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Desmoid type fibromatosis: A case report with an unusual etiology

World Journal of Gastrointestinal Oncology 2017年第9期9卷 385-389页

作者： Syed Faisal Jafri Obada Obaisi Gerardo G Vergara Joe Cates Jaswinder Singh Jennifer Feeback Harathi Yandrapu Gastroenterology Research Medical CenterKansas City School of Medicine University of Missouri in Kansas City Pathology Research Medical CenterKansas City General and Vascular Surgery Research Medical CenterKansas City Hematology/Oncology Research Medical CenterKansas City Clinical Research Research Medical CenterKansas City Internal Medicine Department of Research Medical Center and Research Department of Kansas City Veterans Affairs Medical Center

Desmoid type fibromatosis(DTF) is a rare, locally invasive, non-metastasizing soft tissue tumor. We report an interesting case of DTF involving the pancreatic head of a 54-year-old woman. She presented with intermittent dysphagia and significant weight loss within a 3-mo period. Laboratory findings showed mild elevation of transaminases, significant elevation of alkaline phosphatase and direct hyperbilirubinemia, indicating obstructive jaundice. Computerized tomography of the abdomen revealed a mass in the head of the pancreas, dilated common bile duct, and dilated pancreatic duct. Endoscopic retrograde cholangiopancreatography and endoscopic ultrasound showed a large hypoechoic massin the head of the pancreas causing extrahepatic biliary obstruction and pancreatic ductal dilation. The patient underwent a successful partial pancreatico-duodenectomy and cholecystectomy. She received no additional therapy after surgery, and liver function tests were normalized within nine days after surgery. Currently, surgical resection is the recommended first line treatment. The patient will be followed for any recurrence.

关键词： Desmoid type fibromatosis Desmoid tumor Aggressive fibromatosis Pancreas painless jaundice

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