retrieved oocytes performed in 396 non-male infertile couples were retrospectively *** were classified into three groups by different fertilization techniques:the in vitro fertilization(IVF) group,insemination with conventional IVF;the ICSI group,insemination with ICSI though semen parameters were normal;and the rescue ICSI group,re-insemination with ICSI after conventional IVF ***:The ICSI group resulted in higher normal fertilization compared with the conventional IVF ***,the cycle cancellation rate was decreased in the ICSI group,though it was not statistically *** clinical pregnancy rate and implantation rate were lower in the ICSI group compared with the conventional IVF *** ICSI was a method to avert total fertilization failure in conventional IVF,increasing fertilization and ensuring embryo availability for transfer,but the normal fertilization was the lowest due to delayed insemination and the chance of pregnancy was very ***:Obtaining only few oocytes in one cycle is not considered as an indication for ICSI when the sperm sample is apparently *** ICSI is either not recommended if conventional insemination *** patients should not be subjected to the unnecessary costs and potential risks of ICSI.

关键词： Fertilization rate Intracytoplasmic sperm injection (ICSI) Indication Oocyte number patient age

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