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pancreatic paraganglioma diagnosed by endoscopic ultrasoundguided fine needle aspiration: A case report and review of literature

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World Journal of Gastroenterology 2021年第37期27卷 6322-6331页

作者： Gandhi Lanke John M Stewart Jeffrey H Lee Department of Gastroenterology Hepatology and NutritionMD Anderson Cancer CenterLubbockTX 79407United States Pathology-lab Medicine Division MD Anderson Cancer CenterHoustonTX 77030United States Department of Gastroenterology Hepatology and NutritionMD Anderson Cancer CenterHoustonTX 77030United States

BACKGROUND pancreatic paragangliomas(PPGL)are rare benign neuroendocrine neoplasms but malignancy can *** are often misdiagnosed as pancreatic neuroendocrine tumor or pancreatic *** SUMMARY We reviewed 47 case reports of PPGL published in PubMed to *** patients(15/47)with PPGL underwent endoscopic ultrasound-guided fine needle aspiration(EUS-FNA).Only six(6/15)were correctly diagnosed as *** patients with PPGL underwent surgical resection except three(one patient surgery was aborted because of hypertensive crisis,two patients had metastasis or involvement of major vessels).Our patient remained on close surveillance as she was *** Accurate preoperative diagnosis of PPGL can be safely achieved by EUS-FNA with *** team approach should be considered to bring the optimal results in the management of PPGL.

关键词： pancreatic paraganglioma Endoscopic ultrasound-guided fine needle aspiration Meta-iodobenzylguanidine scan Metanephrines GATA-3 Immunohistochemistry Case report

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Castleman disease of the pancreas mimicking pancreatic malignancy on^(68)Ga-DOTATATE and 18F-fluorodeoxyglucose positron emission tomography/computed tomography:A case report

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World Journal of Gastrointestinal Surgery 2022年第5期14卷 514-520页

作者： Sheng-Lu Liu Ming Luo Hao-Xian Gou Xiao-Li Yang Kai He Department of General Surgery(Hepatobiliary Surgery) The Affiliated Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province The Affiliated Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Academician(Expert)Workstation of Sichuan Province The Affiliated Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina

BACKGROUND Castleman disease is an uncommon nonclonal lymphoproliferative disorder,which frequently mimics both benign and malignant abnormalities in several *** on the number of lymph nodes or regions involved,Castleman disease(CD)varies in diagnosis,treatment and *** rarely occurs in the pancreas alone without any distinct clinical feature and tends to be confused with pancreatic paraganglioma(PGL),neuroendocrine tumors(NETs),and primary tumors,thus impeding proper diagnosis and *** SUMMARY A 28-year-old woman presented with a lesion on the neck of the pancreas,detected by ultrasound during a health *** examination and laboratory findings were *** mass showed hypervascularity on enhanced computed tomography(CT),significantly increased 18F-fluorodeoxyglucose uptake on positron emission tomography(PET)/CT,and slightly increased somatostatin receptor(SSTR)expression on^(68)Ga-DOTATATE PET/CT,suggesting no distant metastases and subdiagnoses such as pancreatic PGL,NET,or primary *** pathology suggested lymphatic hyperplasia,and only simple tumor resection was *** patient was diagnosed with the hyaline vascular variant of CD,which was confirmed by postoperative *** patient was discharged successfully,and no recurrence was observed on regular *** High glucose uptake and slightly elevated SSTR expression are potentially new diagnostic features of CD of the pancreas.

关键词： Castleman disease pancreatic malignancy pancreatic neuroendocrine tumors pancreatic paraganglioma Positron emission tomography Case report

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